Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

This 5th edition of this popular graduate textbook, presents a balanced and comprehensive treatment of both time and frequency domain methods with accompanying theory. It includes numerous examples using nontrivial data illustrate solutions to problems such as discovering natural and anthropogenic climate change, evaluating pain perception experiments using functional magnetic resonance imaging, and monitoring a nuclear test ban treaty. The R package 'astsa' has had major updates and the text will reflect those updates. In general, the graphics have been improved. New topics include random number generation, modeling and fitting predator-prey interactions, more emphasis on structural models, testing for linearity, discussion of EM algorithm is more extensive, Bayesian analysis of state space models and MCMC is more extensive (including new scripts in astsa), particle methods are introduced, stochastic volatility coverage is expanded, changepoint detection is introduced (new topic).The

This book describes in detail a research project dedicated to liquid-particle flow using ultrasound techniques. The project consists of theoretical, experimental, data science, finite element modeling, mechanical design and project management components. The objective of the project was to develop the ultrasonic methodology for measurement and characterization of liquid flow containing solid particles, in online (real-time) measurement conditions. The project consists of primary and complementary studies. The primary studies comprise development of the ultrasonic methodology for the simultaneous measurement of the average particle concentration and flow speed parameters. The developed methodology is based on the ultrasonic attenuation spectroscopy and the sound speed measurement methods, supported by data science programs. The complementary studies include acoustic streaming, designing a small-scale rotational test cell with an annular flow channel, testing it for various applications

This book provides an in-depth roadmap for qualitative research methods and data analysis across disciplines using ATLAS.ti. It encompasses and rationalizes key qualitative research concepts and methods with innovative frameworks to enrich the reader’s understanding of qualitative research methods and data analysis. The book contains multiple real-world projects that assist readers in developing conceptual and theoretical knowledge, as well as gaining insights from fieldwork, visualizing data collection, analysis, and methodological interpretations.This easy to use book provides a pragmatic approach to qualitative methods, proficiency in capturing field observations, user-friendly steps to data analysis starting from transcription, preparation of data, reading and identification of quotations, coding, memoing, commenting, code groups, creating smart codes and groups using set, semantic, and proximity operators resulting in generating numerous insightful thematic reports in avariety of

Despite decades of ongoing efforts to improve racial and ethnic diversity in clinical trials, many gaps remain in achieving demographic representation in clinical studies. In May 2024, the National Academies Forum on Drug Discovery, Development, and Translation, in collaboration with the National Cancer Policy Forum, hosted a public workshop to explore system-level changes and initiatives across organizations and sectors to improve representation, data collection, and reporting in clinical trials and progress tracking in the United States.

No dental office should be without this quick-reference drug handbook! Ideal for chairside use by the entire dental team, Mosby’s Dental Drug Reference, 14th Edition, provides guidelines for safe, accurate drug administration. More than 800 drug monographs - including 93 new monographs covering newly released, FDA-approved drugs - make it easy to find the information most relevant to oral healthcare practitioners, including indications and dosages, contraindications, interactions, side effects, serious reactions, and dental-specific drug data. Accompanied by an Evolve website with additional monographs, photos of pathologic conditions, and more, this durable, pocket-sized guide provides the current, concise drug information needed at the point of care.NEW! More than 93 new monographs cover newly released, FDA-approved drugs and provide up-to-date content on the latest drug therapies.NEW! Expanded coverage of ＂Biologic Agents＂ explores their impact on oral health and dental treatment.Du

This reference book compiles the recent advances in computational and experimental modeling to screen and manage Alzheimer's disease. The book discusses how computer-aided drug design approaches reduc

A fresh and funny guide to chemistry using real-life experiments, from TikTok's coolest scientist.Alright BOOM, Big Manny is here to show you how you can become a real-life scientist and create awesome experiments at home using ordinary ingredients.We'll learn some basic (and not-so basic) chemistry tings - from combustion to chromatography (chroma-what-now?).We'll meet the amazing elements that each have their own personalities - from fiery hydrogen to the main man oxygen.And we'll create explosive reactions - from fizzing mixtures to dish soap volcanoes!Let's start experimenting and find out why science is lit, innit.Written by TikTok science sensation Big Manny, this is the perfect book to inspire young scientists aged 8–12.

