David Middleton was a towering figure of 20th Century engineering and science and one of the founders of statistical communication theory. During the second World War, the young David Middleton, worki
Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex manage
This book provides a versatile and lucid treatment of classic as well as modern probability theory, while integrating them with core topics in statistical theory and also some key tools in machine lea
Optimization techniques have been widely adopted to implement various data mining algorithms. In addition to well-known Support Vector Machines (SVMs) (which are based on quadratic programming), diffe
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular
High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a
A handbook of the R statistical programming language, this volume provides a roadmap for the R language and programming environment, pointing readers to further resources and documentation.
With an annual growth rate of over 35%, wind is the fastest growing energy source in the world today. As a result of intensive research and developmental efforts, the technology of generating energy f
The numerous vital applications of complementary DNA (cDNA) technology have changed dramatically as the technology has advanced over recent years.? In cDNA Libraries: Methods and Protocols, expert res
In recent decades, infectious diseases, once believed to be fairly contained, have become a vital, resurgent field of research. In Host-Pathogen Interactions: Methods and Protocols, top experts examin
Societal, ethical, and cost-related issues, not to mention the need for sound scientific methods, have led to new and refined methods for the evaluation of health risks associated with neurotoxic comp
Applications of Finite Element Methods for Reliability Studies on ULSI Interconnections provides a detailed description of the application of finite element methods (FEMs) to the study of ULSI interco
Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediat
A great deal of effort is being invested in understanding the molecular mechanisms through which plants interact with pathogenic microbes. In Plant Immunity: Methods and Protocols, expert researcher
This book offers an introduction to the mathematical, probabilistic and numerical methods used in the modern theory of option pricing. The text is designed for readers with a basic mathematical backgr
Complexity in automation- and safety systems in railway as well as automotive applications are dominated more and more by formal description means, methods and tools. Formal techniques provide next to
Wave Turbulence refers to the statistical theory of weakly nonlinear dispersive waves. There is a wide and growing spectrum of physical applications, ranging from sea waves, to plasma waves, to superf
The domain of non-extensive thermostatistics has been subject to intensive research over the past twenty years and has matured significantly. Generalised Thermostatistics cuts through the traditionali
MaxEnt workshops are devoted to Bayesian inference and Maximum Entropy methods in sciences and engineering. This year's meeting was also encompassed all aspects of probabilistic inference such as foun
This handbook presents a comprehensive and up-to-date overview of unprecedented substantive, theoretical, methodological, and statistical developments and insights, and an in-depth examination of tren
The topics of the conference are very timely as the phenomenal advancements of computing facilities have pierced every segment of science, engineering and technology to find solutions of complex probl
This book offers a modern way of dealing with the problems of equilibrium states of Bose systems. Starting with the variation principle of statistical mechanics and the energy-entropy balance principl
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throug
After Karl Joreskog's first presentation in 1970, Structural Equation Modelling or SEM has become a main statistical tool in many fields of science. It is the standard approach of factor analytic and
Here, the authors present modern mathematical methods to solve problems of differential-operator inclusions and evolution variation inequalities which may occur in fields such as geophysics, aerohydro
This book surveys state-of-the-art optimization modeling for design, analysis, and management of wireless networks, such as cellular and wireless local area networks (LANs), and the services they deli
This volume contains the extended version of selected talks given at the international research workshop "Coping with Complexity: Model Reduction and Data Analysis", Ambleside, UK, August 31 – Septemb
Here, the authors present modern mathematical methods to solve problems of differential-operator inclusions and evolution variation inequalities which may occur in fields such as geophysics, aerohydro
Based on a two-semester course aimed at illustrating various interactions of "pure mathematics" with other sciences, such as hydrodynamics, thermodynamics, statistical physics and information theory,
"Kinetics and Dynamics" on molecular modeling of dynamic processes opens with an introductory overview before discussing approaches to reactivity of small systems in the gas phase. Then it examines st
This volume gives a survey on mathematical and computational methods in image registration. During the last year sophisticated numerical models for registration and efficient numerical methods have be
Written from the physicist’s perspective, this book introduces computational neuroscience with in-depth contributions by system neuroscientists. The authors set forth a conceptual model for complex ne
This volume constitutes the proceedings of the Third IFIP WG 8.1 Working Conference on the Practice of Enterprise Modeling, held in Delft, The Netherlands, during November 9-10, 2010. The goal of the
A brand new appendix by Oscar Garcia-Prada graces this third edition of a classic work. In developing the tools necessary for the study of complex manifolds, this comprehensive, well-organized treatme
This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humani
This book presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. It introduces advanced methods in statistics, including how to choose and work with statis
Complex Systems in Finance and Econometrics is an authoritative reference to the basic tools and concepts of complexity and systems theory as applied to an understanding of complex, financial-based bu
Now in its fourth edition, the first part of this book is devoted to the basic material of complex analysis, while the second covers many special topics, such as the Riemann Mapping Theorem, the gamma
This book is the first of a series covering the major topics that are taught in university courses in Theoretical Physics: Mechanics, Electrodynamics, Quantum Theory and Statistical Physics.
This work presents a thorough treatment of boundary element methods (BEM) for solving strongly elliptic boundary integral equations obtained from boundary reduction of elliptic boundary value problems