One of the main achievements of algebraic geometry over the last 30 years is the work of Mori and others extending minimal models and the Enriques-Kodaira classification to 3-folds. This book, first published in 2000, is an integrated suite of papers centred around applications of Mori theory to birational geometry. Four of the papers (those by Pukhlikov, Fletcher, Corti, and the long joint paper Corti, Pukhlikov and Reid) work out in detail the theory of birational rigidity of Fano 3-folds; these contributions work for the first time with a representative class of Fano varieties, 3-fold hypersurfaces in weighted projective space, and include an attractive introductory treatment and a wealth of detailed computation of special cases.
Why the microbiome--our rich inner ecosystem of microorganisms--may hold the keys to human health.We are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome―the rich ecosystem of microorganisms in and on every human. These microbial hitchhikers may hold the keys to human health. In Gut Feelings, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health. Recent advances in understanding the microbiome and its role in human health dovetail with the development of personalized or “precision” medicine to create treatments and prevention programs targeted to the molecular imprint of an individual. Fasano and Flaherty explore the microbiome's part in such diseases as gut