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Knight, who acknowledges at the outset that the term "mental retardation" is offensive (it was used for the title because it remains the commonest term worldwide), has gathered 12 articles on recent research, along with an introductory chapter giving the personal story of a mother and the long wait for a genetic diagnosis of her child's unusual autism. Researchers in Europe and the US report on their work, with discussion of genome architecture, clinical evaluation, database aids, 3D shape and molecular analyses of facial dysmorphology, monogenic causes, and the microdeletion/duplication syndromes, among other topics. This is a well-balanced, authoritative work that will be essential both to practitioners working with issues of treatment and diagnosis and researchers. Annotation c2010 Book News, Inc., Portland, OR (booknews.com)
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