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Encyclopedia of Toxicology, Fourth Edition is currently the most extensive overview of the multiple areas of toxicology, including the chemical, biological and physical (e.g., radiation) perspectives. Spanning across six volumes, this new edition comprises of over 1100 thoroughly revised chapters, and over 80 brand new entries from leading experts which have all been carefully selected and edited by a world-class editorial board. New areas covered in this release include the bourgeoning field of computational toxicology, the many research applications of alternatives to animal testing, the rise in development and use of consumer products and their effects on populations, the increasing introduction and use of pharmaceutical ingredients and their combinations. Other chapters cover artificial intelligence models of toxicological exposure and effects, extractables and leachables testing, cliimate change and its relation to global warming, flood, drought, etc. and the effects on humans, an

Agrios' Plant Pathology, Sixth Edition is the ultimate reference in the field. Here, Dr. Richard Oliver provides a fully updated table of contents with revised and new chapters and invited contributors from around the globe. Building on his legacy, this new edition is an essential read for students, faculty and researchers interested in plant pathology. Sections outline how to recognize, treat and prevent plant diseases and provide extensive coverage on abiotic, fungal, viral, bacterial, nematode and other plant diseases and their associated epidemiology. A large range of case studies take a deep dive into the genetics and modern management of several plant species.

Omics in Horticulture Crops presents a comprehensive view of germplasm diversity, genetic evolution, genomics, proteomics and transcriptomics of fruit crops (temperate, tropical and subtropical fruits, fruit nuts, berries), vegetables, tuberous crops, ornamental and floricultural crops and medicinal aromatic plants. Information covering phenomics, genetic diversity, phylogenetic studies, genome sequencing, and genome barcoding through the utilization of molecular markers plays an imperative role in the characterization and effective utilization of diverse germplasm are included in the book. This is a valuable reference for researchers and academics seeking to improve cultivar productivity through enhanced genetic diversity while also retaining optimal traits and protecting the growing environment.

Introduction to Food Engineering, Sixth Edition brings a much more in-depth and didactic presentation of classic food engineering topics, such as the relationship of engineering to the chemistry, microbiology, nutrition and processing of foods. The book brings more quantitative analyses and problem-solving content, adding more descriptive topics at the end of each chapter to facilitate teaching and student comprehension. Topics cover engineering fundamentals, principles of food processing and preservation operations, solids handling, microbial bioreactions, inactivation and inhibition of microorganisms, and a brief Introduction to economic considerations and regulations. This approach facilitates comprehensive learning that has proven valuable beyond the classroom as a lifetime professional reference.

Cell Physiology Source Book, Fifth Edition covers a broad range of topics in cell physiology. The book discusses research areas that have become active since the last edition (e.g., aquaporins, apicoplast and other organelles) and broadens its scope to include chronobiology, expansion of receptor/sensory physiology, endocrinology, and other topics such as quorum sensing and taxis. As methods or approaches on performing experiments appear to be very valuable parts of books to which readers tend to frequently refer, expansion of these types of chapters and/or appendices are included in this edition. Applicable to scientists, researchers, postdocs and graduate students across physiological, biochemical, biological and biomedical backgrounds, cell physiology is important for understanding larger organisms and potential advances in biomedicine.

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Cannabis, Volume 5 in the Neurobiology of Addiction series, explores the molecular, cellular and systems in the brain responsible for both nicotine and marijuana addiction. This volume includes thorough descriptions of the physiological effects and behavioral effects of nicotine and marijuana addiction. The authors clearly define the neurobiological effects into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage.

The Rise of Chance in Evolutionary Theory: A Pompous Parade of Arithmetic examines the statistical tools and concepts of chance which underlie their applications in natural selection and game theory. The book analyzes the newly recognized relationship between our theoretical apparatus for understanding biological populations and the biological world itself. Over the history of evolutionary biology, including the period from Darwin's early notebooks in 1830 and the publication of R. A. Fisher's Genetical Theory of Natural Selection in 1930, the basis of evolutionary theory has transformed to require considerations of mathematics, statistics and chance. This book charts the development of evolutionary theory from its beginnings to today's advanced knowledge of the primary role of chance in biological processes, making it an ideal resource for evolutionary biologists, researchers and academics in evolution and biological statistics.

