Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Find out how to use your birth horoscope to enhance and transform every area of your life. In Astrology, you'll see how to cast and read your own birth chart; how to interpret the zodiac signs, the su

This picture book of 1000 first words will broaden young children's vocabulary and strengthen their early reading and writing skills. The inviting pages are filled with pictures, word labels, and simp

This playful preschool activity book will unleash your child's curiosity and creativity as they play their way through amazing STEM projects. Perfect for kids ages 3-6, this early learning children's

Give your toddler a head start with these 16 colourful picture cards, expertly designed to develop early language skills, and ideal for preschool play. With a vibrant image on every card, My First Num

Give your toddler a head start with 16 colourful flashcards, expertly designed to develop early language skills and ideal for preschool play. With a vibrant image on every flashcard, DK's My first Wor

This shiny baby book of first words will help your little one learn all about the colours around them. With bright, clear pictures that have a tactile, raised effect, this board book encourages early

This shiny baby book of numbers will help your little one learn to count to 10. With colourful, clear pictures that have a tactile, raised effect, this board book encourages early learning and makes t

With touch and feel patches and sparkly areas to explore, this baby dinosaur board book encourages early learning, and is just right for sharing with your little one. Inside, on 12 sturdy pages, you m

Make learning first colours, shapes, and words fun for babies with 16 colourful flashcards to develop early language skills. With a vibrant image on every flashcard, these sturdy picture cards are per

Make learning first farm animals, vehicles, and words fun for babies with 16 colourful flashcards to develop early language skills. With a vibrant image on every flashcard, these sturdy picture cards

The ideal first book to introduce opposites to toddlers, My First Opposites is packed with colourful images to help build the foundation of early learning. With colourful, bright pictures of lots of d

The ideal first book to introduce the concept of time to toddlers, My First Day and Night is packed with colourful images to help build the foundation of early learning. With colourful, bright picture

Expand and explore your vocabulary. Discover a whole new vocabulary and never be lost for words again, with this comprehensive and detailed illustrated children's thesaurus, with synonyms and antonyms for more than four thousand main entries. This beautifully illustrated thesaurus for kids aged 9 years old and older is packed with:- A comprehensive, illustrated thesaurus created specifically for young readers and writers- Authoritative content from Collins is given the DK treatment to make the pages lively and the words meaningful for children- Fun and fresh illustrated "word features" to explore and expand on vocabularyThis colourful and insightful thesaurus contains more than four thousand entries, where each entry is supported by a definition and example sentence to help boost a child's confidence in using and choosing words.An imaginative mix of photography and illustration gives the book great visual appeal and is the perfect book for children who enjoy words; or who need a little

A self-study English grammar guide using innovative visual learning methods to make even the trickiest points easy to understand, for the approximately 1 million adults in the United States learning English as a second language.Suitable for English-language learners of all levels, from beginner to advanced, and even experienced English speakers looking for a reminder of key language points,English for Everyone: Grammar Guide is an intuitive way to study English grammar. Clear illustrations put learning points in context and make them easy to remember, and simple graphics and annotated sample sentences break down grammar constructions, making even difficult points easy to follow.English for Everyone: Grammar Guide covers the skills and topics needed for the major global English-language exams, including TOEFL, and is the perfect companion to the English for Everyone course and practice books.Series Overview: English for Everyone series teaches all levels of English, from beginner to adv

Which eagle is the most powerful? How do owls find their prey on the darkest nights? Find out with Eyewitness Eagle and learn about the development, anatomy, mating, and nesting habits of birds of pre

Suitable for new parents, this book helps them record baby's birth and family facts, write about favourite things and early routines, take baby's handprint and footprint, add a lock of baby's hair, an

Packed with images and clear word-labels to encourage early learning, this book helps your toddler learn all about tractors. It encourages children to build vocabulary and language skills and grasp ea

Meet all the animals on the farm with Baby Sparkle, ideal for early learning, introducing simple rhymes and funny animal noises Say baaa to the sheep, cheep cheep with the chick and watch the cat slee

Meet fan favourites Stitch, Angel, Leroy, and Scrump in this awesome glow-in-the-dark sticker activity book, featuring over 100 stickers!Join Stitch and friends in this vibrant glow-in-the-dark sticker book, filled with pictures and facts about fan-favourite characters, along with over 100 glow-in-the-dark stickers to use in the book – or wherever you like!Enjoy some glow-in-the-dark sticker fun with Disney’s Stitch:*MORE THAN 100 STICKERS: Perfect for decorating bags, pencil cases, and other belongings*FULL OF IMAGES, FUN FACTS, & ACTIVITIES: Flip through pages featuring plenty of sticker-filled activities, lively images, and fact-packed information about Stitch and friends*A UNIQUE DISNEY STICKER BOOK FOR KIDS: Perfect for young Disney fans and gift buyers looking for delightful Disney gifts for kidsWith the Disney Stitch Glow in the Dark Ultimate Sticker Book, kids can have a blast with Stitch facts, artwork, and plenty of glow-in-the-dark stickers.