A hands-on, code-based guide to leveraging Julia in a variety of scientific and data-driven scenarios Key Features: Augment your basic computing skills with an in-depth introduction to JuliaFocus on topic-based approaches to scientific problems and visualisationBuild on prior knowledge of programming languages such as Python, R, or C/C++Purchase of the print or Kindle book includes a free PDF eBook Book Description: Julia is a well-constructed programming language which was designed for fast execution speed by using just-in-time LLVM compilation techniques, thus eliminating the classic problem of performing analysis in one language and translating it for performance in a second.This book is a primer on Julia's approach to a wide variety of topics such as scientific computing, statistics, machine learning, simulation, graphics, and distributed computing.Starting off with a refresher on installing and running Julia on different platforms, you'll quickly get to grips with the core concept

美國凱迪克大獎、Openbook年度童書得主科瑞．R. 塔博震撼新作跟著翠鳥翠翠、小狗賽門和鯰魚小漁，探索橫跨陸海空的生態小宇宙！~~~內容簡介~~~《翠翠掉下去了！》有一天，媽媽不在家，翠鳥翠翠決定開始學飛！即使很害怕，翠翠可不讓恐懼阻撓她學飛的決心。沒想到，她……掉下去了！翠翠能夠扭轉墜落之勢，成功振翅高飛嗎？《更棒的骨頭》小狗賽門叼著一根骨頭來到池塘邊，遇到了一隻長得一模一樣的狗狗。只是他嘴裡叼著的骨頭，比自己的「更棒」！賽門用盡各種方法，企圖想跟水裡的狗交換骨頭：大眼瞪小眼比賽、追尾巴比賽…… 軟硬兼施卻都換不來那根「更棒的」骨頭。究竟小狗賽門怎樣才能交換成功呢？《小漁顛倒游》小漁是一隻快樂的鯰魚，生活在美好的水底世界。水上有各樣的水草搖曳舞動，水下有湛藍的天空和蟲蟲大餐。可是一場交談，令小漁發現了一個天大的祕密……她竟然顛倒了？~~~套書特色~~~►超人氣的互動翻頁設計，身歷其境主角們的酸甜苦辣◄ 來吧來吧！展開雙翅跟著翠翠學習飛翔，與狗狗賽門比賽大眼瞪小眼，也和小漁一起體會180度的翻轉泳姿。科瑞．R. 塔博利用實體書本的開頁，結合天馬行空的轉書創意，打造前所未有的閱讀體驗！►清新自然的風格，刻畫出寓意十足的陸海空小宇宙◄ 作者透過童趣的蠟筆和柔美的水彩筆觸，不只將角色們表現得活靈活現，還期許孩子擁有追夢的勇氣，懂得分享且有同理心，並在面對外界質疑時保有自身的獨特性。

為【劍橋英語教學大師口袋書系列】書籍，內容以「如何有效運用AI提升語言教學」為主軸，提供教學實務上的運用指南與建議，可做為英語教師師培課程用書或課程設計參考書。In this user-friendly book, Nicky Hockly draws on research and her own experience to examine the benefits and challenges of using AI in language teaching. The book provides a range of guidance on good practices in using the technology, with simple tips for applying the learning. It explores some of the key ethical, moral, philosophical and legal questions around using AI and covers topics including accessibility, data ownership and concerns around students cheating. The book also includes support for using AI to help teachers and learners develop. Nicky Hockly's 30 Essentials for Using Artificial Intelligence is an essential guide for teachers of all levels of experience.

