Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Tells the story of an otter living in the Devonshire countryside which captures the feel of life in the wild as seen through the otter's own eyes.

Beautiful Darkness is the second bewitching instalment in the bestselling love story Beautiful Creatures - a romance that is bound to capture the hearts of Twilight fans everywhere. Some loves are meant to be. Others are cursed .. . One night in the rain, Ethan Wate opened his eyes and fell in love with Lena Duchannes.His life would never be the same. Lena is a Caster and her family is locked in a supernatural civil war: full of darkness and demons. On her sixteenth birthday Lena made a terrifying choice, which now haunts her day and night.And as her seventeenth birthday approaches Lena and Ethan face even greater danger. A Caster and a Mortal can never truly be together. Every kiss is a curse.Ethan's next heartbeat could be his last. It is their curse now . .. *Don't miss the Warner Brothers and Alcon Entertainment blockbuster movie of Beautiful Creatures directed by Richard LaGravenese (P.S. I Love You) and featuring an all star cast including Emma Thompson, Jeremy Irons, Viola Davie

Harry and the dinosaurs love playing in the waves at Water World. But when a big wave knocks them over, they don't think it's quite such fun after all. Harry isn't sure he wants to go in the water aga

"Dinosaur Dreams" is one of the titles in Allan Ahlberg's iconic children's picture book series about skeletons, "Funnybones". Despite being set in a dark dark house, this brightly coloured book is pe

Lots of cats all around the world do exciting things like fly aeroplanes or play the violin - but my cat, an ordinary round-the-house cat, likes to hide in boxes. Children will love joining in with th

Pete is in a bad mood. It's raining and he can't play out. But never fear, Pete's dad has just the idea to cheer Pete up - turn him into a pizza! He kneads the dough, adds oil and tomatoes, and with s

延續手冊形式與誇張敘事，讓孩子在笑聲中體驗「危險學」的第二階段。這次主角Docter Noel要面對的，是一隻看似無害的小狗Napkin，卻可能暗藏危機。從衣櫃中發出的警告、不可理喻的寵物比賽，到假想的吸塵鱷魚，每一頁都結合圖文，玩轉讀者對日常生活的認知與想像力。推薦給喜愛《Diary of a Wimpy Kid》式幽默與創意、渴望在閱讀中大笑的孩子們。Danger is Still Everywhere: Beware of the Dog! Will Docter Noel Zone's second book tell you how to combat a Crocumm? Yes. And reveal the secrets of the world's greatest (and only) Dangerologist? That Too. Has he written it yet? No.Is it because he's hiding in a wardrobe? Maybe. Docter Noel is facing his most terrifying situation Ever - a little dog called Napkin has come to stay. That may not sound particularly dangerous, but every POD (Pupil of Dangerology) knows the only safe pet is a pet rock.So now Docter Noel is hiding in a wardrobe while Napkin wreaks havoc around the Dangerzone. And all the while Docter Noel is supposed to be writing his new Very Important handbook on Dangerology (Level 2). That is until the Pet of the Year (POTY) contest is announced and Docter Noel hatches a plan.There's only one prob

Sue and Nick are best friends who like lots of diffferent things in lots of different colours. Here they show us some of their favourite things from purple hair and all things blue to red cars and red

Every time Mr Archimedes has a bath with his friends, the water overflows. Somebody must be putting extra water in the bath. Is it Kangaroo? Or is it Goat or Wombat? Whoever it is, Mr Archimedes is go

A classic board book edition of the now famous Christmas tale. James builds a snowman in the garden and wakes up in the night to find that it has come to life. He shows the Snowman his house, and in r

Hello! My name is Edie. I am EVER so helpful. In fact I think helping is one of the things i am best at. Edie certainly is a very good helper, whether it's helping Mummy wake up bright and early, help

Hello! My name is Edie. I am EVER so helpful. In fact I think helping is one of the things i am best at. Edie certainly is a very good helper, whether it's helping Mummy wake up bright and early, help

The race is on to reach the final segment of the Mask of Power! Can Kaos be stopped from piecing the Mask together and using it to terrorize Skylands? There's one giggling, gold-slinging gremlin who s

Early one morning a little spider begins to spin her web on a fencepost and she doesn't stop until it is finished...

Scarlett by Cathy Cassidy is an lovely, addictive page-turner for girls aged 9+ I'll be different, I won't break the rules . . . I promise' Scarlett has got herself in trouble so often, her Mu

Intended for babies to help them develop imagination, early-thinking and memory skills.

