Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

DK’s best-selling illustrated encyclopedia series explores the fantastical world of myths and legends. Discover stories from myth and legend as you've never seen them before through incredibly detailed 3D illustrations in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs and 3D images will engage children in complex subjects.Find yourself transported to a realm of myth and legend with this perfect gift for anyone who loves stories of gods, monsters and heroes. This all-encompassing myth encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations and retellings of different myths and legends from around the world. Children can explore mythology in a new and exciting way through spectacular computer-generated images of key heroes, gods, monsters and locations. This new book in the

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of science. Learn the ins and outs of science as you’ve never seen it before, through incredibly detailed 3D illustrations, in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs, and 3D images will engage children in complex subjects.This impressively detailed encyclopedia uses awesome illustrations to show biology, chemistry, and physics in the world around us. This all-encompassing science encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations of physics, chemistry, and biology, as well as space exploration, the latest technology, wonderful wildlife, and our amazing bodies. Children can explore science in a new and exciting way. Learn about groundbreaking topics like looking inside a cell,

Set off on an exciting journey to meet the Pokémon of Paldea, in this Level 1 Super Reader!Discover their friendships, special skills, and the awesome mysteries they hope to uncover.The engaging text has been carefully leveled using Lexile so that children are set up to succeed. Colorful Pokémon images, clear vocabulary, and a fun quiz will help young readers build their reading ability, as they uncover the exciting secrets of Paldea.

Discover the secrets of Pokémon battles, in this Level 2 Super Reader!Learn how to catch, train, and get the best out of your Pokémon team. Captain Pikachu and his friends will show you how!The engaging text has been carefully leveled using Lexile so that children are set up to succeed. Colorful Pokémon images, clear vocabulary, and a fun quiz will help young readers build their reading ability as they uncover the exciting secrets of Pokémon.

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of transport. Knowledge Encyclopedia: Transport! uses incredibly detailed 3D illustrations to show children aged 9+ everything they need to know about how vehicles work. Children will find themselves totally absorbed in complex subjects with the Knowledge Encyclopedia series, made clear through engaging explanations, intricate illustrations, vivid photographs, and striking 3D images.Meet hundreds of vehicles that float, fly, or speed across the land, including the record breakers - the fastest, largest, longest, and strangest modes of transportation ever to zoom, sail, or soar. This all-encompassing encyclopedia for kids offers:- A whole collection of facts, charts, timelines, and illustrations that cover a vast range of transportation. - Complex subjects that are explained using amazingly detailed CGIs that entice young readers to dive in and explore.- A visual approach using illustrations, photograp

Meet the sea creatures living on a coral reef! Make reading your superpower with DK's beautiful, leveled nonfiction. Use your reading superpowers to learn all about a beautiful coral reef and the sea animals living there - a high-quality, fun, nonfiction reader - carefully leveled to help children progress. Fishy Tales is a beautifully designed reader all about the fish and other sea animals living on a coral reef. The engaging text has been carefully leveled using Lexiles so that children are set up to succeed. A motivating introduction to using essential nonfiction reading skills. Children will love to find out about the beautiful coral reef and all the sea animals that can be spotted on it.

Let's go outside and discover everything nature has to offer!How many legs does a spider have? Can you help spot the nighttime animals? From ferny, forest floors to white, sandy beaches, babies and toddlers will love journeying through the different environments to discover the variety of wildlife that lives in our surroundings. Each section of this engaging and educational book is dedicated to a different habitat, such as forests and mountains. Bright, colorful photographs illustrate each word, with easy-to-read labels so your little one can sound out the words with you. The interactive book encourages children to match up animals and their homes, and count which animals on the page can fly. This delivers a rounded early learning reading experience, and helps your little one develop early speaking, listening, and observation skills. The book has strong board pages made especially for young children. The chunky tabs along the top and side are easy to grab to help with early motor cont

Let’s meet animals from around the world.What lives at the bottom of the ocean? What are your favorite pets? From creepy-crawlies to massive mammals, babies and toddlers will love discovering which animals squeak, squawk, and oink! Each section of this engaging and educational book is dedicated to different types of animals, such as farm and sea animals, with bright, colorful photography of each species. There are easy-to-read labels so your little one can sound out the words with you. The interactive book encourages children to count the tropical fish, pretend to talk like a parrot, and find the animal with a long trunk. This delivers a rounded early learning reading experience, and helps your little one develop early speaking, listening, and observation skills. The book has strong board pages made especially for young children. The chunky tabs along the top and side are easy to grab to help with early motor control. Preschoolers will quickly recognize the picture on the tab which w

