Siddhartha Mukherjee

WINNER OF THE GUARDIAN FIRST BOOK AWARD 2011 WINNER OF THE PULITZER PRIZE FOR NON-FICTION 2011 ‘Profound, eloquent and searching’ SUNDAY TIMES ‘Essential reading’ INDEPENDENT ‘Masterly’ GUARDIAN ‘Extraordinary’ NEW YORK TIMES BOOK REVIEW Riveting, audacious and now more urgent than ever in this vast update, The Emperor of All Maladies is a masterpiece. The story of cancer is a human one – a tale of chance discoveries, seized opportunities and human endurance. From innovative early surgeries to the Curies’ ultimately tragic work with radiation; from Sidney Farber’s hugely risky discovery of chemotherapy to the author’s treatment of his own patients, The Emperor of All Maladies is a profound and revelatory portrait of an enigmatic disease humans have lived with, and perished from, for more than five thousand years.In this updated edition of Siddhartha Mukherjee’s instant classic, four new chapters reveal what has changed in the universe of cancer in the years since the book was first pub

Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize!Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more!In The Song of the Cell, the extraordinary author of the Pulitzer Prize-winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” (Oprah Daily).Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex l

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiolo

The #1 New York Times bestseller from the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously,

★ 普立茲獎得主震撼巨作，重新定義「人類是誰」★ 從DNA到基因編輯，揭開生命最深層的祕密★ 科學 × 家族故事 × 人性倫理，最動人的科普經典基因，是人類歷史上最強大、也最危險的概念之一。從孟德爾的豌豆實驗，到DNA的發現，再到改寫生命的CRISPR基因編輯技術，這不只是一段科學進展史，更是一場關於「我們是誰」的深刻追問。悉達多．穆克吉以醫師與研究者的視角，串聯百年來的科學突破，同時融入自身家族面對精神疾病的故事，讓冰冷的基因研究，轉化為關於命運、遺傳與選擇的動人敘事。當我們逐漸掌握改寫生命的能力，也同時站在倫理與未來的十字路口——我們該如何使用這份力量？這是一部兼具科學深度與文學美感的經典之作，帶領讀者理解基因如何塑造人類，也讓我們思考，未來將由誰來定義人類。Selected as a Book of the Year by The New York Times, The Economist, Independent, Observer and Mail on SundayTHE NEW YORK TIMES NUMBER ONE BESTSELLER SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 ‘Dramatic and precise… [A] thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time… He is a natural storyteller… A page-turner… Read this book and steel yourself for what comes next’Bryan Appleyard, Sunday TimesThe Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.Spanning

The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is

From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies—a magnificent history of the gene and a response to the defining question of the future: What becomes of being human

Essential, required listening for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known princi

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principl

The Laws of Medicine follows Pulitzer-Prize-winning author, Dr Mukherjee as he investigates some of the most perplexing and illuminating cases of his career - the cases that ultimately led him to iden

Now in paperback, the New York Times bestselling, universally acclaimed, “majesterial,”* beautifully written “biography” of cancer—“a compulsively readable, surprisingly uplifting, and vivid tale…that

The Emperor of All Maladies is a magnificently written "biography" ofcancer--from its origins to the epic battle to cure, control, and conquer it.

A 2017 National Book Critics Circle Award finalist In our unique genomes, every one of us carries the story of our species—births, deaths, disease, war, famine, migration, and a lot of sex. But those

獲普立茲非文學獎、《衛報》新人奬、《紐約時報》年度好書 《衛報》評審盛讚：（本書）應該提名「僅此一部作品獎」！ 穆克吉：「寫《萬病之王》耗盡了我所有故事，沒收了我通往寫作國度的護照，扣押了我未來做為作者的權利，我再沒有事物要說了。」 ★ 2010年《紐約時報》年度好書 ★ 2011年普立茲獎非文學類 ★ 2011年英國《衛報》新人獎 ★《時代雜誌》評選為最具影響力的100本書 ★ 美國亞馬遜讀者4.7顆星推薦 這是一本癌症的傳記，也是人類與癌症搏鬥的生命故事…… 本書是精彩而深刻人性化的癌症「傳記」，從數千年前首篇記載的文獻，到二十世紀的治療與控制；從征服它如史詩般壯烈的戰役，到對它本質的全新理解。穆克吉身兼醫師、研究員和奪得大獎的科學作家，以分子生物學者的精準，歷史學家的視野和傳記作家的熱情來檢視癌症，創作出這本既流暢又深入淺出的癌症疾病史。 癌症治療是集合人類聰明才智、彈性與毅力的傳奇，但也是交織了人類傲慢、顢頇和誤解的故事。穆克吉細數幾世紀以來的發現、挫折、勝利和死亡；透過前輩和同僚的眼光，細述人類如何集眾人之智慧，對抗一個三十年前人們以為可以輕易征服的勁敵，但如今世人才發現，這個敵人不僅資源無限，實力也很強大。 本書不僅讓讀者一窺未來癌症治療的堂奧，指引出癌症醫學發展的新方向外，對於不斷找尋解開癌症之謎的人，亦給予了輪廓清晰的解答。癌症被喻為是本世紀最可怖的敵人，透過深入探究其歷史，知識之力量將轉化為人類未來無限的希望。

