The Opnet User Guide for Practical Computer Network Simulation

'This is a brilliant, timely book for everyone - especially when life is vulnerable and volatile - and it has been written by one of the most resilient leaders I know.' - Pete Greig, 24-7 Prayer International & Emmaus Rd Church You'll bounce back How many of us have heard these well-meaning words when faced with mental or physical health challenges, trauma or the loss of dreams? And yet, life's battles can leave us scarred and changed. Why would we want to go back when what we've been through has taught us so much? It's time to bounce forwards instead. 'Nobody is immune from the storms of life. Patrick's book is a lifeboat while the waves are crashing but it is much more than that: Bouncing Forwards is a guide that helps us to navigate through tricky waters so that we become better equipped for the journey of life. It's an honest, wise and practical handbook for growing in resilience. I can't recommend it highly enough.' - Cathy Madavan Speaker, Writer, Broadcaster and Author of Irrep

Educational theory and practice are historically influenced by the view of behavioral psychologists that learning is synonymous with behavior change. Helping People Learn argues for the practical importance of an alternate view, that learning is synonymous with a change in the meaning of experience. Based on the foundations of cognitive psychology and constructivist epistemology, this book presents a science of education that can guide the development of successful and meaningful educational programs. It serves as a sequel to the best-selling Learning How to Learn and includes ideas developed through the author's research and training programs conducted over the past thirty years. It emphasises the power of the knowledge representation tool 'concept maps', designed to facilitate meaningful learning and creativity. This book capitalises on the advances in technology and is of interest to students, professionals and researchers in educational psychology and learning theory.

Educational theory and practice are historically influenced by the view of behavioral psychologists that learning is synonymous with behavior change. Helping People Learn argues for the practical importance of an alternate view, that learning is synonymous with a change in the meaning of experience. Based on the foundations of cognitive psychology and constructivist epistemology, this book presents a science of education that can guide the development of successful and meaningful educational programs. It serves as a sequel to the best-selling Learning How to Learn and includes ideas developed through the author's research and training programs conducted over the past thirty years. It emphasises the power of the knowledge representation tool 'concept maps', designed to facilitate meaningful learning and creativity. This book capitalises on the advances in technology and is of interest to students, professionals and researchers in educational psychology and learning theory.

This popular handbook provides a practical guide to managing common and important problems in the critically ill patient, as well as sufficient background information to enable understanding of the principles and rationale behind the therapy without overloading the reader with detailed basic science. Fully updated throughout, this third edition of Handbook of ICU Therapy includes new chapters on coagulation problems in the critically ill, airway management, electrolyte and metabolic acid/base problems, optimizing antimicrobial therapy, chronic critical illness, recognizing and responding to the deteriorating patient, ICU rehabilitation, palliative care, neurotrauma, the comatose patient, the obstetric patient, endocrine problems, and care of organ donors. Authored by senior clinicians from both sides of the Atlantic, chapters retain the easy-to-read format of previous editions. Aimed particularly at residents and trainees starting out in the ICU or preparing for postgraduate examinatio

This concise and practical atlas is a guide to the often challenging pathological interpretation of needle core biopsies, with a focus on the differential diagnosis of benign and malignant conditions in lymph node core biopsies. A wide range of pathological changes is covered, along with diagnostic problems and pitfalls. Conditions include: specific reactive conditions such as Kikuchi lymphadenitis and Castleman disease, non-specific reactive lymphadenopathy, malignant lymphomas commonly encountered in needle core biopsies and non-lymphoid and metastatic disease. Detailed photomicrographs are used to illustrate each condition, covering both histological appearances and immunohistochemical findings. An illustrative case is included in most sections and additional images can be found on the accompanying DVD-ROM. This atlas is an essential reference for consultants and specialist medical trainees in the fields of haematopathology, pathology and haematology.

Are you involved in making decisions in court, a tribunal, or another formal decision-making environment? This book gives guidance in the skills required to reach and deliver well-structured judicial decisions.The authors (all of whom have extensive judicial and quasi-judicial experience across England and Wales) guide the readers on the skills required at each stage of a hearing, including: ensuring there is a fair hearing; standards and conduct for decision-makers; successful communication; taking into account the needs of vulnerable participants and litigants in person; case management; assessing evidence; and reaching and delivering a well-structured decision.The book includes practical guidance, examples, and short exercises to help the reader engage with the issues discussed and understand the skills required. Having this book to hand will enable you to make effective and fair decisions that inspire confidence.

