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Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

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For decades experiments conducted on space stations like MIR and the ISS have been gathering data in many fields of research in the natural sciences, medicine and engineering. The EU-sponsored Ulisse
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出版日:2011/08/09 作者:T. Agami Reddy  出版社:Springer Verlag  裝訂:精裝
Applied Data Analysis and Modeling for Energy Engineers and Scientists fills an identified gap in engineering and science education and practice for both students and practitioners. It demonstrates ho
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出版日:2009/09/29 作者:Helge Toutenburg  出版社:Springer Verlag  裝訂:精裝
This textbook presents the design and analysis of experiments that comprise the aspects of classical theory for continuous response, modern procedures for categorical response, and especially for corr
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Two-dimensional Transition-metal Dichalcogenides
75 折
出版日:2016/08/04 作者:Alexander V. Kolobov; Junji Tominaga  出版社:Springer Verlag  裝訂:精裝
This book summarizes the current status of theoretical and experimental progress in 2 dimensional graphene-like monolayers and few-layers of transition metal dichalcogenides (TMDCs). Semiconducting monolayer TMDCs, due to the presence of a direct gap, significantly extend the potential of low-dimensional nanomaterials for applications in nanoelectronics and nano-optoelectronics as well as flexible nano-electronics with unprecedented possibilities to control the gap by external stimuli. Strong quantum confinement results in extremely high exciton binding energies which forms an interesting platform for both fundamental studies and device applications. Breaking of spatial inversion symmetry in monolayers results in strong spin-valley coupling potentially leading to their use in valleytronics.Starting with the basic chemistry of transition metals, the reader is introduced to the rich field of transition metal dichalcogenides. After a chapter on three dimensional crystals and a descri
優惠:外文好書 優惠價: 75 11137
庫存:1
Stochastic Process Variation in Deep-Submicron CMOs ─ Circuits and Algorithms
75 折
出版日:2013/11/28 作者:Amir Zjajo  出版社:Springer Verlag  裝訂:精裝
One of the most notable features of nanometer scale CMOS technology is the increasing magnitude of variability of the key device parameters affecting performance of integrated circuits. The growth of variability can be attributed to multiple factors, including the difficulty of manufacturing control, the emergence of new systematic variation-generating mechanisms, and most importantly, the increase in atomic-scale randomness, where device operation must be described as a stochastic process. In addition to wide-sense stationary stochastic device variability and temperature variation, existence of non-stationary stochastic electrical noise associated with fundamental processes in integrated-circuit devices represents an elementary limit on the performance of electronic circuits.In an attempt to address these issues, Stochastic Process Variation in Deep-Submicron CMOS: Circuits and Algorithms offers unique combination of mathematical treatment of random process variation, electrical noise
優惠:外文好書 優惠價: 75 4500
庫存:1
Rock Mechanics: For Underground Mining (2004. Corr. 3rd Printing 2006)
90 折
出版日:2004/11/30 作者:B. H. G. Brady; Edwin T. Brown  出版社:Springer Verlag  裝訂:平裝
This new edition has been completely revised to reflect the notable innovations in mining engineering and the remarkable developments in the science of rock mechanics and the practice of rock angineer
優惠價: 9 3850
庫存:1
Targeting Trafficking in Drug Development
90 折
出版日:2018/04/08 作者:Alfredo Ulloa-aguirre (EDT); Ya-xiong Tao (EDT)  出版社:Springer Verlag  裝訂:精裝
Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as wel
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Applying Test Equating Methods ― Using R
90 折
出版日:2017/03/13 作者:Jorge Gonzalez; Marie Wiberg  出版社:Springer Verlag  裝訂:精裝
This book describes how to use test equating methods in practice. The non-commercial software R is used throughout the book to illustrate how to perform different equating methods when scores data are
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Ordered Data Analysis, Modeling and Health Research Methods ― In Honor of H. N. Nagaraja's 60th Birthday
90 折
出版日:2015/12/16 作者:Pankaj K. Choudhary (EDT); Chaitra H. Nagaraja (EDT); Hon Keung Tony Ng (EDT)  出版社:Springer Verlag  裝訂:精裝
This volume presents an eclectic mix of original research articles in areas covering the analysis of ordered data, stochastic modeling and biostatistics. These areas were featured in a conference held
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Primer to Analysis of Genomic Data Using R
90 折
出版日:2015/06/09 作者:Cedric Gondro  出版社:Springer Verlag  裝訂:平裝
Through this book, researchers and students will learn to use R for analysis of large-scale genomic data and how to create routines to automate analytical steps. The philosophy behind the book is to s