Delight your little one with five pop-up surprises of Toy Story characters! It's playtime with the Toy Story pals! Join Woody, Bo Peep, Buzz Lightyear, Jessie, and their friends. Little hands can lift big flaps and see five peekaboo surprises pop up from the pages, and explore themes of friendship, teamwork, and bravery. The lively, read-aloud rhymes encourage literacy and early learning, while the surprise pop-up scenes will delight curious toddlers. With the help of parents and caregivers, children will have fun turning the sturdy board book pages, guessing what's hiding under each flap, and then lifting the flaps to reveal characters from the Toy Story movie series, and play peekaboo! Ideal for interactive preschool play, Pop-Up Peekaboo! DisneyPixar Toy Story will appeal to both parents and children and is certain to keep little ones entertained time and time again! (c)Disney/Pixar

Go on an amazing journey with The Very Hungry Caterpillar and learn all about the wonders of our extraordinary planet Earth.Beautifully illustrated in Eric Carle's signature style, this first earth encyclopedia is perfect for curious kids aged 5-7 who love to learn about our planet.Travel around the world to explore the continents, learn about different habitats and life forms, unlock the secrets of planet Earth deep below the surface and find out what makes this planet so special in this colourful first reference book about our world.For lovers of The Very Hungry Caterpillar, this children's encyclopedia features:The latest title in the successful Eric Carle Encyclopedias series, with over 155,000 copies sold worldwide.More than 250 illustrations in the iconic style of Eric Carle's classic book The Very Hungry Caterpillar.Key curriculum subjects introduced to children aged 5-7.Each chapter focuses on a different theme, with a new topic every time you turn the page. Bite-size chunks of

Learn about trade and global economic crises in The Economics Book.Part of the fascinating Big Ideas series, this book tackles tricky topics and themes in a simple and easy to follow format. Learn about Economics in this overview guide to the subject, great for novices looking to find out more and experts wishing to refresh their knowledge alike! The Economics Book brings a fresh and vibrant take on the topic through eye-catching graphics and diagrams to immerse yourself in. This captivating book will broaden your understanding of Economics, with:– More than 100 of the greatest ideas in economics– Packed with facts, charts, timelines and graphs to help explain core concepts– A visual approach to big subjects with striking illustrations and graphics throughout– Easy to follow text makes topics accessible for people at any level of understandingThe Economics Book is a captivating introduction to historically important and emergingideas in a field of science that often confuses newcomers,

Dive back in time to discover the unbelievable stories of the past through an exciting new map-view of world history. Explore more than 200 vibrant maps showing the history of every continent in this gripping new view of world history for children aged 9-12. History as it Happened breaks down history into simple, manageable chunks.Watch the rise and fall of great empires and kingdoms, see how physical geography influenced the course of history, and learn how lucrative trade routes of spices and silk have all changed the way our world looks today in this fascinating guide. This exciting history map book for children offers:200 colourful maps telling the story of every continent’s history. A kid-friendly breakdown of history told through maps to explain the roots of world events today.Striking illustrations and photos that will immerse children into the time and place in history. Hundreds of specially commissioned maps guide children through key moments in history or show how things chan

Explore the key milestones in the field of economics broken down clearly and simply with The Economics Book.Learn about economics in this overview guide to the subject, which is brilliant for novices looking to learn more and experts wishing to refresh their knowledge.Part of the fascinating Big Ideas series, this book tackles tricky topics and themes in a simple and easy-to-follow format. The Economics Book brings a fresh, vibrant take on the topic, breaking it down in a visual way through images and diagrams.This book will broaden your understanding of Economics with:Some of the greatest ideas in economicsFacts, charts, timelines and graphs to help explain core conceptsA visual approach to big subjects with illustrations and graphics throughoutEasy-to-follow text making topics accessible for people at any level of understandingThe Economics Book is a captivating introduction to historically important and emerging ideas in a field of science that often confuses newcomers, aimed at adu

Learn about how the world of government and power works in The Politics Book. Part of the fascinating Big Ideas series, this book tackles tricky topics and themes in a simple and easy to follow format. Learn about Politics in this overview guide to the subject, great for novices looking to find out more and experts wishing to refresh their knowledge alike! The Politics Book brings a fresh and vibrant take on the topic through eye-catching graphics and diagrams to immerse yourself in. This captivating book will broaden your understanding of Politics, with: - More than 100 groundbreaking ideas in the history of political thought- Packed with facts, charts, timelines and graphs to help explain core concepts- A visual approach to big subjects with striking illustrations and graphics throughout- Easy to follow text makes topics accessible for people at any level of understanding The Politics Book is a captivating introduction to the world's greatest thinkers and their political big ideas th

