Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

This book introduces the main theoretical findings related to copulas and shows how statistical modeling of multivariate continuous distributions using copulas can be carried out in the R statistical

This 5th edition of this popular graduate textbook, presents a balanced and comprehensive treatment of both time and frequency domain methods with accompanying theory. It includes numerous examples using nontrivial data illustrate solutions to problems such as discovering natural and anthropogenic climate change, evaluating pain perception experiments using functional magnetic resonance imaging, and monitoring a nuclear test ban treaty. The R package 'astsa' has had major updates and the text will reflect those updates. In general, the graphics have been improved. New topics include random number generation, modeling and fitting predator-prey interactions, more emphasis on structural models, testing for linearity, discussion of EM algorithm is more extensive, Bayesian analysis of state space models and MCMC is more extensive (including new scripts in astsa), particle methods are introduced, stochastic volatility coverage is expanded, changepoint detection is introduced (new topic).The

This book describes in detail a research project dedicated to liquid-particle flow using ultrasound techniques. The project consists of theoretical, experimental, data science, finite element modeling, mechanical design and project management components. The objective of the project was to develop the ultrasonic methodology for measurement and characterization of liquid flow containing solid particles, in online (real-time) measurement conditions. The project consists of primary and complementary studies. The primary studies comprise development of the ultrasonic methodology for the simultaneous measurement of the average particle concentration and flow speed parameters. The developed methodology is based on the ultrasonic attenuation spectroscopy and the sound speed measurement methods, supported by data science programs. The complementary studies include acoustic streaming, designing a small-scale rotational test cell with an annular flow channel, testing it for various applications

This book provides an in-depth roadmap for qualitative research methods and data analysis across disciplines using ATLAS.ti. It encompasses and rationalizes key qualitative research concepts and methods with innovative frameworks to enrich the reader’s understanding of qualitative research methods and data analysis. The book contains multiple real-world projects that assist readers in developing conceptual and theoretical knowledge, as well as gaining insights from fieldwork, visualizing data collection, analysis, and methodological interpretations.This easy to use book provides a pragmatic approach to qualitative methods, proficiency in capturing field observations, user-friendly steps to data analysis starting from transcription, preparation of data, reading and identification of quotations, coding, memoing, commenting, code groups, creating smart codes and groups using set, semantic, and proximity operators resulting in generating numerous insightful thematic reports in avariety of

Most of the research and experiments in the fields of modeling and control systems have spent significant efforts to find rules from various complicated phenomena by principles, observations, measured

This compilation focuses on the theory and conceptualisation of statistics and probability in the early years and the development of young children’s (ages 3-10) understanding of data and chance. It p

This book presents the statistical analysis of compositional data using the log-ratio approach. It includes a wide range of classical and robust statistical methods adapted for compositional data anal

This book covers various multiple-criteria decision making (mcdm) methods for modeling and optimization of advanced manufacturing processes (AMPs). Processes such as non-conventional machining, r

This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radi

This book provides an introduction to the computational and complex systems modeling of the global spreading of infectious diseases. The latest developments in the area of contagion processes modeling

Modeling and Control of Batch Processes presents state-of-the-art techniques ranging from mechanistic to data-driven models. These methods are specifically tailored to handle issues pertinent to

Progress in plant biology relies on the quantification, analysis and mathematical modeling of data over different time and length scales. This book describes common mathematical and computational appr

This introductory textbook explains the concepts and methods of data and error analysis needed for laboratory experiment write-ups, especially physics and engineering experiments. The book contains th

This book presents the R software environment as a key tool for oceanographic computations and provides a rationale for using R over the more widely-used tools of the field such as MATLAB. Kelley prov

This highly practical resource brings new dimensions to the utility of qualitative data in health research by focusing on naturally occurring data. It examines how naturally occurring data complement

This book introduces the ade4 package for R which provides multivariate methods for the analysis of ecological data. It is implemented around the mathematical concept of the duality diagram, and provi

This Brief discusses a unique mechanism to combine historical and archaeological evidence with statistical geodynamic modeling to study the historical development of the Eura region in lower Satakunta

This book presents the latest developments and breakthroughs in fuzzy theory and performance prediction of queuing and reliability models by using the stochastic modeling and optimization theory. The

This book focuses on quantitative survey methodology, data collection and cleaning methods. Providing starting tools for using and analyzing a file once a survey has been conducted, it addresses field

This open access book focuses on trends in educational inequality using twenty years of grade 8 student data collected from 13 education systems by the IEA’s Trends in Mathematics and Science Study (T

This book highlights new methods, algorithms and software for the digital processing and recovery of signals. In addition, it describes a new method for modeling one dimensional and multidimensional s

A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use

This book provides a thoughtful and rigorous guide to coverage modeling, reviewing essential models, solution approaches, and related applications. Since the early developments of the Location Set Cov

This book bridges the current quantitative and qualitative text analyses, using grammar as a crucial source of investigation. Taking data from Czech, an inflected language, in which the most optimal c

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range o

The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatisti

This book enhances the discussion of anthropized soils with photographs of soil profiles and provides general information about soils in Japan, using data on their physical and chemical properties. So

This unique book provides an overview of continuous time modeling in the behavioral and related sciences. It argues that the use of discrete time models for processes that are in fact evolving in cont

This new edition continues to illustrate the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in bioinforma

This book presents new approaches to fixed income modeling and portfolio management techniques. Taking into account the latest mathematical and econometric developments in finance, it analyzes the hed

This book takes an in-depth look at the development of the private education sector in modern China. Readers will find valuable data and materials never before presented in such an accessible and tran

This monograph provides a new perspective on business modeling in small and medium-sized enterprises (SMEs). It builds on the theoretical framework on innovation and revisits the Zahra and George (200

This open access book examines more than two centuries of societal development using novel historical and statistical approaches. It applies the well-being monitor developed by Statistics Netherlands

Using longitudinal data from the Swiss Household Panel to zoom in on continuity and change in the life course, this open access book describes how the lives of the Swiss population have changed in ter

This book describes the development of systems of magnetic resonance imaging using the higher magnetic field strength of 3 tesla, in comparison to the current gold standard of 1.5 tesla. These new sys

This text demonstrates the process of comprehensive applied mathematical modeling through the introduction of various case studies. The case studies are arranged in increasing order of complexity bas

Based on the Judicial Transparency Index Assessment (2019 and 2020) conducted in China by the Institute of Law of the Chinese Academy of Social Sciences, this book summarizes and analyzes the current situation of judicial openness in China, using a sample of 218 courts across the country for the study. The book analyzes the ideological and institutional origins of judicial openness and examines the operation of judicial openness through the practical experience of role replacement. By analyzing evaluation data in the fields of audit information disclosure, trial information disclosure, judicial enforcement data disclosure, and judicial reform data disclosure, the book points out that the current judicial disclosure has made significant progress, but there are still problems such as unclear disclosure standards, insufficient rigidity in disclosure requirements, and the scope of disclosure still needs to be expanded.The book recommends accelerating the disclosure of judicial legislation,

This book analyses the legal approach to personal data taken by different fields of law. An increasing number of business models in the digital economy rely on personal data as a key input. In exchang

This book is designed to be a practical study in infectious disease dynamics. The book offers an easy to follow implementation and analysis of mathematical epidemiology. The book focuses on recent cas

This book highlights the state of the art and recent advances in Big Data clustering methods and their innovative applications in contemporary AI-driven systems. The book chapters discuss Deep Learnin