Models and Applications of Tourists' Travel Behavior provides an overview of all possible approaches to modeling tourists' travel behavior, helping readers decide which theoretical approach should be chosen depending on the available type of data. It focuses on the connection between traditional travel behavior theories and tourist studies and introduces specific tourist contexts in travel demand modelling. It goes beyond the theoretical background of tourist travel behavior modeling and offers a practical understanding for choosing the right model and sourcing the right data. The book begins with the role of transport in tourist' travel behavior, then employs a literature review to establish the necessary background on the topic. It then goes on to describe theoretical approaches, descriptive approaches, and statistical approaches for modelling. It discusses choice models based on both Stated Preference Data and Revealed Preference Data. It concludes with chapters on machine learning

With an increasing concern of personal data privacy in Hong Kong and around the world, the Office of the Privacy Commissioner for Personal Data (PCPD), Hong Kong publishes this third edition of Personal Data (Privacy) Law in Hong Kong: A Practical Guide on Compliance to provide practical guidance on the law of privacy, and the ways to protect personal data in everyday life. This third edition will guide readers through the recent developments of personal data privacy in the local, regional and global contexts with updates on recent Administrative Appeals Board and Court decisions, and investigation reports and materials from the PCPD. In addition, some most-concerned issues are discussed, such as ethical development and use of AI, the collection and use of personal data by employers during COVID-19, data protection under work-from-home arrangements, data security measures for ICT systems, guidelines on doxxing offences and data breach handling. This book will certainly provide read

While there is a limited data on safety-sensitive professionals, substance use disorders potentially affect pilots and flight attendants at the same rate as the general population - around 15 percent - but due to the high-risk nature of their jobs, aircraft operators are held to a higher standard for substance misuse on the job. To protect the safety of the public and the aviation workforce, the Human Intervention Motivation Study (HIMS) and the Flight Attendant Drug and Alcohol Program (FADAP) were launched to help treat critical aviation workers - pilots and flight attendants, respectively - who misuse substances. In response to a congressional mandate, this new report reviews available evidence on the effectiveness of HIMS and FADAP and offers recommendations for improving these programs.

From the discoveries of the principles of genetic inheritance in the 19th century to the development of the concepts of human molecular genetic disease in the 20th century, the treatment of human disease has been transformed from a focus on symptoms to the goal of correcting underlying genetic defects which are the cause of many human diseases. Here, Theodore Friedmann shows that this scientific revolution in medicine compares in importance to Copernicus's demonstration of the sun-centered order of the planetary system, the 18th and 19th century discoveries of the cellular structure of living systems, germ theory of disease, the invention of anaesthesia, and the discovery that genetic information is stored and transmitted by DNA. The Origin and Development of Genetic Therapies explores the origins and early developmental history of the medical field of gene therapy. Friedmann examines the early failures and increasingly promising clinical "successes" for this new approach to cure genet

Best friends Horse & Buggy's skateboarding shenanigans will have early readers rolling with laughter in this story from Geisel medalist Ethan Long! "Look, Buggy! I have a skateboard." "Do you have a helmet, too?" Horse is ready to try some BIG skateboard tricks . . . and his best friend Buggy has some tricks of his own on how Horse can avoid getting hurt. From tightening helmet straps to bandaging bruised butts, there's no such thing as too much fun with this dynamic duo--especially because they're playing it safe. Ethan Long's expressive, slapstick-style art brings the laugh-out-loud story to life in this early reader that really sticks the landing. Don't miss this hilarious duo's other adventures in Dance, Dance, Dance!, Horse & Buggy Paint It Out!, Horse & Buggy Plant a Seed, and Horse & Buggy on Ice. This book has been officially leveled by using the F&P Text Level Gradient(TM) Leveling System at level E. The award-winning I Like to Read(R) series focuses on gui

Your complete guide to Excel 365, written for newbies all the way to seasoned professionals Neatly organised and written using accessible language, Microsoft Excel 365 Bible contains everything that readers need to know to get up and running quickly with Excel. Covering the numerous updates to Excel 365 since the previous edition was published in 2022, this Second Edition contains many useful examples and tips and tricks that cover all essential aspects of Excel—from the basics, such as navigating the user interface, to more advanced topics, such as creating visualisations and crafting custom functions. Written by an accomplished team of authors with decades of Excel and business intelligence experience, this book explores topics including: Entering and editing worksheet data, with information on data types, formulas, dates, times and other cell contentsBuilding formulas with Excel table objects, correcting common formula errors and using formula variablesWorking with data series, chan