Discover the wonders of our rocky planet!This amazing deck of cards welcomes you to Earth's extraordinary minerals and gems, from sparkling emeralds to igneous rocks formed deep inside the Earth’s molten core. Stunning pictures and fast facts enable you to grasp a wealth of knowledge in a fun way. Each card contains snappy and accessible information, displaying each rock or mineral in dazzling detail. The front of the card shows the rock with a clue of what it is. The back reveals the answer, plus a dataset of essential information, ensuring you can recognize sedimentary from sandstone, metamorphic from marble, and pyrite from pearl. You’ll discover the unique qualities of each material, together with how it is used in art, industry, architecture, and science. You can use the cards to test your own knowledge, or how about using them to play a guessing game, quiz, or competitive comparison game with a friend? Our World in Pictures: Rocks & Minerals Flash Cards are packed with informat

Ideal for home learning, this simple and inspirational book has everything you need to grasp grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to figure out what that poem is really about, or where to begin with your essay?Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language. Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to Be Good at Language Art

Ideal for home learning, this simple and inspirational book has everything you need to get to grips with grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to work out what that poem is really about, or where to begin with your essay? Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language.Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to be Good at En

Imagine if you could travel back in time and walk the streets of the past. Where would you go first? Incredible History turns back time to reveal realistic reconstructions of the most incredible locations and exciting moments in history. You’ll feel the roar of the crowd in the Roman Colosseum, walk the ramparts of the Great Wall of China, and ride the first railways. Each story begins with an archaeological site or artifact. You’ll learn when and how it was discovered, and what it teaches us about how the people who lived at the site might have spent their days. Then, you’ll see the location recreated in jaw-dropping 3D detail. Using archaeological evidence, the people and places of the past will be brought back to life before your very eyes. With each page packed with fantastic facts and extraordinary pictures, Incredible History brings together the best parts of history and archaeology to recreate the entire history of the world.

How did they make that using LEGO® bricks?Find out! Meet the professional builders behind some amazing LEGO® models and learn all about how these creative experts make masterpieces using LEGO bricks.

See how young animals grow and change in the first weeks and months of their lives with this series of animal books for young nature lovers. Everyone loves little animals and this book is a must for fans of cute pets. This elegant book follows baby animals in beautiful, crisp photography through their early lives--from helpless newborns to confident, curious creatures on the cusp of adulthood. Meet a playful puppy, a curious kitten, and a delightful baby rabbit and watch how they grow. A series of photographs shows each animal at different stages in its early life. See a bunny before it grows fur, kittens learn to hunt, and a puppy play with toys. These books are a delight to read aloud to preschool children or for young readers to pick up themselves. A must for all young fans of animals.

A book that helps toddlers adjust to using the potty in a fun and comfortable way. A charming and entertaining board book that helps toddlers adjust to using the potty in a fun and relatable way. Meet twins Johnny and Jasmine. It's time they started to try and use a potty and to wear pants. They HAVE pants, but Johnny just puts his on Teddy while Jasmine uses her potty as a slide for her toys! Follow along with the funny story as Johnny and Jasmine go through the ups and downs of their potty training journey, from getting comfortable with a potty, to positive reinforcement, hygiene, and understanding that accidents happen. Packed with handy tips and charming illustrations, Time To Use The Potty is the perfect way to introduce toilet training to your little one. Potty training has never been so easy - or so much fun!