Elmo wants to share a special message with his friends. Help him find them one by one, including your little one's favorite characters: Big Bird, Abby Cadabby, Cookie Monster, and Oscar the Grouch. Little hands can lift big flaps and see five peekaboo surprises pop up from the pages while they enhance their social-emotional learning and explore themes of friendship and unconditional love. The lively, read-aloud rhymes encourage literacy and early learning, while the surprise pop-up scenes will delight curious preschoolers. With the help of parents and caregivers, children will have fun turning the sturdy board book pages, guessing what's hiding under each flap, and then lifting the flaps to play peekaboo as they reveal Elmo and his friends. Ideal for interactive preschool play, Pop-Up Peekaboo! Elmo Loves You will appeal to both parents and children, and is certain to keep little ones entertained time and time again. (c) 2024 Sesame Workshop.

Discover the fascinating stories behind 300 species of insects and explore their world. Did you know that insects are essential to life on Earth? Without them we simply couldn't exist – they pollinate our crops, break down dead matter, and play a vital role in our ecosystems. Yet their numbers are plummeting in the face of changing climates, pesticide use, and threats to their essential habitats.This cutting-edge book, which is grounded in the latest research and written by members of the Royal Entomological Society, teaches you all you need to know about bugs, beetles, butterflies and more – revealing how vital they are to us and we are to them. From a look at how insects have been collected for study, to the use of insects in medicines, and their importance in art and literature, this fascinating book knits together science, food, culture and natural history. With advice on spotting insects in a range of habitats, species identification notes, a guide to attracting beneficial insects

A stunning art gallery in a book, art, annotated spans more than 3,000 years of paintings, sculptures, and prints. Combining reproductions of each work of art with precise annotations and visual analysis, it is an expertly curated selection of the finest art ever created. Immerse yourself in this book and learn all about art - how Michelangelo painted nudes, what cubism is, and where abstraction came from.Discover ancient Egyptian frescoes, read the visual clues to Leonardo da Vinci's Last Supper, and find out what inspired Louise Bourgeois and Banksy. In this art book, you will find:Art from all over the world exploring key elements such as composition, colour, technique, and symbolism. Profiles the work of more than 450 artists from across the world and many different cultures, covering every period and major art movement.Art set in its historical context, which makes art, annotated a complete overview of art history. An optional 32-page directory of biographies of all the artists fe

Learn more than 10,000 of the most useful words and phrases in French with this beautifully illustrated dictionary for French-language students. Building on the success of the English for Everyone course books and the Bilingual Visual Dictionary series, the French-English Illustrated Dictionary uses crystal-clear illustrations to show the meaning of over 10,000 words of French vocabulary. The words are shown in a visual context in themed sections covering practical or everyday topics (such as shopping, food, or study), providing learners with all the vocabulary they need for work, travel, and leisure. Learning French vocabulary is even easier with this visually stunning dictionary.

Enchant your little one with 5 pop-up surprises of their favorite Disney Princesses! Whether they find Ariel searching for hidden treasures deep under the sea, Moana on the lookout for a new adventure, or Rapunzel swinging down from her tower to follow her dreams, little ones will encounter a magical surprise with the turn of every page. The lively, read-aloud rhymes encourage literacy and early learning, while the surprise pop-up scenes will delight curious toddlers. With the help of parents and caregivers, they'll have fun turning the sturdy board book pages, guessing what's hiding under each flap, and then lifting the flaps to reveal each Princess, and play peekaboo! Ideal for interactive preschool play, Disney Princess Pop-up Peekaboo! will appeal to both parents and children and is certain to keep little ones entertained time and time again.

Discover where events in the Old and New Testaments took place and see how people lived in Biblical times in this illustrated guide.Take a trip around the Holy Land with this collection of beautifully drawn maps, which show where events from the Bible took place.Introducing The Bible Atlas – a beautifully illustrated guide to the geography, events and people of the Old and New Testaments for children aged 9-12. In illustrated guide, follow the journeys of the patriarchs, view inside Solomon's Temple, witness Jesus' miracles, and see exactly where Paul travelled while spreading the message of Christianity.Dive straight into this pictorial Bible guide for kids, offering:- An illustrated guide to key events of the Old and New Testaments for children.- A variety of maps showing in detail where events from the Bible took place.- An original and retro-feel illustration style combined with modern fonts, which creates a different approach compared to photographic or CGI-based books.As well as

