Design And Modeling for Computer Experiments

Managed Entry Agreements and Funding for Expensive Therapies examinesthe concept of MEA, detailing how depreciation of some specific therapies through intangible amortization is unavoidable.

The COVID-19 pandemic has affected the entire world in an unprecedented way and this book provides an overview of the historical facts as well as ongoing approaches to tackle the COVID-19 pandemic. Experts of the respective domains provide details on anti-SARS-COV-2 drug strategies, including repurposing drugs used for other indications and development of novel drugs looking at different approaches to target virus entry and replication. COVID-19 vaccine development based on inactivated and attenuated live virus, protein subunit and peptide-based vaccines and utilization of vaccine candidates based on viral vectors, DNA and RNA are presented for both preclinical studies and clinical trials.Key Features* Explains the background of the COVID-19 pandemic, the current progress in the development of treatments and prevention of COVID-19 including future aspects of dealing with pandemics. * Serves as a timely repository of knowledge on COVID-19 for researchers and medical professionals engage