商品簡介
This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
作者簡介
Oljan Repic is the author of Principles of Process Research and Chemical Development in the Pharmaceutical Industry, published by Wiley.
目次
The Ideal.
Impure Thoughts.
Going All the Way.
Resolutions.
Mirrors.
Au Naturel.
Radiant.
License.
The Future.
Index.
