The adaptive immune system ensures that our bodies remember pathogens so that we can rapidly mount an immune response if they are encountered again, without succumbing to infection. This volume examin
Correct folding of proteins is critical for cell function, and accumulation of misfolded proteins is a feature of a number of neurodegenerative conditions. This book examines the mechanisms that ensur
Electronic devices can now be used to analyse and modulate the electrical activity within the nervous system. This book explores how development of these devices is leading to new diagnostics and trea
An Introduction to Nervous Systems presents the principles of neurobiology from an evolutionary perspective—from single–celled organisms to complex invertebrates such as flies—and is ideal for use as
Immune tolerance ensures that the immune system generates T-cell and B-cell populations that react to foreign antigens rather than endogenous molecules.
The Laboratory that bears the Cold Spring Harbor name is famous for its research, its role in science education, and the science that won three recent Nobel prizes. This book, an intellectual history
In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daun
Cytokines are small proteins released by cells that regulate the behavior of other cells. They include interferons, interleukins, and tumor necrosis factor and are important regulators of the immune
The 81st Cold Spring Harbor Symposium focused on Targeting Cancer. The implications of how the underlyingscience can drive improvements in diagnostic, prognostic, and therapeutic approaches was a majo
The 81st Cold Spring Harbor Symposium focused on Targeting Cancer. The implications of how the underlyingscience can drive improvements in diagnostic, prognostic, and therapeutic approaches was a majo
The way we treat cancer is about to change forever. This revolutionand it is precisely thatwas sparked not by the invention of a new drug, but by the evolution of an entirely new way of thinking about
Ion channels convey ions such as potassium, sodium and calcium across cellular membranes and play critical roles in normal physiology. This laboratory manual is based on the popular Cold Spring Harbor
The ability to grow new tissue and organs is an important goal of regenerative medicine. This book discusses new research in which cells are grown on artificial scaffolds to build replacement tissue t
Most animal cells are polarized, with structurally and functionally distinct regions. This polarization facilitates processes such as differentiation and morphogenesis, directional cell migration, ner
Hundreds of genomes have been completely sequenced in the past decade, significantly advancing our understanding of genome structure and function. Genomes comprises a collection of review articles rep
Barbara McClintock was born in 1902, within a few years of the rediscovery of Mendel's laws. Her life, discoveries, and insights span the history of genetics in this century. In the 1920s, she became
The 82nd Cold Spring Harbor Symposium focused on Chromosome Segregation & Structure and addressed theenormous progress in our understanding of the nature and behavior of chromosomes during the life cy
Viruses that are transmitted via the fecal-oral route and may cause liver damage are known as enteric hepatitis viruses. These viruses, which include the hepatitis A and E viruses (HAV and HEV, respec