Discover the rich and complex history of the peoples of Africa, and the struggles and triumphs of Black cultures and communities around the world. With profiles of key people, movements, and events, The Black History Book brings together accounts of the most significant ideas and milestones in Black history and culture. This vital and thought-provoking book presents a bold and accessible overview of the history of the African continent and its peoples - from the earliest human migrations to modern Black communities and the African diaspora. Powerful images and innovative infographics bring to life the stories of the early kingdoms of Ancient Egypt, Nubia, and Carthage; the powerful empires of the Medieval and Early Modern eras; and the struggle against European colonizers. Black history and culture beyond the African continent is also explored in detail - including the Atlantic Slave Trade; the quilombos (slave resistance camps) of Brazil; the Harlem Renaissance and Jazz Age; the "Wind

The simplest guide to astronomy and stargazing!Grasping astronomy has never been easier. The awe of the night sky will soon turn into knowledge of the constellations, planets, and astrological phenomena!Bold graphics and easy-to-understand text make this visual guide the perfect introduction to astronomy and stargazing for those who have little time but a big thirst for knowledge. Inside you'll find:- Simple, easy-to-understand graphics that help to explain astronomy, space, and the night sky in a clear, visual way- The latest astronomical information on black holes, gravitational waves, the origin of the Universe, and the planets of the Solar System- User-friendly star-charts that guide you through the sky using brighter stars as "signposts" to locate harder-to-see objects- Essential advice on the practicalities of stargazing - from observing with the naked eye to using telescopesEach pared-back entry covers the essentials more clearly than ever before.

Explore the magic of holidays at Hogwarts Features Harry Potter minifigure in Yule Ball robes. Enter the festive world of LEGO(R) Harry Potter(TM) and visit Hogwarts for a spellbinding winter holiday. Celebrate the season with your favorite LEGO Harry Potter minifigures and join them for a feast in the Great Hall. Admire the castle's decorations and get ready to hit the dance floor at the Yule Ball. Head to the Gryffindor common room to play a game of wizard chess, warm up in front of a roaring log fire, and join Harry as he exchanges gifts with friends. Sprinkled with festive scenes and the latest LEGO Advent Calendars, sets, and minifigures, this is the perfect gift for young LEGO Harry Potter fans. LEGO Harry Potter: Holidays At Hogwarts comes with a Harry Potter minifigure in Yule Ball robes. (c) & (TM) Warner Bros. Entertainment Inc. Publishing Rights (c) JKR. (s20). (c)2020 The LEGO Group.

Learn more than 1,000 of the most common and useful English phrasal verbs using the effective English for Everyone visual method. Phrasal verbs (two- or three-part verbs such as "put off", "put on", "

This picture word book of 1000 first science words is the perfect STEM book for helping children learn.This book introduces key scientific concepts while broadening children's vocabulary and strengthening their early reading and writing skills. Every picture-packed page is full of things such as sounds, light, senses, and machines, with words for each image. 1000 Words: Science clearly labels each picture, which encourages picture-and-word association and helps early reading. Each topic features questions that ask children to find things on the page or that stimulate thinking, talking, and early science skills. The words have been chosen with the help of a leading educational consultant, and include lots of useful nouns, plus some interesting adjectives, and common verbs. This fun and educational picture word book is a must-have first reference title for parents who are keen to develop their child's language, science, and literacy skills.

Babies and toddlers will fall in love with pandas while flipping through the pages of this interactive early learning book about these adorable animals. Meet the black and white panda family and their

Journey back in time and find out where dinosaurs roamed. This unique children's atlas explores each continent, revealing fossil sites and stories on every map. This atlas is packed with maps of early

Get set for a journey across the globe, visiting every country - from Afghanistan to Zimbabwe - to find out what makes each one unique. Along the way, you'll explore mountains, deserts, forests, and r

Some subjects are too interesting to be left at school! Carry on your love of history at home with Ancient Rome - an activity-packed exploration of people and places in this early empire. Divided into

This book empowers children by providing an affirmation for every single day of the year from January 1 to December 31.I am strong. I am brave. I can handle anything. Using the power of positive think

Take an exclusive backstage tour of the world's most exciting museums and discover their hidden treasures.This behind-the-scenes guide showcases a huge range of incredible artifacts from history and r

Includes exclusive model - Bespin Guard's Cloud CarDiscover five exciting adventures from around the LEGO (R) Star Wars (TM) galaxy. Missions feature your favourite characters, including Rey and Han S

Bring the world of Harry Potter to life at home with more than 50 brilliant building ideas! Conjure your own magical world with more than 50 ideas to inspire your own LEGO (R) Harry Potter (TM) models

Watch as Baby Bunny meets cute baby animals in this early learning lift the flap sound book. An interactive board book that contains five large and sturdy flaps, with a surprise character and sound hi

