Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

DK's award winning Eyewitness Video series, now on DVD! Life goes back billions of years to the bubbling cauldron of the early Earth and life's primitive beginnings, chronicling the development of org

Imagine learning to leap, roar, swim, or fly for the first time.Born to Be Wild explores the vast complexities of growing up in the animal kingdom, where everything feels like new. This book goes where no other has to delve into the countless ways baby animals survive in the wild. Alongside gorgeous photographs of baby bears, lions and tigers, marsupials, birds, and marine mammals, it charts the stages from dependency to independence, and looks at why some animals cling to their mothers for many months, while others must learn to run almost as soon as they are born.Informative step-by-step features focus on particular stages of learning, such as how a lion cub learns to hunt. This book focuses on key themes in a young animal’s life: birth and the very first days of life, learning to hunt and feed, senses and communication, habitat and adaptation, and playtime. Full of beautiful pictures and fascinating science, Born to Be Wild reveals the mysteries of how young creatures survive in an

Understand the rules of English grammar with this fun, fully illustrated reference book for children aged 5–9 who are studying English as a foreign language.Make learning grammar fun with this clear, simple and visual guide for children learning English as a foreign language or English as a second language (ESL). Young learners of English will be captivated and engaged by the dynamic visual approach that sets English for Everyone Junior: English Grammar apart from other language materials for children. Attractive illustrations, clear layouts, and simple explanations present and explain the rules of the English language in a way that is easy for younger learners to understand and digest. The grammar covered in this reference book will help children to describe the world around them, talk about their likes and dislikes, ask questions, and form negative sentences. Grammar is first presented in a realistic scene, and then broken down into small chunks that are easy to unders

A comprehensive and accessible visual history of music – from prehistory to the present.Why did jazz go Latin? And how did blues influence rock? Find out how music has shaped the world from prehistory to the present.Classical or rock, everyone has their favorite music style, but how did your top choice come about? Music is a compelling and richly illustrated history of the most unifying art form in the world. Explore the roots of all genres, from chants of the middle ages through the grandeur of the classical period to the modern rhythm of blues, jazz, hip-hop, and pop. Music includes illustrated histories of instruments and listening suggestions for each musical genre. Spectacular galleries display families of instruments from around the world, while special features showcase the evolution of key instruments, such as the piano and the guitar, and profile iconic innovators such as Mozart, Billie Holiday, and David Bowie. Charting every musical revolution, from bone flutes to electronic

ABOUT ENGLISH FOR EVERYONE JUNIOR SIGHT WORDS FLASH CARDSA set of beautifully illustrated sight word flash cards for preschool children; introduces 100 first sight words. Make learning new sight words fun with this beautifully illustrated pack of 100 flash cards. All the featured words have been selected from the Dolch and Fry word lists for children aged 4–5. On one side of each card is an essential sight word (words that frequently appear in text and are best remembered by sight) in large, bold lettering for easy reading. On the reverse, the word is repeated with a simple example sentence and illustration to put the word into context. Children can use the cards to learn the meaning of sight words before memorizing the words and testing their knowledge. Five additional cards are packed with suggestions for educational games and activities. Simple to use and fun, these flash cards are made of sturdy laminated cardboard and are suitable for young hands to play with again

An eye-popping fact book with a LEGO twist – discover amazing information about the world around us with the help of LEGO minifigures and bricks! Did you know a Goliath spider weighs the same as 75 2x4 LEGO bricks? Or that LEGO bricks and minifigures in various forms have travelled to Saturn, Mars, and the International Space Station? And did you know the Taj Mahal gets a mud pack treatment to remove pollution stains? Or that hummingbirds are the only birds that fly backwards? From unbelievable space and nature facts, to mind-boggling inventions and technology trivia, children will be amazed and entertained with incredible information about the LEGO world and our own. ©2022 The LEGO Group.

Discover the past like never before - in LEGO® bricks!Discover the history of the world and get inspired to build your own epic LEGO® models!The book also comes with bricks to make four exclusive LEGO

In this kids' biography, discover the inspiring life story of Mahatma Gandhi, who successfully used his teachings of non-violence to win his country's freedom.Mohandas Karamchand Gandhi was born at a

Covering the essential math concepts learned in the first years of school, Amazing Visual Math brings a whole new dimension to learning. Amazing Visual Math is an interactive hands-on experience that

Six new titles in the top selling My First series that continue our focus on early language development. This large-format novelty book builds on the phenomenal success of the best selling My First s

Introducing super sized science fun in bite-sized guides! With fun, age appropriate experiments and lift the flap conclusions, the I'm a Scientist series explains science in easy to grasp terms with s

Introducing super sized science fun in bite-sized guides! With fun, age appropriate experiments and lift the flap conclusions, the I'm a Scientist series explains science in easy to grasp terms with s

This chunky format, retro-feel encyclopedia reviews 150 of the most incredible cars in motoring history from the earliest to experiments for the future. Each automobile is illustrated and accompanied

Together with LEGO(r) DUPLO(r) hugely popular building-bricks brand for preschoolers-DK brings stories, coloring, stickers, and building fun to the youngest of readers. In Let's Build! cranes, backhoe

Together with LEGO(r) DUPLO(r) hugely popular building-bricks brand for preschoolers-DK brings stories, coloring, stickers, and building fun to the youngest of readers. In On the Farm young readers wi