This Second Edition of Encyclopedia of Soils in the Environment updates and expand the previous version to ensure coverage of topics relevant to current world problems such as population pressure, food security and global change. Since publication of the previous edition there has been a huge change in our ability to carry out bioinformatics related to soil organisms and their functioning. Major developments in next generation DNA sequencing techniques have opened up the ability to identify both the diversity of microbial populations and their functioning. Furthermore, it is allowing the management of microbes within the soil. Imaging is changing our perceptions and improving our knowledge of soil aggregation. This also applies to remote and proximal sensing of laboratory and field soils, which is seeing rapid change. Soil physics is a core area of soil science, but new techniques and technology have increased our understanding of processes. This reference work coves the entire field o

Targeted Genome Engineering via CRISPR/Cas9 in Plants provides in-depth insights into the use of the emerging "CRISPR/Cas9" technology for precise genome editing. This technology has revolutionized plant science research particularly for crop improvement owing to its simplicity and efficiency. Targeted Genome Engineering via CRISPR/Cas9 in Plants provides a wide range of CRISPR/Cas9 gene editing techniques for numerous varieties of plants. Chapters include the latest applications of CRISPR/Cas9 system in connection with abiotic stress, biotic stress, biofortification, yield improvement, disease modelling and prognosis and molecular diagnosis. This book also evaluates various regulatory and ethical aspects that must be considered when implementing the CRISPR/Cas9 approach. This book is a valuable resource for professionals and researchers, as it provides effective CRISPR/Cas9-based strategies for sustainable agriculture and treatment of infectious and non-infectious diseases.

Allosteric Modulation of G Protein-Coupled Receptors reviews fundamental information on G protein-coupled receptors (GPCRs) and allosteric modulation, presenting original research in the area and collectively providing a comprehensive description of key issues in GPCR allosteric modulation. The book provides background on core concepts of molecular pharmacology while also introducing the most important advances and studies in the area. It also discusses key methodologies. This is an essential book for researchers and advanced students engaged in pharmacology, toxicology and pharmaceutical sciences training and research. Many of the GPCR-targeted drugs released in the past decade have specifically worked via allosteric mechanisms. Unlike direct orthosteric-acting compounds that occupy a similar receptor site to that of endogenous ligands, allosteric modulators alter GPCR-dependent signaling at a site apart from the endogenous ligand. Recent methodological and analytical advances have gr

Great American Diseases: Their Effects on the Course of North American History, Second Edition continues the important coverage of significant disease epidemics that have affected North America, ranging from the arrival of Smallpox with the first Europeans to updated information on the COVID-19 pandemic. It includes an introductory chapter on the basic science behind disease, as well as a new chapter on the history of vaccination in the Americas. Subsequent chapters discuss various diseases, their pathogens and their social ramifications through the history of North America, and the book concludes with a new chapter on notable animal disease outbreaks. This easy-to-read volume provides an interesting and engaging introduction to microbiology, immunology, and epidemiology with up-to-date and contemporary outbreak examples, and is a valuable resource for all biomedical students. Useful PowerPoint slides of all figures and text slides for instructors, as well as further reading recommenda

Coffee is one of the premier global traded commodities generating an annual income of approx. USD 200 billion, supporting the livelihoods of nearly 25 million smallholder farmers, and involving approx. 100 million people worldwide in the entire chain of value, from cultivation to the final product for consumption. The coffee crop sustainability is believed to be threatened by the ongoing and future climate changes, which can alter coffee growth, production, and cup quality in many of the actual production regions. The understanding of such impacts, together with the mechanisms underlying the responses of the coffee tree to new environmental conditions, is therefore of utmost importance. This book offers up-to-date information written by eminent coffee researchers worldwide with ultimate goals of increasing coffee production and quality. It deals with multiple aspects of the coffee crop, from plant physiology to genetics and omics in addition to productivity, crop management and bean qu