「Experiments in General Chemistry, 4th Edition」是專為大學修習普通化學實驗之一年級學生所編寫的英文實驗教材。內容涵蓋基礎化學、定性與定量分析化學、動力學、電化學與熱力學、有機化學及新穎材料化學等，共18個實驗及18項實驗技能。適合生命科學及材料工程領域學生之學習。實驗教材編寫理念著重於：印證化學原理、基礎實驗技能練習、強化實驗安全與GHS之觀念，並設計合成與性質鑑定兼具之統整型實驗。讓學生由實作中學習科學研究方法，建立探究精神，經由合成新穎材料，如高溫超導體、導電高分子、金奈米粒子等實驗，瞭解科學發展動向，從而增進學生對基礎科學研究之興趣。本書以示範照片搭配實驗步驟、彩色印刷的方式呈現，幫助學生理解及提升學習成效。 Experiments in General Chemistry is a laboratory manual written for first-year students at National Taiwan University. The first edition was published in 2009. It gathers the teaching experiences from the faculty and teaching assistances of the general chemistry education team over the years. The contents cover qualitative and quantitative analytical chemistry, kinetics, thermodynamics, electrochemistry, organic chemistry and novel materials synthesis, with a total of 18 experiments. The core concept is focused on identifying and applying chemical principles, training basic experimental skills, practicing integrated experiments, and building up th

From its origins in 1976, Statistical Techniques in Business and Economics has become a best seller, providing students across the business specialisms with an introductory survey of descriptive and inferential statistics. With a step-by-step approach and clear writing style, any student can learn and succeed in Business Statistics.The new edition includes a focus on the development of basic data analytical skills. Microsoft Excel, Minitab, and MegaStat are used throughout the text to illustrate statistical software analyses, and screen captures are used within the chapters, so the student becomes familiar with the nature of the software output. Additional resources are available online through Connect, with references or links in the text to Excel tutorials that provide users with clear demonstrations using statistical software to create graphical and descriptive statistics and analyses to test hypotheses.What's changed:The Nineteenth Edition made several changes to the flow and organ

With chapters corresponding to the chapters in Linton and Matteson's Medical-Surgical Practical Nursing in Canada, this study guide provides a variety of questions and exercises to help you master the PN's role in Canadian medical-surgical care. Review exercises include fun activities, multiple-choice questions, alternate format questions, and more, all divided by level of difficulty. In the chapters on medical conditions, practical questions help you apply your knowledge directly to real-world patient care. This study guides provides the review and practice you need to prepare for the REx-PN(R) or CPNRE(R) licensure exams! Comprehensive review reflects the latest Canadian Council for Practical Nurse Regulators (CCPNR) national PN competencies (including Ontario and British Columbia). Variety of exercises reinforces learning with matching, multiple-choice, multiple-response, labelling, diagram reading, fill-in-the-blank questions, case studies, and more. Consistent format in each chap

Alzheimer's Disease and Advanced Drug Delivery Strategies compiles under a single volume the most recent advances in drug delivery to the brain as related to AD treatment. The editors recruited scientists from around the world to produce high quality chapters covering not only nanotechnological approaches, but also microsphere, niosomes, and liposomes. Among the topics covered are synthetic molecules, nobiletin, nose to brain delivery, natural biomaterials, cationic nanoformulations, dendrimers, microbubbles, and more. Alzheimer's Disease and Advanced Drug Delivery Strategies is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the brain. Medical & Health Sciences researchers would also benefit from understanding the strategies compiled under this volume.

Best friends Horse & Buggy's skateboarding shenanigans will have early readers rolling with laughter in this story from Geisel medalist Ethan Long! "Look, Buggy! I have a skateboard." "Do you have a helmet, too?" Horse is ready to try some BIG skateboard tricks . . . and his best friend Buggy has some tricks of his own on how Horse can avoid getting hurt. From tightening helmet straps to bandaging bruised butts, there's no such thing as too much fun with this dynamic duo--especially because they're playing it safe. Ethan Long's expressive, slapstick-style art brings the laugh-out-loud story to life in this early reader that really sticks the landing. Don't miss this hilarious duo's other adventures in Dance, Dance, Dance!, Horse & Buggy Paint It Out!, Horse & Buggy Plant a Seed, and Horse & Buggy on Ice. This book has been officially leveled by using the F&P Text Level Gradient(TM) Leveling System at level E. The award-winning I Like to Read(R) series focuses on gui

Early Modern Bodies is a wide-ranging and detailed introduction to a variety of different approaches to and perspectives on bodies in the early modern period, circa 1500–1750.

