商品簡介
The handbook is intended to provide a comprehensive overview of recent developments in knowledge about the receptors' structure and function, activity and its regulators, dimerization and oligomerization, and role in drug discovery. Researchers mostly in pharmacology but also other fields consider such topics as regulated membrane trafficking and proteolysis, heterotrimeric G proteins and their effector pathways, G protein-coupled receptor kinases, biophysical and biochemical methods to study receptor oligomerization, the modulation of receptor pharmacology by G protein-coupled receptor dimerization, the conformational plasticity of binding sites, de- orphanizing the receptors and drug development. Annotation c2005 Book News, Inc., Portland, OR (booknews.com)
