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分子生物學(附光碟)(簡體書)
  • 分子生物學(附光碟)(簡體書)

  • ISBN13:9787040256550
  • 出版社:高等教育出版社
  • 作者:(美)特羅普
  • 裝訂/頁數:平裝/1000頁
  • 附件:附光碟
  • 規格:26cm*19cm (高/寬)
  • 版次:一版
  • 出版日:2008/12/01
人民幣定價:96元
定  價:NT$576元
可得紅利積點:17 點

無庫存,下單後進貨(採購期約45個工作天)

商品簡介

目次

書摘/試閱

《分子生物學:從基因到蛋白質(第3版)(影印版)》前兩版書名是《分子生物學》,分別在1983年和1987年出版,由先後在Brandeis大學和加州大學聖地亞哥分校教授生物化學和分子生物學課程的DavidFreifelder教授編寫并修訂的。
Preface

CHAPTER 1 Introduction to Molecular Biology

SECTION 1 Protein Structure and Function

CHAPTER 2 Protein Structure

CHAPTER 3 Protein Function



SECTION 2 Nucleic Acids and Nucleoproteins

CHAPTER 4 Deoxyribonucleic Acid Structure

CHAPTER 5 Nucleic Acid Technology

CHAPTER 6 Chromosome Structure



SECTION 3 Genetics and Virology

CHAPTER 7 Genetic Analysis in Molecular Biology

CHAPTER 8 Viruses in Molecular Biology



SECTION 4 DNA Metabolism

CHAPTER 9 DNA Replication

CHAPTER 10 DNA Damage and Repair

CHAPTER 11 Recombination

CHAPTER 12 Transposons and Other Mobile Elements



SECTION 5 RNA Synthesis and Processing

CHAPTER 13 Bacterial RNA Polymerase

CHAPTER 14 Regulation of Bacterial Gene Transcription

CHAPTER 15 RNA Polymerase Ⅱ: Basal Transcription

CHAPTER 16 RNA Polymerase Ⅱ: Regulation

CHAPTER 17 RNA Polymerase Ⅱ: Cotranscriptional and Posttranscriptional Processes

CHAPTER 18 Ribosomal RNA, Transfer RNA, and Organellar RNA Synthesis



SECTION 6 Protein Synthesis

CHAPTER 19 Protein Synthesis: The Genetic Code

CHAPTER 20 Protein Synthesis: The Ribosome

Index
These nucleases, which were called restriction endonudeasesbecause they blocked or restricted viral replication, act only on DNAwith specific recognition sequences and only when the recognition sequences are not modified. Host DNA is protected because it has methylgroups attached to specific bases within the recognition sequence.

  Three major types of restrictionmodification systems have beenstudied (Table S.2). Type I restrictionmodification systems consist offive polypeptide subunits: two identical restriction endonuclease subunits (R), two identical modification subunits (M), and a specificitysubunit (S). If the sequence that is recognized by the specificity subunitdoes not have a methyl group, then one of two things will happen. Themodification subunits will methylate the sequence and the DNA willbe protected, or the restriction subunits will cleave the DNA at a nonspecific site, often I kb or more from the recognition sequence, and theDNA will be degraded. Type II restrictionmodification systems aremade of two independent enzymes, a homodimeric restriction endonuclease and a monomeric methyl transferase (methylase). Type 1I restrictionmodification enzymes recognize sequences that are 4 to 8 bp long.Type II methylases transfer methyl groups to bases within the recognition sequence and type II endonucleases cleave DNA within the recognition sequence. Type III restrictionmodification systems consist oftwo subunits, a modification subunit and a restriction subunit. Modification occurs within the recognition sequence but cleavage takesplace about 25 bp away from this site. The discussion that follows islimited to the type II endonucleases because they are the only one of thethree types that has been widely used to manipulate DNA.

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