優惠價: 9 3392
無庫存
出版日:2015/04/14 作者:Giovanna Scapin (EDT); Disha Patel (EDT); Eddy Arnold (EDT)  出版社:Springer Verlag  裝訂:精裝
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design
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出版日:2015/04/02 作者:Feroz Jameel (EDT); Susan Hershenson (EDT); Mansoor A. Khan (EDT); Sheryl Martin-moe (EDT)  出版社:Springer Verlag  裝訂:精裝
This volume explores the application of Quality by Design (QbD) to biopharmaceutical drug product development. Twenty-eight comprehensive chapters cover dosage forms, liquid and lyophilized drug produ
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出版日:2015/03/12 作者:Giovanna Scapin (EDT); Disha Patel (EDT); Eddy Arnold (EDT)  出版社:Springer Verlag  裝訂:平裝
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design
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Extremophilic Cyanobacteria for Novel Drug Development
90 折
出版日:2014/12/05 作者:Jnanendra Rath; Sikha Mandal  出版社:Springer Verlag  裝訂:平裝
This volume presents recent developments in the novel drug development and potential of extremophilic cyanobacteria. It discusses how these tiny organism originated, produce oxygen that leads to evolu
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This book deals with one of the most novel advances in mathematical modeling for applied scientific technology, including computer graphics, public-key encryption, data visualization, statistical data
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Enzyme Kinetics in Drug Metabolism ― Fundamentals and Applications
90 折
出版日:2014/02/28 作者:Swati Nagar (EDT); Upendra A. Argikar (EDT); Donald J. Tweedie (EDT)  出版社:Springer Verlag  裝訂:精裝
Drug metabolism and transport are very important facets within the discipline of pharmaceutical sciences, with enzyme kinetic concepts utilized regularly in characterizing and modeling the disposition
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出版日:2013/10/31 作者:Radyadour K. Zeytounian  出版社:Springer Verlag  裝訂:精裝
Using both personal and general historical contexts, this book offers an authoritative account of the rational asymptotic modeling approach. It traces the developments in the field from its early begi
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出版日:2013/09/30 作者:Paolo Carbone (EDT); Sayfe Kiaei (EDT); Fang Xu (EDT)  出版社:Springer Verlag  裝訂:精裝
?This book presents a scientific discussion of the state-of-the-art techniques and designs for the modeling, testing and performance analysis of data converters. It presents the outcome of the IWADC w
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Drug Discovery and Evaluation—Safety and Pharmacokinetic Assays
90 折
出版日:2013/02/01 作者:H. G. Vogel (EDT)  出版社:Springer Verlag  裝訂:精裝
-A landmark in the continuously changing world of drugs-Essential reading for scientists and managers in the pharmaceutical industry involved in drug finding, drug development and decision making in t
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出版日:2012/09/29 作者:Asfar S. Azmi (EDT)  出版社:Springer Verlag  裝訂:精裝
Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the
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出版日:2012/08/01 作者:Przemyslaw Ignaciuk; Andrzej Bartoszewicz  出版社:Springer Verlag  裝訂:精裝
Congestion Control in Data Transmission Networks details the modeling and control of data traffic in communication networks. It shows how various networking phenomena can be represented in a consisten
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LC-MS in Drug Analysis
90 折
出版日:2012/07/31 作者:Loralie J. Langman (EDT); Christine L. H. Snozek (EDT)  出版社:Springer Verlag  裝訂:精裝
Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS
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出版日:2012/06/29 作者:Gerhard Klebe  出版社:Springer Verlag  裝訂:精裝
Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form
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出版日:2012/03/02 作者:Thomas Vogt (EDT); Wolfgang Dahmen (EDT); Peter Binev (EDT)  出版社:Springer Verlag  裝訂:精裝
Modeling Nanoscale Imaging in Electron Microscopy presents the recent advances that have been made using mathematical methods to resolve problems in microscopy. With improvements in hardware-based abe
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出版日:2011/03/31 作者:Peter Bonate (EDT)  出版社:Springer Verlag  裝訂:精裝
The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams.? They regard the practical consideration
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出版日:2009/12/11 作者:Carlo Gaetan; Xavier Guyon  出版社:Springer Verlag  裝訂:精裝
Key spatial models for three types of data are discussed in this overview of spatial modeling and statistics. Real-world applications illustrate the concepts and theories described, in addition to pro
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出版日:2009/11/30 作者:David Borsook (EDT); Lino Beccera (EDT); Edward Bullmore (EDT); Richard Hargreaves (EDT)  出版社:Springer Verlag  裝訂:精裝
Drug development today needs to balance agility, speed, and risk in defining probability of success for molecules, mechanisms, and therapeutic concepts. New techniques such as fMRI promise to be part
