With expert contributions from experienced educators, research scientists and clinicians, Foye's Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike.? This 'gold standard' text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs. Comprehensive coverage of the most cutting edge understanding of drug chemistry, organized and written for ready comprehensionExtensively referenced to allow learners to explore areas of interest in greater depthContemporary focus on drugs viewed by practitioners as the most clinically important in today's health care environmentClinical Significance testimonials that provide a clinician's view of the relevance of medicinal chemistry to practiceScience-practice interface made explicit through drug monographs that highlight ther