本書序言Laboratory Manual for Principles of General Chemistry 11th Edition covers two semesters of a general chemistry laboratory program. The material focuses on the lab experiences that reinforce the concepts that not all experimental conclusions are the same and depend on identifying an appropriate experimental procedure, selecting the proper apparatus, employing the proper techniques, systematically analyzing and interpreting the data, and minimizing inherent variables. As a result of ""good"" data, a scientific and analytical conclusion is made which may or may not ""be right,"" but is certainly consistent with the data.Experiments write textbooks, textbooks don't write experiments.A student's scientific literacy grows when experiences and observations associated with the scientific method are encountered. Further experimentation provides additional ""cause & effect"" observations leading to an even better understanding of the experiment.The 11th edition's experiments are informat

In this issue of Clinics in Perinatology, guest editors Drs. Patrick Gallagher and Alex R. Kemperbring their considerable expertise to the topic of Genetics, Newborn Screening, and Inborn Errors of Metabolism. Early recognition through newborn screening is vital for detecting the 6,000 potentially affected newborns each year in the U.S., as timely treatment can prevent early death and long-term morbidity. In this issue, top experts provides important clinical updates in genetic testing, genome sequencing, and newborn screening.Contains 14 practice-oriented topics, including approach to the neonate with suspected inborn error of metabolism; prenatal genetic diagnosis; the future of clinical genomics; genetic testing in the neonate; genetics of congenital heart disease; and moreProvides in-depth clinical reviews of genetics, newborn screening, and inborn errors of metabolism, offering actionable insights for clinical practicePresents the latest information on this timely, focused topic

The world is periodically consumed in violence, in recent years by the Russian invasion of Ukraine, Hamas’ October 7th terrorism in Israel, and by the genocide of Palestinians in Gaza by Israelis in response. To this world-historical situation, this book attempts a curriculum studies response.

In today’s rapidly evolving digital landscape, safeguarding critical data and systems has never been more vital—or more challenging. Systematic Security: A CISO’s Playbook by Timur Qader offers a groundbreaking guide to building a resilient and scalable security practice from the ground up. Blending real-world experience with practical insights, this book lays out a phased approach to security implementation.Timur begins with describing the current state of security and the landscape security professionals find themselves in that offer both opportunity and risk. He goes on to systematically address strategic design, operational efficiency, risk-based modeling, and a rapidly growing regulatory landscape. This essential resource provides step-by-step strategies for implementing a comprehensive security framework. Whether you''re launching a new security program or transforming an existing one, this book delivers actionable insights on governance, compliance, and advanced security operati

More than Civil Engineering: A History of Hong Kong Development (2004-2024) records the history of land formation and infrastructure development in Hong Kong. The Civil Engineering and Development Department is one of the key government institutions responsible for this development. Established in 2004, the Department was formed through the merger of the Territory Development Department and the Civil Engineering Department.

Mindfulness and meditation, practices that are rooted in Buddhism, have become mainstream treatments in counseling and psychotherapy that provide evidence of successful outcomes among secular clients. However, for clients from non-Western backgrounds, dissociating mindfulness practice from the core Buddhist teachings can dilute the transformative power of these practices, causing cultural confusion and lowering the effectiveness of treatment. This book is the first to present Early Buddhist Teachings as a theoretical orientation for the millions of individuals affiliated with Buddhism to create a culturally congruent counseling model. Using original sources in Pāli, it explores key Buddhist concepts such as dependent co-arising, non-self, impermanence, and many others. The authors then compare them with Western psychological concepts, furthering ongoing dialogue between Buddhism and psychotherapy and fostering powerful integrations. This volume also demonstrates how to use the Buddhi