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出版日:2009/07/01 作者:Godfrey C. Onwubolu (EDT)  出版社:Springer Verlag  裝訂:精裝
The Group Method of Data Handling (GMDH) is a typical inductive modeling method that is built on principles of self-organization for modeling complex systems. However, it is known to often under-perfo
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出版日:2008/12/15 作者:Christian Ritz  出版社:Springer Verlag  裝訂:平裝
R is a rapidly evolving lingua franca of graphical display and statistical analysis of experiments from the applied sciences. Currently, R offers a wide range of functionality for nonlinear regressio
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出版日:2008/03/07 作者:Deepayan Sarkar  出版社:Springer Verlag  裝訂:平裝
R is rapidly growing in popularity as the environment of choice for data analysis and graphics both in academia and industry. Lattice brings the proven design of Trellis graphics (originally develope
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出版日:2008/03/01 出版社:Springer Verlag  裝訂:平裝
This book presents a wide array of methods applicable for reading data into R, and efficiently manipulating that data.In addition to the built-in functions, a number of readily available packages from
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Protein Structure Prediction
90 折
出版日:2007/11/07 作者:Mohammed J. Zaki (EDT); Christopher Bystroff (EDT)  出版社:Springer Verlag  裝訂:精裝
This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the u
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出版日:2006/03/30 作者:J. Wolberg  出版社:Springer Verlag  裝訂:平裝
The preferred method of data analysis of quantitative experiments is the method of least squares. Often, however, the full power of the method is overlooked, and very few books deal with these techniq
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出版日:2005/10/01 作者:Gary Tad Yamaguchi  出版社:Springer Verlag  裝訂:平裝
Dynamic Modeling of Musculoskeletal Motion introduces biomechanists to modern methods of modeling and analyzing dynamic biomechanical systems in three dimensions. Using vector kinematics, the reader i
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Total Least Squares and Errors-In-Variables Modeling ― Analysis, Algorithms and Applications
90 折
出版日:2002/04/01 作者:Sabine van Huffel (EDT); Philippe Lemmerling (EDT)  出版社:Springer Verlag  裝訂:精裝
In response to a growing interest in Total Least Squares (TLS) and Errors-In-Variables (EIV) modeling by researchers and practitioners, well-known experts from several disciplines were invited to prep
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出版日:1994/03/01 作者:Peter Kloeden; Eckhard Platen; Henri Schurz  出版社:Springer Verlag  裝訂:平裝
This book provides an easily accessible, computationally-oriented introduction into the numerical solution of stochastic differential equations using computer experiments. It develops in the reader an
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You Must Be Very Intelligent ― The Phd Delusion
70 折
出版日:2017/07/10 作者:Karin Bodewits  出版社:Springer Verlag  裝訂:平裝
You Must be Very Intelligent is the author’s account of studying for a PhD in a modern, successful university. Part-memoir and part-exposé, this book is highly entertaining and unusually revealing about the dubious morality and desperate behaviour which underpins competition in twenty-first century academia.This witty, warts-and-all account of Bodewits´ years as a PhD student in the august University of Edinburgh is full of success and failure, passion and pathos, insight, farce and warm-hearted disillusionment. She describes a world of collaboration and backstabbing; nefarious financing and wasted genius; cosmopolitan dreamers and discoveries that might just change the world… Is this a smart people’s world or a drip can of weird species? Modern academia is certainly darker and stranger than one might suspect…This book will put a wry, knowing smile on the faces of former researchers. And it is a cautionary parable for innocents who still believe that lofty academia is erected upon mora
優惠:外文優惠70 優惠價: 7 1385
庫存:1
The Power of Geographical Thinking
75 折
出版日:2017/03/10 作者:Clare Brooks (EDT); Graham Butt (EDT); Mary Fargher (EDT)  出版社:Springer Verlag  裝訂:精裝
In this book geography educators from around the globe discuss their research into the power of geographical thinking and consider successful strategies to implement, improve and advance geography edu
優惠:外文好書 優惠價: 75 5400
庫存:1
Re-irradiation ─ New Frontiers
75 折
出版日:2016/11/02 作者:Carsten Nieder (EDT); Johannes Langendijk (EDT)  出版社:Springer Verlag  裝訂:精裝
This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combine
優惠:外文好書 優惠價: 75 7425
庫存:2
Teaching and Learning of Knot Theory in School Mathematics
75 折
出版日:2012/06/27 作者:Akio Kawauchi (EDT); Tomoko Yanagimoto (EDT)  出版社:Springer Verlag  裝訂:精裝
?This book is the result of a joint venture between Professor Akio Kawauchi, Osaka City University, well-known for his research in knot theory, and the Osaka study group of mathematics education, foun
優惠:外文好書 優惠價: 75 3408
庫存:1
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