Instead of providing black box-like general commercial software packages, this tutorial-style book develops the R functions and algorithms necessary to customize adaptive designs to meet their needs.
Reflecting the state of the art in adaptive design approaches, Adaptive Design Theory and Implementation Using SAS and R provides a concise, unified presentation of adaptive design theories, uses SAS
This book focuses on the fundamental principles behind scientific methods. The author uses concrete examples and illustrations to introduce and explain principles. He also uses analogies to connect di
Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics,
Chang, the vice president of biometrics at AMAG Pharmaceuticals, offers a comprehensive textbook that may also serve as a reference of paradoxes encountered in scientific and mathematical reasoning. H
Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics,
"Preface Drug development, aiming at improving people's health, becomes more costly every year. The pharmaceutical industry must join its efforts with government and health professions to seek new, in
Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA’s recent draft guidance, a new edition of one of the first books on the topic is need
Personalized medicine has the potential to change the way we think about, identify, and manage health problems. In the pharmaceutical industry, it is already having an exciting impact on both clinical