Fundamentals of Renewable Energy Processes, Fourth Edition provides accessible coverage of clean, safe alternative energy sources such as solar and wind power. Aldo da Rosa's classic and comprehensive

The Mastery of Bile Duct Injury is a comprehensive medical reference that explores various aspects of biliary injuries, encompassing anatomy, causes, classifications, clinical management, and surgical procedures, with a particular focus on complications arising from laparoscopic cholecystectomy. It not only provides a meticulous dissection of biliary injuries but also navigates through the labyrinth of diagnostic modalities and therapeutic approaches, illuminating a path towards enhanced patient care, surgical precision, and the future of research. Through its detailed examination, this authoritative reference serves as an invaluable resource for the complexities of biliary pathology empowering readers to navigate the challenges inherent in hepatobiliary surgery. Beginning with the historical evolution of cholelithiasis and extending to the impact of laparoscopic cholecystectomy, the book provides detailed insights into the intrahepatic and extrahepatic biliary systems, offering a foun

Quantitative Human Physiology: An Introduction, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. The 3rd edition has been revised with the inclusion of a full new unit on The Integument and Integrated Physiology, more and expanded problem sets, and improved illustrations.

Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting. In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive

Differential Equations with Mathematica, Fifth Edition uses the fundamental concepts of the popular platform to solve (analytically, numerically, and/or graphically) differential equations of interest to students, instructors, and scientists. Mathematica's diversity makes it particularly well suited to performing calculations encountered when solving many ordinary and partial differential equations. In some cases, Mathematica's built-in functions can immediately solve a differential equation by providing an explicit, implicit, or numerical solution. In other cases, Mathematica can be used to perform the calculations encountered when solving a differential equation. Because one goal of elementary differential equations courses is to introduce students to basic methods and algorithms so that they gain proficiency in them, nearly every topic covered this book introduces basic commands, also including typical examples of their application. A study of differential equations relies on concep

Approximately 1 in 54 children in the U.S. will be diagnosed with an autism spectrum disorder (ASD) and that number is expected to rise, according to the CDC. Applied Behavior Analysis (ABA) is one of the most common interventions for those with ASD. One of the biggest problems facing the field of ABA-based interventions is ineffectiveness of intervention approaches due to the rigid application of ABA-based interventions. A Progressive Approach to Applied Behavior Analysis: The Autism Partnership Method provides practicing behavior analysts (e.g., BCBA, BCaBA, RBTs) and other clinicians with an in-depth introduction to a Progressive Approach to ABA and how it applies to common teaching methods within ABA-based interventions. This includes research and guidelines for implementing a Progressive Approach to ABA potentially increasing the likelihood of meaningful outcomes for the individuals with ASD. This will become the guide for practitioners on how to implement clinical judgement using

Rivers of North America, Second Edition, expands on the first edition by including new information on the rivers included in the first edition, with the addition of brand new rivers. These new rivers will be the main focus of the new edition. This will expand on the knowledge our readers have on these rivers and will provide a broader comparative approach in understanding both the common and distinct attributes of river networks. The broad geographic approach of Rivers of North America allows for a comparative approach within any river basin/region. For instance, a river in the Ohio River basin that is serves as a model for addressing questions/issues of other rivers in the same basin. The first edition addressed, in detail, the three primary disciplines of river science: hydrology, geomorphology, and ecology. The interactive nature of these disciplines is further expanded on in this new edition, showing how they define the organization of a riverine landscape and the processes within

Applications of Computational Intelligence in Multi-Disciplinary Research provides readers with a comprehensive handbook for applying the powerful principles, concepts and algorithms of Computational

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synt

Handbook on the Toxicology of Metals: Specific Metals, Fifth Edition, Volume II provides complete coverage of individual metals and their compounds. The book emphasizes toxic effects in humans, along

Handbook on the Toxicology of Metals: General Consideration, Fifth Edition, Volume I provides complete coverage of individual metals and their compounds. The book emphasizes toxic effects in humans, a