Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Push, pull and slide the moving mechanisms to meet all your favourite characters from the deep dark wood in this brilliant board book based on the bestselling classic picture book, The Gruffalo - and

An adorable Sing-Along board book story, with five robust board sliders – easy for little hands to use!Each board book comes with a free instrumental and vocal version of the nursery rhyme – simply scan the QR code for little ones to listen and sing along!With bright illustrations this series make the perfect gift for a baby or toddler!Two young friends set out for an exciting summer camping trip. Join in with this favourite song as they settle down for the night in their cosy tent!There are loads of titles to collect . . .Sing Along with Me! The Wheels on the BusSing Along with Me! If You’re Happy and You Know itSing Along with Me! Old Macdonald Had a FarmSing Along with Me! Row, Row, Row Your Boat…and many more!

The most fun, fact-filled series of flap books ever! Children are curious by nature, so they will love these big books of fun explanation. In this title ‘Space’ they’ll enjoy lifting the flaps to find

It was Christmas Eve in Marie’s house. Her parents were having a party and she and her brother, Fritz, were wondering what wonderful present their Godfather would give them this year...This exquisite

The Little Unicorn is scared of the dark. But luckily the fairies can make their magic wands twinkle! As the fairies take the unicorns through their magical land, they spot more and more lights, in th

什麼能讓壞脾氣猴子變不那麼壞脾氣？是一顆球？一根香蕉？一片彩虹？還是一隻戴著毛茸茸假髮的青蛙？不過似乎什麼都不管用，但幸運的是，Jim的好朋友Norman出現了！他可否幫助Jim將那張皺眉的臉翻轉過來呢？Suzanne和Max Lang用簡單的文字和生動傳神的插畫，為幼兒打造了一本幽默又溫馨的讀物，幫助他們學會面對並處理壞心情。In this hilarious original board book for the littlest grumpy monkey, Jim learns that sometimes it's hard to get over a bad case of grumpiness, but having a good friend can help.What can make a grumpy monkey less grumpy? A ball? A banana? A rainbow? How about a frog in a fluffy wig? Nothing seems to work, but fortunately for young readers Jim's frown is finally turned upside down with the help of his good friend Norman.With just a few words and truly expressive artwork Suzanne and Max Lang give toddlers the perfect funny book to help them deal with a grumpy mood.

In this hilarious lift-the-flap board book, a HUNGRY wolf is ready to gobble up whatever animal crosses his path, with a quick “chomp, chomp!” But when he gobbles up one creature who’s a little more c

將經典故事以全新方式呈現。孩子可以推拉翻動頁面，看見鞋匠與小精靈的互動，是啟蒙童話故事與手部動作發展的理想選擇。Push, pull and turn mechanisms bring this classical fairy tale to life. First Stories: The Elves and the Shoemaker is the perfect introduction for young children to this popular tale as they find out about the poor shoemaker who is helped by some diligent elves and how he repays their kindness. This well-loved story is beautifully imagined for a new generation by illustrator Steph Hinton.Collect more books in the First Stories series: Aladdin, Alice in Wonderland, Beauty and the Beast, A Christmas Carol, Cinderella, Doctor Dolittle, Goldilocks and the Three Bears, Hansel and Gretel, Jack and the Beanstalk, The Jungle Book, The Little Mermaid, Little Red Riding Hood, The Nutcracker, Peter Pan, Pinocchio, Puss in Boots, Rapunzel, Sleeping Beauty, Snow White, The Three Little Pigs, The Snow Queen and The Ugly Duckling.

Nature Explorer is full of wildlife fun, perfect for inquisitive children who love to explore. Toddlers can discover and learn about different types of animals and plant life in the garden, pond and woodland. Includes 15 shaped pieces to play with and fit into the big board book, encouraging hand-eye coordination and problem solving skills.

It's all action and excitement in Thomas & Friends: The Runaway Engine Pop-Up! Clear the tracks for the Runaway Engine in this action-packed Thomas book! It's perfect for toddlers and pre-schoolers who love trains and all things Thomas & Friends. With both flaps and a big bold pop-up on the last page, there's plenty to keep children entertained. Thomas likes to go fast, but one day his brakes are jammed, and he can't stop.Oh, no! Can Thomas' Driver help guide him to safety ... or will there be a big CRASH?Young readers will love lifting the flaps to help clear the tracks for Thomas, and seeing the final pop-up surprise! It also acts as a first words book, with labels on key items in each image. Thomas has been teaching children lessons about life and friendship for 75 years.He ranks alongside other beloved characters such as Paddington Bear, Winnie-the-Pooh and Peter Rabbit as an essential part of our literary heritage.

It's Halloween and Spot is ready to celebrate! Join Spot and his friends as they dress up in spooky costumes to go trick-or-treating. Celebrating Halloween is an exciting first experience for little o

Dinosaur fun for little ones! New in the must-have novelty series featuring bright felt aps and a surprise mirror ending.