Data Mining: Practical Machine Learning Tools and Techniques, Fifth Edition, offers a thorough grounding in machine learning concepts, along with practical advice on applying these tools and techniques in real-world data mining situations. This highly anticipated new edition of the most acclaimed work on data mining and machine learning teaches readers everything they need to know to get going, from preparing inputs, interpreting outputs, evaluating results, to the algorithmic methods at the heart of successful data mining approaches. Extensive updates reflect the technical changes and modernizations that have taken place in the field since the last edition, including more recent deep learning content on such topics as GANs, transformers, BERT, GPT, VAE, adversarial examples, pre-training and fine-tuning, as well as a comprehensive treatment of ethical and responsible artificial intelligence topics. Authors Ian H. Witten, Eibe Frank, Mark A. Hall, and Christopher J. Pal, along with ne

In 2018, the National Academies released Thriving on Our Changing Planet: A Decadal Strategy for Earth Observation from Space. The decadal survey identified key science questions and prioritized observational needs to advance U.S. efforts in Earth science and support critical applications such as climate modeling and weather prediction. In the past few years, the need for actionable data and better scientific information on Earth's interacting systems has increased in urgency, as global climate change accelerates coupled with increasing numbers of extreme weather events. At the request of NASA, this mid-term assessment evaluates progress and recommends actions to meet decadal survey priorities. This report explores ways that NASA's Earth Science Division can maintain programmatic balance, improve alignment with decadal survey priorities, and prepare for the next decadal survey.

Created by a teacher, Bob Books have been helping children learn to read for more than 40 years. This workbook has more than 90 pages of fun activities to help children strengthen their early phonics skills!With playful stories, silly illustrations, and a phonics approach based on Science of Reading research, Bob Books keep young readers' confidence high, leading to continued success and a love of reading. Your child will soon join the millions of happy kids who say, "I read the whole book!"(R)The 90+ pages of matching activities, letter mazes, writing practice, and more in this fun workbook can be done alongside the Bob Books Stage 1 phonics learn-to-read boxed sets, or by any child who is just starting to sound out (decode) words. Activities gradually increase in difficulty, beginning with activities using only four letter sounds (m, a, t, s) and progressing until all letters of the alphabet have been introduced (except q).90+ pages of activities feature matching activities, letter m

This book is a customized version in Taiwan, and the content is extracted from Chapters 1 to 15 of the book "Introduction to Python Programming and Data Structures, Global Edition, 3rd edition".-- --For introductory courses in Python Programming.A fundamentals first approach to programming helps students create efficient, elegant code.Introduction to Python Programming and Data Structures introduces students to basic programming concepts using a fundamentals-first approach that prepares students to learn object-oriented programming and advanced Python programming. This approach presents programming concepts and techniques that include control statements, loops, functions, and arrays before designing custom classes. Students learn basic logic and programming concepts prior to moving into object-oriented and GUI programming. The content incorporates a wide variety of problems with various levels of difficulty and covers many application areas to engage and motivate students.For a list of

Make Dazzling Crochet Garments and Home Accessories in Record TimeStitch up stunning creations in the space of an afternoon with this extraordinary pattern collection from Angie Bivins, the founder of Whistle and Wool. Utterly achievable and undeniably cute, these 18 incredible patterns were designed with speed in mind. That way, the average crocheter can start and finish entire pieces in the same day, including bigger projects like garments and blankets. Made using thick yarns and easy stitches, each pattern is accessible to fiber artists of all skill levels―but don’t let their simplicity fool you! These clothes, accessories and home décor pieces are so gorgeous you’d never know they took less than a day to make.Whether you’re looking to expand your own hand- made collection or in need of a last-minute present, Angie has you covered. Refresh your wardrobe fast with beautifully crafted pieces like the elegant Embrace Cardigan. Add an extra dose of cozy to your everyday with the luxurio

Uncover History and find out about the Shang dynasty with this fun and humorous guideFounded sometime around 1600 BCE, the Shang Dynasty was governed by a series of about 29 kings over a 600 year period. They were situated along the Yellow River Valley, China, and historians know a lot about their lives from the discovery of the oracle bones, ancient tombs and cities and other artefacts. The Shang Dynasty is known for the invention of early writing, the development of a government, their skill with bronze and their use of the chariot and bronze weapons in warfare.Who were the Shang? Read about their daily lives, what jobs they did, what they made, how they traded and some Chinese folk tales. Find out the answer to questions such as 'how did the Shang wage wars?', 'what were dragon bones?' and 'what did Shang kings do?'Using fun, humorous illustrations, this book offers an insight into the daily life of the Shang people. Ideally suited for readers age 8+Read the other titles in the seri