This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with sleep disorders. There are detailed reviews of new neuroimaging techniques – including CT, MRI, advanced MR techniques, SPECT and PET – as well as image analysis methods, their roles and pitfalls. Neuroimaging of normal sleep and wake states is covered plus the role of neuroimaging in conjunction with tests of memory and how sleep influences memory consolidation. Each chapter carefully presents and analyzes the key findings in patients with sleep disorders indicating the clinical and imaging features of the various sleep disorders from clinical presentation to neuroimaging, aiding in establishing an accurate diagnosis. Written by neuroimaging experts from around the world, Neuroimaging of Sleep and Sleep Disorders is an invaluable resource for both researchers and clinicians including sleep specialists, neurologists, radiologists, psychiatrists, psychologists.

Psychotherapy in Later Life is a practical how-to-guide for psychiatrists, psychologists and mental health workers on choosing and delivering evidence-based psychological therapies to older adults. It covers all the main evidence-based psychological therapies such as cognitive behavioural therapy (CBT) and interpersonal psychotherapy (IPT), as well as specialist topics such as combining psychotherapy with pharmacological treatments, working with diverse populations and individual versus group therapy. The World Health Organization estimates that over the next four decades, the proportion of the world's older adults will nearly double, from twelve percent to twenty-two percent, and that one in five older adults has a diagnosable mental health disorder. Given the increasing number of older adults requiring mental health treatment, incorporating talking therapies into treatment plans is key to tackling issues related to polypharmacy, medication interactions and side effects. Written by ex

The availability of synchrotron x-ray sources and the subsequent developments described in this book have led to substantial progress in our understanding of molecular ordering at liquid interfaces. This practical guide enables graduate students and researchers working in physics, chemistry, biology and materials science to understand and carry out experimental investigations into the basic physical and chemical properties of liquid surfaces and interfaces. The book examines the surfaces of bulk liquids, thin wetting films and buried liquid-liquid interfaces. It discusses experiments on simple and complex fluids, including pure water and organic liquids, liquid crystals, liquid metals, electrified liquid-liquid interfaces and interfacial monolayers of amphiphiles, nanoparticles, polymers and biomolecules. A detailed description of the apparatus and techniques required for these experiments is provided, and theoretical approaches to data analysis are described, including approximate met

Finally, a new kind of business startup book-packed full of practical advice plus essential legal information you really need but don't get in business school or anywhere else! David J. Muchow is a thirty-year business expert, serial entrepreneur, corporate lawyer, and inventor who can help you build a successful startup business. This unique guide, which focuses on both the business and legal aspects of startups, is a must-have for every aspiring entrepreneur, small business owner, startup incubator, student, and business and law schools. In 7 Secret Keys to Startup Success, you will learn: How to cut legal expenses and manage lawyersHow to fire employees and partners without getting suedPatent, trademark and copyright strategies and tricksHow to raise money without SEC problemsHow to avoid the financial "Valley of Death"What "to do" but also "what not to do" to avoid "startup suicide". The book reveals key mistakes that can kill businesses. For example, blogging about your

A straightforward, practical guide to the newest frontier in investment strategycryptofrom #1 New York Times bestselling author and personal finance expert Ric Edelman.Blockchain and bitcoin are here to stayand as the Bank of England stated, this new technology could ';transform the global financial system.' No wonder PWC says blockchain technology will add $2 trillion to the world's $80 trillion economy by 2030. Indeed, blockchain technology and the digital assets it makes possible are revolutionary, the most profound innovation for commerce since the invention of the internet. And yet, the average investorand the investment advisors who manage two-thirds of all their moneyaren't aware of all this, or of the incredible investment opportunities now available. Fortunately, Ric Edelman, one of the most influential experts in the financial field, shows investors how they can engage and thrive in today's new investment marketplace. Featuring the prophetic insights you'd expect from one of

Connecting theory with real-life applications, this is the first ever textbook to equip students with a comprehensive knowledge of all the key concepts in bionanotechnology. By bridging the interdisciplinary gap from which bionanotechnology emerged, it provides a systematic introduction to the subject, accessible to students from a wide variety of backgrounds. Topics range from nanomaterial preparation, properties and biofunctionalisation, and analytical methods used in bionanotechnology, to bioinspired and DNA nanotechnology, and applications in biosensing, medicine and tissue engineering. Throughout the book, features such as 'Back to basics' and 'Research report' boxes enable students to build a strong theoretical knowledge and to link this to practical applications and up-to-date research. With over 200 detailed, full-colour illustrations and more than 100 end-of-chapter problems, this is an essential guide to bionanotechnology for any student studying this exciting, fast-developin

