In the first hundred years of its history, the problems of species and specificity were the core problems of research and practice in immunology. The old botanical dispute about the nature of species reappeared in the late nineteenth century in the disputes of the bacteriologists, to be followed by their students, the immunologists, immunochemists and blood group geneticists. In the course of this controversy, Mazumdar argues, five generations of scientific protagonists make themselves aggressively plain. Their science is designed only in part to wrest an answer from nature: it is at least as important to wring an admission of defeat from their opponents. One of those on the losing side of the debate was the German immunochemist Karl Landsteiner, whose unitarian views were excluded from the state health and medical institutions of Europe, where specificity and pluralism, the legacies of Robert Koch and Paul Erlich, were entrenched.
Myths! Lies! Secrets! Uncover the hidden truth about history’s pandemics, from the Black Death to COVID-19. Perfect for fans of I Survived! and Nathan Hale’s Hazardous Tales.During the Black Death in the 14th century, plague doctors wore creepy beaked masks filled with herbs. RIGHT?WRONG! Those masks were from a plague outbreak centuries later―and most doctors never wore anything like that at all!With a mix of sidebars, illustrations, photos, and graphic panels, acclaimed author Kate Messner delivers the whole truth about diseases like the bubonic plague, cholera, smallpox, tuberculosis, polio, influenza, and COVID-19.Discover the nonfiction series that smashes everything you thought you knew about history! Don’t miss History Smashers: The Mayflower, Women’s Right to Vote, Pearl Harbor, Titanic, and American Revolution.
'Big data' poses challenges that require both classical multivariate methods and contemporary techniques from machine learning and engineering. This modern text equips you for the new world - integrating the old and the new, fusing theory and practice and bridging the gap to statistical learning. The theoretical framework includes formal statements that set out clearly the guaranteed 'safe operating zone' for the methods and allow you to assess whether data is in the zone, or near enough. Extensive examples showcase the strengths and limitations of different methods with small classical data, data from medicine, biology, marketing and finance, high-dimensional data from bioinformatics, functional data from proteomics, and simulated data. High-dimension low-sample-size data gets special attention. Several data sets are revisited repeatedly to allow comparison of methods. Generous use of colour, algorithms, Matlab code, and problem sets complete the package. Suitable for master's/graduat
Myths! Lies! Secrets! Uncover the hidden truth about Christopher Columbus, and learn all about the Taino people. Perfect for fans of the I Survived books and Nathan Hale's Hazardous Tales.In 1492, Christopher Columbus sailed across the ocean and discovered America. Right? WRONG! Columbus never actually set foot in what is now the United States. His voyages took him to islands in the Caribbean and along the coast of South America. The truth is, when Columbus first arrived, Indigenous peoples, including the Taino, had been living there for thousands of years, raising their families, running their societies, and trading with their neighbors. He didn’t “discover” the lands at all! And his name? Not even really Christopher Columbus! Cowritten by bestselling author Kate Messner and our country’s premier Taino scholar, this fascinating addition to the series is the one that teachers have been asking for and that kids need to read.Discover the nonfiction series that demolishes everything you t
