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It has been well known that chronic airway inflammation may cause respiratory tract obstruction. It leads to wheezing, short-ness of breath, chest tightness, coughing and other respiratory presentations. The manifestations of the disease, degrees of air-way obstruction, and clinical symptoms differ among individuals.
The severity of asthma in an individual also varies over time.Severe asthma is defined as asthma that requires stage 4 or 5 treatments to prevent it from becoming"uncontrolled" or that which remains"uncontrolled"despite such treatments. Therefore,the differentiation between uncontrolled and severe asthma is relatively important.
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