Protein Homeostasis
- 系列名:Perspectives Cshl
- ISBN13:9781621822967
- 出版社:Cold Spring Harbor Laboratory Pr
- 作者:Jeffery W. Kelly (EDT); Franz-ulrich Hartl (EDT); Richard Morimoto
- 裝訂/頁數:精裝/350頁
- 規格:26cm*18.4cm*3.2cm (高/寬/厚)
- 版次:2
- 出版日:2019/04/30
定 價:NT$ 7155 元
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Correct folding of proteins is critical for cell function, and accumulation of misfolded proteins is a feature of a number of neurodegenerative conditions. This book examines the mechanisms that ensure proper protein folding of proteins and dispose of misfolded proteins and how this may go awry in disease.
Topics covered in this essential volume include:
- Structural Insights in Amyloids and Prion Diseases
- Early Events in the Endoplasmic Reticulum Unfolded Protein Response
- Mitochondrial Proteolysis and Metabolic Control
- Structure, Function, and Regulation of the Hsp90 Machinery
- Cell Non-Autonomous Regulation of Proteostasis in Aging and Disease
- Proteome-scale Mapping of Perturbed Proteostasis in Living Cells
Topics covered in this essential volume include:
- Structural Insights in Amyloids and Prion Diseases
- Early Events in the Endoplasmic Reticulum Unfolded Protein Response
- Mitochondrial Proteolysis and Metabolic Control
- Structure, Function, and Regulation of the Hsp90 Machinery
- Cell Non-Autonomous Regulation of Proteostasis in Aging and Disease
- Proteome-scale Mapping of Perturbed Proteostasis in Living Cells
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