Trace India’s journey through its space program, from its early skywatchers, the myths and legends, and the dreamers in a newly independent country, to the visionaries who continue to inspire generations to look towards the stars.In 1947, a newly independent India struggled to manage its new borders, limited resources, and a burgeoning population. Almost instinctively, its leaders turned towards the skies, looking up and beyond to see how they could use technology and space to help their people. This wasn’t a new endeavour, however. Skywatchers in ancient India had always looked towards the stars, mapping them, giving them names, and building myths. So, new India turned towards the stars once again - using satellites to help with agriculture, forecast weather, and build better communication. Today, India’s space program has morphed into something larger. The country looks towards the stars―not to sustain itself, but to explore, to reach the final frontier, and to take its own place amo

Find your route to natural wellness with Neal’s Yard Remedies’ expert guide to using medicinal herbs.Essential Herbs offers expert advice and know-how you can trust in this detailed guide, which featu

Ten years after the high-profile kidnapping of two young boys, only one returns home in Harlan Coben’s gripping thriller. A decade ago, kidnappers grabbed two boys from wealthy families and demanded r

The New York Times BestsellerIn 2006 Jamie Tworkowski wrote a story called “To Write Love on Her Arms” about helping a friend through her struggle with drug addiction, depression, and self-injury. The

LEGOR Star WarsR sets and minifigures come to life in this beautiful photography book. Created by Finnish photographer Vesa Lehtimaki using his son's favorite toys, the book features painstaking recre

History tells the story of mankind from prehistory to the present day using a unique visual approach, filled with timelines, images of artifacts, photography, graphics, and more. Now in its third edit

Cook and learn together with Mommy and Me Start Cooking. Full of fun activities such as experiencing food with all five senses, designing dishes, and performing kitchen experiments, plus an introducti

Newly updated, this guide to the company and its bikes presents a comprehensive history from its early days housed in a backyard shed in Milwaukee to the present and includes an overview of 70 bikes l

This all-in-one kit allows fans to build their very own 3D Star Wars paper models. Using step-by-step instructions and the punch-out card-stock model parts, young fans can build Anakin's lightsaber, Y

Reveal, explore, and celebrate the fascinating LEGOr story in The LEGOr Book. From its beginnings in a carpenter's workshop and the development of the first plastic brick, to the group's current posi

Blast Lab Activity Book catapults young readers into the role of scientists, explorers, and inventors. Packed with easy-to-follow yet spectacular experiments, as well as sticker sheets, quizzes, and

Together with LEGO(r) DUPLO(r) hugely popular building-bricks brand for preschoolers-DK brings stories, coloring, stickers, and building fun to the youngest of readers. Children will love the images a

Using simple text and illustrations, explains what podraces are and describes the different types of pilots who race in the Star Wars film.

An addictive guide to how the Earth works uses brainteasers, puzzles, and off-the-wall experiments to explain everything from how ants walk up walls to why the moon doesn't fall out of the sky.

Text and photographs present a description of early humans, their origins, their tools and weapons, how they hunted and foraged for food, and the role of family life, money, religion, and magic.

Kids can’t resist using and reusing the colorful dinosaur stickers in this dino sticker book. A fun, hands-on way to learn about the magnificent creatures that walked the earth before humans existed.

This biography of one of the most famous and recognizable American presidents mark DK's commitment to bringing US history-based biographies to the DK Readers series. In George Washington, the young r

Looks at the development of technology in the use of metals, wood, plastics, and composite materials, and in the fields of manufacturing, farming, communication, design, computing, and medicine.

Ideal for home learning, this simple and inspirational book has everything you need to grasp grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to figure out what that poem is really about, or where to begin with your essay?Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language. Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to Be Good at Language Art

A book that helps toddlers adjust to using the potty in a fun and comfortable way. A charming and entertaining board book that helps toddlers adjust to using the potty in a fun and relatable way. Meet twins Johnny and Jasmine. It's time they started to try and use a potty and to wear pants. They HAVE pants, but Johnny just puts his on Teddy while Jasmine uses her potty as a slide for her toys! Follow along with the funny story as Johnny and Jasmine go through the ups and downs of their potty training journey, from getting comfortable with a potty, to positive reinforcement, hygiene, and understanding that accidents happen. Packed with handy tips and charming illustrations, Time To Use The Potty is the perfect way to introduce toilet training to your little one. Potty training has never been so easy - or so much fun!

So, you want to learn what it takes to be a Jedi? Are you sure?The Star Wars galaxy can be a dangerous place, and becoming a Jedi is not all about using the Force, dueling with lightsabers, lifting X-

Using stunning film images from popular Marvel Studios movies, this exciting sticker book for children showcases the adventures of Marvel heroes the Avengers.Meet Earth's Mightiest Heroes--Captain Ame

Watch as Baby Bunny meets cute baby animals in this early learning lift the flap sound book.An interactive board book that contains five large and sturdy flaps, with a surprise character and sound hid

Develop your child's early learning with DK's My First series, specially designed to captivate a preschooler's attention while laying a foundation for learning. My First books feature bold, bright pho

Design: The Definitive Visual History lays out the complete evolution of design, from its origins in early cultures to the contemporary design — physical and digital — of today. This comprehensive vol