Using stunning film images from popular Marvel Studios movies, this exciting sticker book for children showcases the adventures of Marvel heroes the Avengers. Meet Earth's Mightiest Heroes - Captain A

More than 80 classic myths retold and explained, from early creation beliefs to classical hero narratives and the recurring theme of the afterlife. The latest title in the bestselling Big Ideas series

This pocket-sized companion is the perfect guide to nearly 200 rocks and minerals. From the igneous, sedimentary and metamorphic rocks, to sparkling minerals, this encyclopedic guide covers vital data

Fourteen incredible 3D printing projects for kids to design and print their own toys, gadgets, models, and ornaments without the need for a 3D printer at home. Using freely available online 3D modelli

Packed with colourful images and clear word labels to help build the foundations of early learning. In this book, your little one will discover kittens and puppies as well as animal sounds and what pe

Packed with colourful images and clear labelling to help build the foundations of early learning. In this book, your little one will discover planes, cars, bicycles, trains and boats. It helps your to

Packed with colourful images to help build the foundation of early learning. In this book, your little one will discover faces, legs, arms and feet. It helps your toddler learn all about the human bod

Discover how to identify flowers, where to find them, and other details about more than 100 flowers from around the world. Compact in size yet brimming with information, An Anthology of Flowers explores a vast variety of blooms, from exotic blossoms to iconic favorites. Learn to easily identify different species using detailed annotations, vivid illustrations, and unique descriptions of each flower. Featuring colorful photographs and vibrant illustrations, this book is a treasure trove for budding botanists, nature enthusiasts, and curious readers seeking an informative flower identification book. Whether you're out exploring or flipping through its pages at home, An Anthology of Flowers is sure to bring the natural world to life.

Join these unlikely partners as they learn how to work together on another adventure to save the day and their city. Part of a new series of official Disney graphic novels!Journey beyond the movies as the charming cast of Zootropolis 2 take on new adventures, which see ZPD officers Hopps and Wilde team up on their mission to make the world a better place! Whatever they are dealing with, Judy and Nick realise that not every case is the biggest, but they are all important. A bold and colourful adventure book for kids aged 5-9:Perfect for early readers, The New Adventures of Disney Zootropolis 2 invites kids to embrace the joy of reading in an engaging graphic novel formatBeautiful illustrations and an engaging story make the entry into reading accessible and funPart of a new series of graphic novels featuring popular Disney characters – don’t miss the rest of the series!Embark on New Adventures with more beloved Disney characters:The New Adventures of Disney Zootropolis 2The New Adventur

Help your child power up their reading skills and learn all about football with this fun-filled non-fiction reader carefully levelled to help children progress. DK Super Readers Level 3: Football will help children to learn all about their favourite game! It is a motivating introduction to using essential non-fiction reading skills, proving ideal for children ready to enter the riveting world of reading. DK Super Readers take children on a journey through the wonderful world of non-fiction: travelling back to the time of dinosaurs, learning more about animals, exploring natural wonders and more, all while developing vital non-fiction reading skills and progressing from first words to reading confidently.The DK Super Readers series can help your child practice reading by:Covering engaging, motivating, curriculum-aligned topics. Building knowledge while progressing Years 4 and 5 reading skills. Developing subject vocabulary on topics such as sports.Boosting understanding and retention th

Find Rosie Reindeer and her cuddly friends hiding behind flaps and popping up from the pages in this delightful book for little ones. Rosie Reindeer wants to go outside to play in the snow. But who can she find to join her and where is her sledge? Babies and toddlers will love lifting the big flaps to play peekaboo with Parker Polar Bear, Peter Penguin, Harry Husky, and Sophie Seal as they get ready to have fun in the snow. Rosie Reindeer finds each of her friends, she wraps up warm, puts on her favorite red wellies, and goes outside. Now it's time for Rosie Reindeer's friends to find her! The lively, read-aloud rhymes in this book encourage literacy and early learning, while the surprise pop-up characters will delight curious preschoolers. With the help of parents or caregivers, toddlers will have fun turning the sturdy board book pages and lifting the flaps to find Rosie Reindeer and her cuddly winter friends. Ideal for interactive preschool play, Pop-up Peekaboo! Reindeer will appea