Cell Biology(細胞生物學)(第二版)（簡體書）

《雙語教材：CellBiology細胞生物學（第2版）》由復旦大學生命科學院細胞教學組牽頭，組織國內外綜合、師範、醫學、農林等有關院校的11位多年從事細胞和分子生物學教學及科研的教授和專家，並在美國科學院院士、著名分子細胞生物學家GeorgeeR.stark教授直接指導下編寫完成。在系統闡述細胞各部分的結構和功能的基礎上，重點介紹了物質運輸、信息傳遞、能量轉換、週期調控、分化發育、癌變、免疫、衰老與凋亡等細胞的重大生命活動。正文全部用英語編寫，語言上做到簡練與通俗，科學上做到精確與先進；既介紹細胞生物學的基本概念和基本原理，又反映各領域的發展前沿。為便於讀者自學並同時掌握中、英文雙語概念，各章尾附有思考題，教材的附錄為細胞生物學常用詞匯的中文解釋。

《雙語教材:細胞生物學(第2版)》可供綜合性大學、師范院校、醫學院校、農林院校的本科生和研究生使用，也可供教師、科研人員與科教管理人員參考。

Chapter 1 Introduction to cell biology
1.1 What is cell biology
1.2 The cell theory
1.3 Cell is the basic unit of life
1.4 Diversity of cells
1.5 The prokaryotic cell
1.6 The eukaryotic cell
1.7 Morden cell biology
1.8 The technology of cell biology
1.9 Training the scientists of tomorrow

Chapter 2 Chemical components of cells
2.1 Chemical bonds
2.2 Organic molecules

Chapter 3 Biomembrane and cell surface
3.1 Components and structure of biomembranes
3.2 Plasma membrane
3.3 Transmembrane transport
3.4 Cell junction and adhesion molecules
3.5 Extracellular matrix and cell wall

Chapter 4 Intracellular compartments and transport
4.1 Organelles
4.2 Protein sorting inside cell
4.3 Molecular mechanisms of vesicular transport
4.4 Secretory pathways
4.5 Endocytic pathways

Chapter 5 Mitochondria and chloroplasts
5.1 Mitochondria and oxidative phosphorylation
5.2 Chloroplasts and photosynthesis
5.3 The origins of chloroplasts and mitochondria Chapter
6 Cytoskeleton
6.1 Microtubules
6.2 Actin filaments
6.3 Intermediate filaments

Chapter 7 Cell communication and signaling
7. ] Signaling molecules and their receptors
7.2 Nitric oxide crosses the plasma membrane and actives intracellular enzymes directly
7.3 Functions of cell surface receptors
7.4 Signal network system
7.5 Cell signaling and the cytoskeleton
7.6 Cell communication in plants

Chapter 8 Nucleus and chromosomes
8.1 The nucleus of a eukaryotic cell
8.2 The nuclear envelope
8.3 Structure of the nuclear pore complex and its role in nucleocytoplasmic exchange
8.4 Chromosomes and chromatin
8.5 Nucleolus and ribosome biogenesis
8.6 The nuclear matrix

Chapter 9 Cell cycle and cell division
9.1 An overview of the cell cycle
9.2 Regulation of the cell cycle
9.3 Cell division

Chapter 10 Cell differentiation
10.1 Introduction
10.2 Cells with potency of differentiation
10.3 Stem cells
10.4 Epigenetic view of cell differentiation
10.5 The major cell differentiation systems

Chapter 11 Cell senescence and apoptosis
11.1 Senescence
11.2 Apoptosis
11.3 Senescence versus apoptosis
Chapter 12 Cells in immune system
12.1 The immune system
12.2 The organs of the immune system
12.3 Innate and adaptive immune systems
12.4 Innate immune system
12.5 Adaptive immune system

Chapter 13 Cancer cells
13.1 Basic knowledge about cancer cell
13.2 Carcinogenesis
13.3 The genes involved in cancer
13.4 The genetic and epigenetic changes of cancer
13.5 Diagnosis and treatment of cancer
References
Glossary

Although biochemistry and molecular biology, as disciplines, might have made substantial development without the advent of the cell theory, each science has strongly influenced the other almost from the start.Contemporary cell biology, often referred to as Molecular Cell Biology, or Cell and Molecular Biology, is then a compilation of four separation disciplines:①Cell physiology, which takes a comparative approach looking at how cells answer universal problems, from water conservation to cell communication；②Systemic physiology, which is the science of organ systems and whole organism physiology, such as insect, plant, fish or human physiology； ～Biochemistry, which looks at the chemical and physical commonality of the mechanisms of cellular reactions； @Molecular biology, which studies the properties of organisms through the constituent molecules.
（1）Genetic control in celle The molecular basis of genetic control in cells, particularly in eukaryotic cells is one of the most basic active areas of molecular cell biology.Of particular interest is the understanding of the regulation mechanisms involved in the development of multicellular organisms.In most well-known case studies, such as in the fruit fly Drosophila melanogaster, it has been shown that regulation among the genes thatcontrol early development and cell differentiation.
Genes are the blueprint of our bodies, a blueprint that creates the variety of proteins essential to any organism's survival.These proteins, which are used in countless ways by our bodies, are produced by genetic sequences, i.e.our genes, as described in the cell biology section, protein synthesis pages.Some other genes that will be functional during specialization determine the physical characteristics of the cell, i.e.long and smooth for a muscle cell or indented like a goblet cell.
（2）Three flows within celle Cells can be described by the processes that take place within them.The functions of the cell can be broken down into three basic flows: ①flow of information；②flow of mass；③ flow of energy.
None of these three flows operates in isolation from the other two.The flow of mass and flow of energy are extremely closely linked, as biological molecules are broken apart to make other biological molecules or to harvest energy.
1）Flow of information: The flow of information in the cell is described simplistically by the Central Dogma of Molecular Biology-"DNA makes DNA makes RNA makes
protein" （ Figure 1-8） .