Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Learn all the super-important skills you need to keep healthy with this new series of books all about early life skills.No matter what grown-ups tell you, being little is hard work; there’s so much to

《English for Everyone Junior: English Dictionary》專為6至9歲設計，收錄1,000個基礎詞彙，並以A-Z排列，搭配全頁插圖，讓孩子同時熟悉字母與單字。每個詞都置於情境插圖與對話中，幫助理解並強化記憶。隨書附有免費音檔與App，涵蓋單字、片語與歌曲，方便孩子練習正確發音。每個字母單元皆呈現大小寫，強化字母辨識；書中還設有有趣小知識與補充短語，增加學習趣味。書末另含數字、時間與形狀等主題，功能完整，是孩子英語啟蒙的理想工具書。亮點：收錄1,000個必備詞彙插圖與情境設計，學習更直觀免費音檔與App，發音練習便利額外主題補充，延伸實用性Learning new vocabulary is as easy as ABC with this beautifully illustrated dictionary for children aged 6-9. Featuring 1,000 essential first words and a free audio app, this book is perfect for children who are starting to read and speak English as a second language. Every word in English for Everyone Junior: English Dictionary is illustrated and arranged A-Z to help your child build their vocabulary and learn the English alphabet.Audio for all the words, phrases, and songs featured in the book is available online and via the accompanying app, so children can listen and perfect their pronunciation. At the start of each section, the upper-case and lower-case version of each letter is presented to he

How scientists changed the world, one breakthrough at a time. From the discovery of fire and the invention of the wheel to lunar landings and atoms, this book tells the extraordinary story of science and how it changed our world--one breakthrough at a time. Find out how history's most ingenious and daring scientists solved mysteries that had puzzled the ancient world for millennia, triggering an age of discovery that gave us telescopes, flying machines, steam engines, antibiotics, electricity, radio, space travel, and computers. Discover the amazing men and women who challenged conventional thinking and put their lives at risk to learn about everything from planetary orbits and gold to germs, gunpowder and radioactivity. What's the Point of Science? explains in super-simple terms how science really works and why it brought the world out of the dark ages. It's packed with surprising facts, tales of ingenuity and endeavor, and beautiful hand-drawn illustrations that bring the human story

A fun fact book that answers more than 50 burning questions for young Marvel fans!Discover everything you've always wanted to know about your favorite Super Heroes!How much weight can the Hulk lift? What's the farthest distance Spider-Man can sling a web? Can Iron Man fly faster than a space rocket? Young Marvel Super Hero fans want to know everything about their favorite characters from how hard Thor can slam his hammer to the size of the smallest hole Wasp can fly through―and much more.Whether they are obsessed with Marvel comic books or they've only heard about Super Heroes in the playground, young fans will love discovering the fascinating answers to wild, wacky, and wonderful questions about Marvel Super Heroes.

Learn English with this fun course for complete beginners. Simple exercises and lively audio will have you speaking and reading more than 500 words in no time!The perfect introduction to English vocab

Kids will love learning all about the animal kingdom with this spectacular sticker encyclopedia, packed with fascinating facts and more than 600 stickers! By choosing the sticker that fits in each spa

You may not realize it, but math controls just about everything in our world.From cracking codes to winning game shows, from predicting comets to solving crimes, this unique book reveals where our mos

Get ready for festive fun in a galaxy far, far away! Build a snow-droid. Add some festive sparkle to favourite LEGO (R) Star Wars (TM) characters, including Yoda and Darth Vader. Help Han Solo and Che

A frightfully fun LEGO (R) sticker book with more than 1000 Halloween-themed stickers. Step into the spine-chilling world of LEGO models that go bump in the night. DK's Halloween! Ultimate Sticker Co

Dive into our planet's largest and least explored world in this stunning encyclopedia of whales, waves, wrecks, wind farms, and everything oceanic!Using 3D illustrations and a level of detail you can'

This fun first board book shows it's never too early - or late! - to learn about big ideas, and build confidence in science. Just like your little one, Baby Robot is a brilliant scientist in the mak

Explore the laws and theories of physics in this accessible introduction to the forces that shape our Universe, our planet, and our everyday lives. Using a bold, graphic-led approach The Physics Boo

See how young animals grow and change in the first weeks and months of their lives with this series of animal books for young nature lovers. Everyone loves little animals and this book is a must for fans of cute pets. This elegant book follows baby animals in beautiful, crisp photography through their early lives--from helpless newborns to confident, curious creatures on the cusp of adulthood. Meet a playful puppy, a curious kitten, and a delightful baby rabbit and watch how they grow. A series of photographs shows each animal at different stages in its early life. See a bunny before it grows fur, kittens learn to hunt, and a puppy play with toys. These books are a delight to read aloud to preschool children or for young readers to pick up themselves. A must for all young fans of animals.