破解基因，是人類最偉大的冒險，還是最危險的浩劫？ 當人類取代上帝，打造完美基因、根除致命因子， 《X戰警》、《惡靈古堡》的時代已經來臨！ 電影《羅根》取材自他的研究， 「金鋼狼」休‧傑克曼盛讚：「本書超吸引人！」 人類從何而來？該往何處而去？ 普立茲獎得主、紐約時報暢銷書《萬病之王》作者辛達塔．穆克吉 以一本書貫穿基因千年來對人類的影響 ★ 比爾．蓋茲2016年最愛書籍 ★《紐約時報》（New York Times）暢銷書榜首 ★《紐約時報》（New York Times）年度十大好書 ★《華盛頓郵報》（Washington Post）年度必讀書籍 ★《西雅圖時報》（Seattle Times）年度最佳書籍 ★ Amazon年度TOP 20 ★ Amazon超過八百位讀者滿分五顆星推薦 普立茲獎得主、英國衛報新人獎得主、暢銷書《萬病之王》作者最新力作 一八五六年，在滿是荊棘、搖搖欲墜的聖奧斯定修道院裡，開啟了一切探索人類從何而來、走向何方的旅程。當達爾文、拉馬克等生物學家還在為突變是天擇論還是父母遺留變異而爭論時，年輕的見習神父孟德爾擊破停滯了兩千年的遺傳理論，發現親子間的相同與相異都自有一套規則可循，繼而激勵後人積極尋找遺傳的關鍵鑰匙。 受到孟德爾的研究啟發，科學家發現這個讓代代之間彼此「相像」的祕密，實際存在於每個細胞的染色體上。這項遺傳研究成果與達爾文的演化論結合，被運用於優生學上，二戰時造成無數猶太人與雙胞胎遭受人體實驗、監禁及謀殺。一九五三年，基因研究走入新的境界，科學家破解DNA化學結構，發現我們的技術足以提取各類癌症、罕見疾病等致病基因，甚至能在胚胎期「定製」完美生命，這些重大發現彷彿昭示著變種人、複製人以及實驗室生化危機將不再是虛幻故事，人類對完美的追求、對道德倫理的堅持，究竟孰輕孰重？異於常人的生命，該被滅絕嗎？ 作者穆克吉醫師以一場感傷的家族探病之旅為始，細細描述破譯遺傳基因之謎的百年過程，數以千計的科學家如何透過不斷實驗及互相合作、彼此競爭，解開一道道謎題，又衍生一項項謎語。或許，人類從未如今日這般接近生命的真相，我們將從根本改寫「人類」的意義，眼前正在來臨的是我們將打造的後人類時代。

Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States

A collection of the best science and nature writing from the past year.

An exciting boxed set collection of must-have TED Books for any science reader—from medical professionals to armchair Internet doctors to sci-fi enthusiasts— an engaging and fresh look at the inner an

Accompanying a major exhibition, this stunning survey and important monograph highlights more than two decades’ worth of Lisa Yuskavage’s brilliant and controversial paintings. Internationally acclaim

Edited by Soumyajit Mukherjee and Kieran F. MulchroneDUCTILE SHEAR ZONESFrom Micro- to Macro-scalesThe elucidation of the mechanisms and kinematics of shear zone deformation, at both local and regiona

Interdisciplinary and international in scope, this volume forms the foundations for a Durkheimian sociology of violence, exploring the political anthropology of war, the rapport between power and the