3, 2, 1 . . . Lift off! Join in and use the flaps to help the busy astronaut put on her spacesuit, launch the rocket and drive the moon buggy. With interactive action-flaps, you can do it too!Each cle

From boats and trucks to trains, limousines and hot air balloons, explore a huge range of different ways to travel in this charming board book. With peep-through holes throughout, there's a fun surpri

Part of the bestselling TouchThinkLearn seriesTouchThinkLearn: Build is a tactile board book with removable--and movable--characters and elements.The movable pieces invite and involve the reader in th

Introduce your baby to first numbers in this gorgeous pop-up book, illustrated by Nila Aye. Based on the popular tale of Cinderella, a simplified story runs through the book for a shared reading exper

First Stories:The Wind in the Willows is the perfect introduction for young children to Kenneth Grahame's classic tale. Push, pull and slide mechanisms bring the story of Mr Toad and his high-speed ad

*pull tabs and humor provide gentle reassurance to young children and reaffirm positive behavior in social situations*Children will recognize feelings and scenarios similar to their own, whether it's

Little Lion needs a haircut! Follow along as he and his dad go to the barber shop in this lighthearted board book from the Hello Genius series.

Turn wheel to mix-and-match different spooky characters in this fun Halloween novelty book.Turn the Wheel: Spooky Pants is a Halloween treat! This hilarious mix-and-match board book has over 30 differ

An exciting introduction to biology, from tiny bacteria to whole ecosystems, and all the living things in between. The book has an awe-inspiring, general knowledge feel and beautiful illustrations.

Help instill a love of bees in little children with this little flap book that explores their world. Peep inside flowers, beehives and under busy bees, to see what they do all day, how honey is made,

Meet Peppa's family in this adorable book collection, perfect for the littlest readers!Inside you'll find four small chunky board books featuring Peppa, George, Mummy Pig and Daddy Pig, which also mak

An exciting board book series that asks deep questions in a wonderfully accessible way.Even little children have big questions about life. Simone de Beauvoir focused much of her work on the concept of

An exciting board book series that asks deep questions in a wonderfully accessible way.Even little children have big questions about life. Socrates believed being truthful and asking questions about t

An adorable Sing-Along board book story, with five robust board sliders – easy for little hands to use!Each board book comes with a free instrumental and vocal version of the nursery rhyme – simply scan the QR code for little ones to listen and sing along!With bright illustrations this series make the perfect gift for a baby or toddler!When a sailor goes for a sail in his boat, he can’t see very much at all. All toddlers will love joining in with the song, and pointing out the things he’s missed!There are loads of titles to collect…Sing Along with Me! The Wheels on the BusSing Along with Me! If You’re Happy and You Know itSing Along with Me! Old Macdonald Had a FarmSing Along with Me! Row, Row, Row Your Boat…and many more!

B is for Breathe, C is for Calm and F is for Feelings in this beautiful ABC book designed to teach very young children the basic concepts of mindfulness and meditation.Baby Loves is a new range of gif

An introduction to classic Marvel superheroes for the youngest superfans!Jump into action with your favorite Marvel superheroes! Learn all about their superpowers, backstories, and alter egos in these

An introduction to classic Marvel superheroes for the youngest superfans!Jump into action with your favorite Marvel superheroes! Learn all about their superpowers, backstories, and alter egos in these

Little readers will love to use the chunky mechanisms to help Bizzy make passes to his teammates and score goals in this robust board book all about playing football. With wonderfully detailed illustrations by Benji Davies, it's perfect for engaging the very young. 書末附有QRCode可以下載本書聲音檔

A simple body scan exercise that adults and toddlers can do together to soothe themselves and get ready for sleep. One of four stylish board books in the Mindful Tots series, designed to help toddlers

This series of bright, slider board books featuring perennially popular nursery rhymes bursts with energy and cheering illustrations. Now in a new format, with refreshed artwork and on white board so colours look lovely and bright. Each book also comes with slider mechanisms, and both an instrumental and vocal version of the nursery rhyme - simply scan the QR code for little ones to listen and sing along!

Join in the fun with this collection of lift-the-flap animal rhymes from the bestselling creator of preschool classic, Dear Zoo.Featuring much-loved classic rhymes 'Little Miss Muffet' and 'Mary Had a

Discover the scientists who changed our world in My First Heroes: Scientists! Push, pull and slide the scenes to find out about Zhang Heng, Isaac Newton, Marie Curie and Rosalind Franklin, and be insp

This series of bright, slider board books featuring perennially popular nursery rhymes bursts with energy and cheering illustrations. Now in a new format, with refreshed artwork and on white board so

Poke your fingers through the holes on each spread to make wiggly legs for energetic babies as they go about their busy day.Whether waking up or eating breakfast, playing in the bath or getting ready

Spend time with your toddler exploring this delightful book of nursery games. Here you’ll find many well-known games, with a sprinkling of modern variations, for every occasion in a young child’s day.

Spend time with your toddler exploring this delightful book of nursery songs. Here you’ll find many well-known songs, with a sprinkling of modern variations, for every occasion in a young child’s day.

Llama Llama visits Grandma and Grandpa Llama!Llama Llama is invited to Grandma and Grandpa's house! And it will be his first night away from home . . . and from Mama. He packs everything he needs and soon he's having fun with Grandpa and Grandma Llama, riding their lawn tractor, helping Grandpa in his workshop, and eating a "different" but delicious dinner. But when Llama Llama goes to unpack his overnight bag, he realizes that he's forgotten a very important item -- Fuzzy Llama is not there!! Suddenly, Llama Llama is very homesick. But Grandpa knows just what to do. He fetches his own special toy from when he was a boy and helps Llama Llama see that he's not alone; he's safe and loved in Grandma and Grandpa's house, too.

Toddlers will love exploring all the wonders of a day at the fair in this chunky, tactile board book. Little hands will thrill at flipping through the uniquely shaped, die-cut pages that overlap to re