Indigenous peoples can be found in practically every region of the world, living on ancestral homelands in major cities, rainforests, mountain regions, desert plains, the arctic, and small Pacific Islands. Their languages, knowledges, and values are rooted in the landscapes and natural resources within their territories. However, many Indigenous peoples are now minorities within their homelands and globally, and there is a dearth of research based on Indigenous epistemologies and methodologies. Furthermore, academic research on Indigenous peoples is typically based on western lenses. Thus, the paucity of Indigenous methodologies within mainstream research discourses present challenges for implementing practical research designs and interpretations that can address epistemological distinctiveness within Indigenous communities. There is therefore the need to articulate, as well as bring to the nexus of research aimed at fostering sustainable development, a decolonising perspective in research design and practice. This is what this book wants to achieve. The contributions critically reflect on Indigenous approaches to research design and implementation, towards achieving the sustainable development goals, as well as the associated challenges and opportunities. The contributions also advanced knowledge, theory, and practice of Indigenous methodologies for sustainable development.