A book that helps toddlers adjust to using the potty in a fun and comfortable way. A charming and entertaining board book that helps toddlers adjust to using the potty in a fun and relatable way. Meet twins Johnny and Jasmine. It's time they started to try and use a potty and to wear pants. They HAVE pants, but Johnny just puts his on Teddy while Jasmine uses her potty as a slide for her toys! Follow along with the funny story as Johnny and Jasmine go through the ups and downs of their potty training journey, from getting comfortable with a potty, to positive reinforcement, hygiene, and understanding that accidents happen. Packed with handy tips and charming illustrations, Time To Use The Potty is the perfect way to introduce toilet training to your little one. Potty training has never been so easy - or so much fun!

Discover the rich and complex history of the peoples of Africa, and the struggles and triumphs of Black cultures and communities around the world. With profiles of key people, movements, and events, The Black History Book brings together accounts of the most significant ideas and milestones in Black history and culture. This vital and thought-provoking book presents a bold and accessible overview of the history of the African continent and its peoples - from the earliest human migrations to modern Black communities and the African diaspora. Powerful images and innovative infographics bring to life the stories of the early kingdoms of Ancient Egypt, Nubia, and Carthage; the powerful empires of the Medieval and Early Modern eras; and the struggle against European colonizers. Black history and culture beyond the African continent is also explored in detail - including the Atlantic Slave Trade; the quilombos (slave resistance camps) of Brazil; the Harlem Renaissance and Jazz Age; the "Wind

The simplest guide to astronomy and stargazing!Grasping astronomy has never been easier. The awe of the night sky will soon turn into knowledge of the constellations, planets, and astrological phenomena!Bold graphics and easy-to-understand text make this visual guide the perfect introduction to astronomy and stargazing for those who have little time but a big thirst for knowledge. Inside you'll find:- Simple, easy-to-understand graphics that help to explain astronomy, space, and the night sky in a clear, visual way- The latest astronomical information on black holes, gravitational waves, the origin of the Universe, and the planets of the Solar System- User-friendly star-charts that guide you through the sky using brighter stars as "signposts" to locate harder-to-see objects- Essential advice on the practicalities of stargazing - from observing with the naked eye to using telescopesEach pared-back entry covers the essentials more clearly than ever before.

Explore the magic of holidays at Hogwarts Features Harry Potter minifigure in Yule Ball robes. Enter the festive world of LEGO(R) Harry Potter(TM) and visit Hogwarts for a spellbinding winter holiday. Celebrate the season with your favorite LEGO Harry Potter minifigures and join them for a feast in the Great Hall. Admire the castle's decorations and get ready to hit the dance floor at the Yule Ball. Head to the Gryffindor common room to play a game of wizard chess, warm up in front of a roaring log fire, and join Harry as he exchanges gifts with friends. Sprinkled with festive scenes and the latest LEGO Advent Calendars, sets, and minifigures, this is the perfect gift for young LEGO Harry Potter fans. LEGO Harry Potter: Holidays At Hogwarts comes with a Harry Potter minifigure in Yule Ball robes. (c) & (TM) Warner Bros. Entertainment Inc. Publishing Rights (c) JKR. (s20). (c)2020 The LEGO Group.

Learn more than 1,000 of the most common and useful English phrasal verbs using the effective English for Everyone visual method. Phrasal verbs (two- or three-part verbs such as "put off", "put on", "

This picture word book of 1000 first science words is the perfect STEM book for helping children learn.This book introduces key scientific concepts while broadening children's vocabulary and strengthening their early reading and writing skills. Every picture-packed page is full of things such as sounds, light, senses, and machines, with words for each image. 1000 Words: Science clearly labels each picture, which encourages picture-and-word association and helps early reading. Each topic features questions that ask children to find things on the page or that stimulate thinking, talking, and early science skills. The words have been chosen with the help of a leading educational consultant, and include lots of useful nouns, plus some interesting adjectives, and common verbs. This fun and educational picture word book is a must-have first reference title for parents who are keen to develop their child's language, science, and literacy skills.