Embrace your bright side with a daily dose of positivity from the sweetest fruits and the cutest vegetables. You deserve happiness and love. Nothing can stand in your way.You are strong and full of courage. Packed with positive affirmations from lovable lemons, adorable apples, peppy peppers and more, A Little Bit of Positivity gives you just the boost you need with encouraging words and optimism on every page. It's the perfect way to put a smile on your face every day.Filled with adorable illustrations by Jason Cox Guaranteed to give a daily dose of positivity A wonderful gift for loved ones.

The late second through third centuries saw the remarkable confluence of the early church's developing identity, theological understanding and praxis, with a period of opposition and intermittent persecution from the world around it. Theology necessarily engaged with the persecution experience, as the church considered the goodness and providence of God, the Name to be confessed and the purposeful outcome of the antagonism they faced. Ruth Sutcliffe argues that the early fathers' theological understanding of the role of persecution in the Christian life informed their exhortations to individual and communal response, contributing to the church's remarkable survival and growth through this period. Four great thinkers of this era - Clement and Origen of Alexandria and Tertullian and Cyprian of Carthage - each have much to contribute to a theological understanding of Christian persecution, and Sutcliffe explores their widely different perspectives, intellectual milieu and experiences. She

本書通過豐富的實例，詳細介紹R語言在數據分析中的應用，側重於理論方法與應用相結合，實例豐富且通俗易懂，對R語言的各種繪圖方法、與數據表格的連接、基礎統計分析、時間序列分析和多元統計分析應用等方面描述很有自己的特色，詳細介紹了各種統計方法在R語言中的實現過程。 主要內容包括第1章介紹數據分析引論及其環境；第2章介紹R語言數據物件及其類型；第3章介紹R語言數據存儲與讀取；第4章介紹R語言編程；第5章介紹R語言繪圖；第6章介紹R語言描述性統計；第7章介紹R語言參數估計；第8章介紹R語言參數假設檢驗；第9章介紹R語言相關分析、回歸分析與計量檢驗；第10章介紹R語言時間序列分析；第11章介紹R語言主成分分析與因子分析；第12章介紹R語言聚類分析與判別分析；第13章介紹R語言典型相關分析與對應分析。

"《R語言入門與實踐》循序漸進、由淺入深地講解了R語言開發技術，並通過具體實例講解了R語言的各個知識點。本書共分12章，其中第1～2章是基礎知識部分，講解了R語言開發的基礎知識，包括R語言基礎、R語言語法基礎；第3～6章是核心語法部分，分別講解了流程控制語句、函數、數據結構、包和環境空間等知識，這部分內容介紹的是R語言中最重要的語法知識；第7～10章是進階提高部分，分別講解了數據輸入和導出、數據處理、繪製可視化圖、R語言和人工智能等知識，這部分內容是R語言開發技術的重點和核心；第11章和第12章是綜合實戰部分，講解了兩個大型案例的實現過程，介紹了R語言在大型商業項目中的應用。《R語言入門與實踐》不僅可以作為R語言初學者的學習用書，也適合有一定R語言基礎的讀者學習，還可以作為高等院校相關專業的教學用書和培訓機構的教材。"

A guide to using the power of storytelling for success in business of all types and sizes, whether you're an online marketer, advertising professional, salesperson in any field, small business owner, independent contractor, or Fortune 500 executiveThe corporate world is flooded with data: spreadsheets, charts, graphs, and yawn-inducing PowerPoint presentations. But human brains are wired for stories. Stories help us make sense of the world. Stories move us in ways that data can't, and a well-told story trumps a mountain of facts and figures. Matthew Dicks has learned the value of storytelling in his career as a novelist, marketing consultant, and award-winning slam storyteller. He's found that the basic principles of effective storytelling are universal and teachable. In Stories Sell, he applies those principles to business communication, guiding readers to craft stories that connect with audiences -- whether a single person or a crowded auditorium. Jam-packed with examples, Stories Se