Learn all about sparkling gemstones and eye-catching crystals in this handy reference guide for young readers. From the rarest crystal to the most common stone, gems from around the world are revealed in dazzling detail in this illustrated guide.Discover what exactly crystals and gems are, how they're formed, how to identify them, and how they can be used in everything from microchips to jewelry making. How can a rough diamond become a show-stopping centerpiece? Where does labradorite get its colors? Why are there quartz crystals in clocks and watches? How can crystals be grown in a laboratory? Packed with essential information, this edition is more interactive than ever with new infographics, statistics, and facts. Readers will also get a giant fold-out wall chart packed with crystals and details about their uses, which serves as a useful reference tool on your bedroom or classroom wall. Eyewitness Crystal & Gem is the perfect guide for homework help on crystals or for those who s

Visit the stars and planets and learn all about the universe in this fun-filled activity book.How much do you know about outer space and the wonders of the universe? Find answers to all the questions you have about the stars, galaxies, planets, and beyond, from “ How many galaxies are there in the universe?” to “Are aliens real?,” along with many more that you hadn’t even thought of, in this fascinating book. The reference pages packed with plenty of fascinating facts, fun challenges, quizzes, and puzzles will inspire creativity. Roll the dice and start your voyage to a black hole and return safely to Earth. Answer mind-boggling questions. Draw and color your favorite stars and planets. With lively activities that go hand in hand with the educational material, learning has never been so fun and easy! Perfect for inquisitive, fact-loving kids and little ones crazy about the night sky. The Fact-Packed Activity Book: Space will keep young readers entertained for hours.

DK’s best-selling, richly illustrated encyclopedia series explores planet Earth inside and out. Discover our planet―its place in space, its volcanoes, wild landscapes, deserts and oceans, hurricanes and earthquakes. What’s inside Earth, and why is it so hot under the surface? How did our planet come about, and what did it look like in the beginning? How are mountains formed and why are forests important? What happens when glaciers melt and how can we stop climate change? Explore habitats and ecosystems―inside caves, among enormous redwoods, on the savannas, or deep down under the oceans. This extraordinary encyclopedia fuels your imagination with its jaw-dropping visual approach to explain anything from what keeps Earth in its place to the great diversity of plants, animals, and people who live here, how it is changing and why it is unique. Knowledge Encyclopedia: Earth! covers everything you need to know about Earth in glorious technicolor detail alongside easy explanations and fun

Beautifully illustrated in Eric Carle's signature style, this first encyclopedia is perfect for curious kids who love to learn.Take part in an amazing journey of discovery with the Very Hungry Caterpillar and learn fascinating facts about everything from science and space to animals and dinosaurs. Travel around the world to explore the continents, discover where different animals live, learn all about the people who came before us, and find out how your body works in this colorful and charming first reference book for children aged 5-7. Young learners can find out all about light and sound, the planets in the Solar System, how plants grow, and much, much more in this one-of-a-kind introduction to common core subjects. For lovers of The Very Hungry Caterpillar, this must-have children’s encyclopedia features:Fascinating facts about the world around us ideal for curious young learners Clear images and stunning photography throughout Organized into chapters by theme, including space, geog

The secret world of trees is revealed in this beautiful and absorbing guide to the giants of the plant world. Trees occur naturally throughout the world and have been a part of human history almost as long as humans have existed. Used for shelter, tools, fuel, and food, they also help supply the atmosphere with oxygen and form astonishingly diverse ecosystems, as well as some of the world’s most beautiful landscapes. Now the intricate world of leafy woodlands and abundant rainforests is revealed in this extensive visual guide to trees, exploring their key scientific traits and their ecological importance, as well as their enduring significance in human history and culture. From ancient oaks and great redwoods to lush banyans and imposing kapoks, The Tree Book reveals the anatomy, behaviors, and beauty of these incredible plants and habitats in detail. Combining natural history and a scientific overview with a wider look at the history, uses, symbolism, and mythology of trees, this book

Discover the Earth’s most explosive volcanoes and what an earthquake feels like with this picture-led guide exploring the hot spots of the world. This book tells you everything you need to know about the Earth’s most extraordinary natural forces – from active volcanoes, including Kilauea in Hawaii and Etna in Italy, to devastating earthquakes that have hit San Francisco and Japan. Discover how the eruption of Mount Vesuvius devastated the cities of Pompeii and Herculaneum, but left in its wake remarkably preserved treasures. Find out, too, how dogs can search for survivors in the aftermath of a huge quake. Eyewitness Volcano & Earthquake explores how tectonic plates collide, what causes magma to escape from deep inside Earth, and why eruptions affect our weather. Learn how scientists predict and measure the magnitude of earthquakes, and find out what a volcanologist does. Packed with striking full-color photographs and illustrations of lava flows, pyroclastic clouds, rocks and precious