Babies and toddlers will fall in love with pandas while flipping through the pages of this interactive early learning book about these adorable animals. Meet the black and white panda family and their

Journey back in time and find out where dinosaurs roamed. This unique children's atlas explores each continent, revealing fossil sites and stories on every map. This atlas is packed with maps of early

Get set for a journey across the globe, visiting every country - from Afghanistan to Zimbabwe - to find out what makes each one unique. Along the way, you'll explore mountains, deserts, forests, and r

Some subjects are too interesting to be left at school! Carry on your love of history at home with Ancient Rome - an activity-packed exploration of people and places in this early empire. Divided into

This book empowers children by providing an affirmation for every single day of the year from January 1 to December 31.I am strong. I am brave. I can handle anything. Using the power of positive think

Take an exclusive backstage tour of the world's most exciting museums and discover their hidden treasures.This behind-the-scenes guide showcases a huge range of incredible artifacts from history and r

This remarkable reference book tells the story of science from earliest times to the present day, taking in everything from ancient Greek geometry to quantum physics, and the wedge to the worldwide web. Exploring science in a thematic, highly approachable manner, each spread takes as its theme a specific event, discovery, invention, experiment, theory, or individual and explains why this subject was so significant in the development of scientific thought and what its impact on history has been. In addition to providing a broad-ranging and comprehensive history of science, the book also explains how science works, employing DK's trademark clarity and visual ingenuity to render tricky scientific subjects easily comprehensible. Science is structured chronologically with five chapters covering major phases in world history from ancient times to the present day, with an eye to the future. Within these chapters, subjects are arranged in discrete spreads, each of which takes a key scientific

You've caught your very first Pok mon What do you do now? Should you groom your Pok mon? What does your Pok mon like to eat?Does your Pok mon need exercise?How many Pok mon should you have? Pok mon need to be looked after and nurtured. From where to find a Snorlax to the treats that your Pikachu will love, learn the secrets to caring for Pok mon with this handy guide. How To Care For Your Pok mon is the perfect gift for any budding Pok mon Trainer. (c) 2021 The Pok mon Company International. (c) 1995 - 2021 Nintendo/Creatures Inc./GAME FREAK inc. TM, (R), and character names are trademarks of Nintendo.

Travel back in time to find out about the fantastical wildlife that lived on Earth before we did.From the first living cells to fearsome dinosaurs and giant mammals, take a journey through prehistory to find out about the supersized, the scary, and the downright bizarre animals and plants that inhabited Earth in ancient times. Broken down by animal or plant type, there are profiles on more than 40 key species. With famous favorites such as mighty Tyrannosaurus and huge woolly mammoths, as well as lesser-known organisms, including five-eyed Opabinia and aeroplane-sized pterosaur Quetzalcoatlus, children won't fail to be captivated by the amazing range of beasts on display. Learn about the primeval world itself and how the Earth has changed over time, why fossils form, and the arrival of early humans. Detailed artworks bring the past to life, while pronunciation guides help with tricky names, and a visual index provides a quick overview of every species in the book. My Book of Dinosaurs

Enjoy the holiday season with this festive LEGO sticker book!Visit a magical LEGO Winter Wonderland. From ice-skating minifigures and twinkling trees to excited elves and even a furry Yeti, get in the

Perfect for holiday story time with little ones, this early learning board book takes a very first look at the traditions and festivities of Hanukkah.From the miracle of the oil, lighting the menorah

Perfect for holiday story time with little ones, this early learning board book takes a very first look at the traditions and festivities of Hanukkah. From the miracle of the oil, lighting the menor

Some subjects are too interesting to be left at school! Carry on your love of geography and Earth sciences at home with Weather - an activity-packed exploration of weather and how it affects our world, including climate change. Divided into sections, the book starts with fast facts on topics including the atmosphere, the Sun, wind, the water cycle, climate change, and forecasting; and the book ends with charts of climate zones and weather record breakers. Using this information, you can complete the puzzles in the main part of the book, plus there are hands-on activities such as making an anemometer to measure wind speed and a rain gauge to measure rainfall.Finally, test your new-found knowledge with the quick quizzes (with answers supplied, but no peeking!). You can keep track of your achievements throughout with a star-chart to fill in every time you finish a page. Note to parents: The Eyewitness Project Book series is devised and written with the expert advice of educational and rea