Are you hungry? The Very Hungry Caterpillar certainly is!As he eats his way through the week help him to count all the fruits and treats by using the GIANT reusable stickers.

Suitable for very young children, this book teaches young children the key differences between animals and the importance of being yourself. It includes books such as "The Very Hungry Caterpillar", "R

Charlie Bucket loves chocolate. And Mr Willy Wonka, the most wondrous inventor in the world, is opening the gates of his amazing chocolate factory to five lucky children. It's the prize of a lifetime!

Boy and Going Solo is the whole of Roald Dahl's extraordinary autobiography in one volume. Reissued in the new Roald Dahl series style. Boy is the story of Roald Dahl's very own boyhood, including tal

Mr Twit is a foul and smelly man with bits of cornflake and sardine in his beard. Mrs Twit is a horrible old hag with a glass eye. They've kept Muggle-Wump monkeys caged in the garden for far too long

Charlie Bucket loves chocolate - and Mr Willy Wonka, the most wondrous inventor in the world, is opening the gates of his amazing chocolate factory to five lucky children. It's the prize of a lifetime

Hairy Maclary from Donaldson's Dairy is the hilarious rhyming classic by Lynley Dodd. Hairy Maclary goes off for a walk in town, followed by doggish friends of all shapes and sizes. One by one they jo

Mr Willy Wonka, the most wondrous inventor in the world, opens his gates of his amazing chocolate factory to five lucky children. Gobstoppers, wriggle sweets and a river of melted chocolate delight aw

Dizzy by Cathy Cassidy is an irresistible story for girls aged 9+ 'I never sleep, the night before my birthday . . . it's the only day of the year I hear from her . . .' Dizzy's mum left when

Angel Cake by Cathy Cassidy is truly sweet and delicious story for girls aged 9+ Anya used to dream of moving to Britain to start a brand-new life. But as she sits in a school where nobody und

GingerSnaps by Cathy Cassidy is a favourite for girls aged 9+ Gone are the days when Ginger was an outsider, always on the fringes of friendship. She's swapped puppy fat and pigtails for make-

Driftwood by Cathy Cassidy is a touching, utterly brilliant novel for girls aged 9+ 'I feel like I'm losing my best mate . . .' Hannah and Joey have been best friends forever - just the two of

Mouse is doing his best to stay out of trouble. Cat is doing her best to land herself in it. They've both had it pretty tough so when they meet by chance they thank their lucky stars. Weird and wonder

This beautiful hardback edition is a special Puffin Classic created in partnership with the world-famous V & A Museum, and has a stunning cover design inspired by the iconic fashion featured in th

This beautiful hardback edition is a special Puffin Classic created in partnership with the world-famous V & A Museum, and has a stunning cover design inspired by the iconic fashion featured in th

This beautiful hardback edition is a special Puffin Classic created in partnership with the world-famous V & A Museum, and has a stunning cover design inspired by the iconic fashion featured in th

The fate of peculiardom hangs in the balance in this epic conclusion to the #1 bestselling Miss Peregrine's Peculiar Children series.The last thing Jacob Portman saw before the world went dark was a t

'If you want to invent something nobody has ever thought of before, you need to read the things that others don't read, look in the spaces other people are not in...'Layla believes she was right to st

The Very Hungry Caterpillar and friends stay awake for a special visitor in this beautiful new lift-the-flap story - perfect for Christmas!In this brand new lift-the-flap story, set on a silent, snowy

Russia in 1938 is a place of great terror. Joseph Stalin is in charge. His Secret Police are everywhere, searching for anyone who might be his enemy. People have no idea who they can trust. Seven-y

It all began with a hot day in June, and a volcano dropping black ash on Moominmamma's washing. Then a crack appeared in the ground, and Moomintroll's toothbrush slipped straight down into the dark an

The must-have second book in the brilliant Lost and Found series from Cathy Cassidy, bestselling author of the Chocolate Box Girls. Forced to flee his home in Syria for safety in England, Sami attempt

The second title in Rick Riordan's Trials of Apollo series - set in the action-packed world of Percy Jackson. The god Apollo, cast down to earth and trapped in the form of a gawky teenage boy as punis

SILLY SAUSAGE!SMELLY PANTS!!NOODLE HEAD!!! Two cheeky little friends argue over a sweetie - and things get a little out of hand in a flurry of silly name-calling that will have children in hysterics.