Some subjects are too interesting to be left at school! Carry on your love of geography at home with Earth - an activity-packed exploration of our planet and the forces that shape it. Divided into sections, the book starts with fast facts on topics including rocks and minerals, oceans, climate, and volcanoes; and the book ends with charts of Earth facts and record breakers. Using this information, you can complete the puzzles in the main part of the book, plus there are hands-on activities such as rock collecting and weather watching.Finally, test your new-found knowledge with the quick quizzes (with answers supplied, but no peeking!). You can keep track of your achievements throughout with a star-chart to fill in every time you finish a page. Note to parents: The Eyewitness Project Book series is devised and written with the expert advice of educational and reading consultants and is designed to appeal to children aged 8 years and up.First published in 2007-2009, this series has been

Some subjects are too interesting to be left at school! Carry on your love of science and anatomy at home with Human Body - an activity-packed exploration of how our bodies work. Divided into sections, the book starts with fast facts on topics including the skeleton, muscles, brain, sense, heart, and digestion; and the book ends with charts of body organ facts and record breakers. Using this information, you can complete the puzzles in the main part of the book, plus there are hands-on activities such as watching your muscles work, testing your reflexes, and seeing how two eyes work together.Finally, test your new-found knowledge with the quick quizzes (with answers supplied, but no peeking!). You can keep track of your achievements throughout with a star-chart to fill in every time you finish a page. Note to parents: The Eyewitness Project Book series is devised and written with the expert advice of educational and reading consultants and is designed to appeal to children aged 8 years

Some subjects are too interesting to be left at school! Carry on your love of science at home with Stars & Planets - an activity-packed exploration of space and astronomy. Divided into sections, the book starts with fast facts on topics including stars, galaxies, planets, the Solar System, the Universe, and space travel; and the book ends with charts of Solar System facts and space record breakers. Using this information, you can complete the puzzles in the main part of the book, plus there are hands-on activities such as drawing your own scale model of the Solar System and creating a lunar eclipse.Finally, test your new-found knowledge with the quick quizzes (with answers supplied, but no peeking!). You can keep track of your achievements throughout with a star-chart to fill in every time you finish a page. Note to parents: The Eyewitness Project Book series is devised and written with the expert advice of educational and reading consultants and is designed to appeal to children a

This colourful pop-up peekaboo book follows adorable little monsters as they hide around the house.The lively, read-aloud rhymes encourage literacy and early learning, while the surprise pop-up scenes

Meet a magical family living in a magical home in Disney's new movie Encanto and in this fun sticker book. Travel to Colombia with this ultimate sticker book, featuring beautiful images and artwork from Disney's new movie Encanto. Discover all the key characters, including Mirabel Madrigal and her family, and encounter the magic of the Encanto. Disney Encanto Ultimate Sticker Book will help kids to relive the wonder of Disney's newest movie. Fun stickering activities will keep kids aged 5-7 entertained for hours and, with more than 100 stickers, there are plenty of extra stickers, too.

This beautifully illustrated children's book takes a close look at the life cycle of water, including how it supports all life forms, how humans harness its power, and why we need to conserve it. Water is essential for life. In fact, 60 percent of an adult human is made up of water We drink it and bathe in it, and thousands of creatures live in it. Yet our planet is running desperately low on fresh water, with less than one percent of the water on Earth available to fuel and feed the current population of 7.5 billion people. So dive into the wonderful world of water and find out how you can save this life-giving substance. From raindrops falling from the sky, to rushing rivers and vast oceans full of animals and plants, water is everywhere. Discover how it affects Earth's weather, through rainstorms, snow flurries, and cyclones, and gives life to animals, plants, and humans. Learn how it is used in growing food and in making clothing, as well as how water travels into our homes at the

Dive into the life-cycle of water and discover how it supports all life forms, how humans harness its power, and why we need to conserve it.From snowflakes falling from the clouds and deep ocean currents to hot springs and water in space, this children's nature book showcases the beauty and power of water in the natural world.Inside the pages of this fascinating science book for kids, you'll discover:- Bite-size facts about inhabitants of freshwater and saltwater- Incredible photographs and illustrations that capture the power of water in nature- Subjects included supports STEM learning- How critical water is to the world we live in, covering national curriculum topics around biology, the natural world, geography, global warming for kids, and much moreThe wonderful world of water awaits! Water is essential for life. We drink it, bathe in it, and thousands of creatures live in it. But we are running desperately low on it. Water Cycles shows children how important keeping hydrated is for

Visit Bob and Ginger the guinea pigs in their garden and learn how they grow delicious fruits and vegetables in this colourful picture book. Bob and Ginger the guinea pigs plant delicious fruit and ve