Learn about the latest advances in high-brightness X-ray physics and technology with this authoritative text. Drawing upon the most recent theoretical developments, pre-eminent leaders in the field guide readers through the fundamental principles and techniques of high-brightness X-ray generation from both synchrotron and free-electron laser sources. A wide range of topics is covered, including high-brightness synchrotron radiation from undulators, self-amplified spontaneous emission, seeded high-gain amplifiers with harmonic generation, ultra-short pulses, tapering for higher power, free-electron laser oscillators, and X-ray oscillator and amplifier configuration. Novel mathematical approaches and numerous figures accompanied by intuitive explanations enable easy understanding of key concepts, whilst practical considerations of performance-improving techniques and discussion of recent experimental results provide the tools and knowledge needed to address current research problems in t

The ultimate goal of competition law is to promote competition and, in most jurisdictions, to enhance consumer welfare. Competition policy may be set aside due to special and exceptional circumstances, such as a financial crisis that threatens the stability of an economy. It is therefore important to have a clear understanding of competition law and the exceptions to it. The key issue that this book addresses is whether a financial crisis can justify the adoption of a more lenient approach to established legal standards as a result of the risks of the systemic crisis to the entire market. It provides an analysis of exceptions to competition law and policy, particularly in the context of a financial crisis, explores the rationale of competition law in the light of conflicting interests, and serves as a valuable practical guide for policy makers as well as practitioners in the field.

The article-based thesis is becoming increasingly common, especially in the 'hard' sciences such as biology, medicine and technology, and is beginning to replace the traditional monograph. Format guidelines vary among universities. This is the first book to summarise the main features, showing the PhD student how to prepare a thesis in such a format. The suggestions are highly practical; both its good and bad examples from published theses support the author's wise advice on all aspects of such theses. Poor figures are not only scrutinised in detail but also redrawn for comparison. Guidance also covers the issues of reprint permissions and copyright. This informative and accessible book, from the author of How to Write and Illustrate a Scientific Paper, has been developed through the author's extensive teaching experience in scientific writing and also his experience as a journal editor. It is therefore an indispensable guide to article-based thesis success.

An essential guide to this major contemporary issue, Consanguinity in Context is a uniquely comprehensive account of intra-familial marriage. Detailed information on past and present religious, social and legal practices and prohibitions is presented as a backdrop to the preferences and beliefs of the 1100+ million people in consanguineous unions. Chapters on population genetics, and the role of consanguinity in reproductive behaviour and genetic variation, set the scene for critical analyses of the influence of consanguinity on health in the early years of life. The discussion on consanguinity and disorders of adulthood is the first review of its kind and is particularly relevant given the ageing of the global population. Incest is treated as a separate issue, with historical and present-day examples examined. The final three chapters deal in detail with practical issues, including genetic testing, education and counselling, national and international legislation and imperatives, and

This definitive guide provides advanced students and researchers with a detailed yet accessible overview of all of the central topics of meteor science. Leading figures from the field summarise their active research on themes ranging from the physical composition of meteoroids to the most recent optical and radar observations and ongoing theoretical developments. Crucial practical issues are also considered, such as the risk posed by meteoroids - to spacecraft, and on the ground - and future avenues of research are explored. Taking advantage of the latest dynamical models, insights are offered into meteor flight phenomena and the evolution of meteoroid streams and complexes, as well as describing the in-depth laboratory analysis of recovered material. The rapid rate of progress in twenty-first-century research makes this volume essential reading for anyone who wishes to understand how recent developments broaden our understanding of meteors, meteoroids and their origins.

J. P. Droop (1882–1963) was a classical field archaeologist. After graduating from Trinity College, Cambridge, in 1904 he worked as a field archaeologist for the British School at Athens, and was appointed Chair of Classical Archaeology at Liverpool University in 1914. This volume was intended as a guide to practical archaeological excavation and was first published in 1915 as part of the Cambridge Archaeological and Ethnological series. At the time of publication, archaeology was starting to become a more scientific and academic discipline, as can be seen in Droop's arguments on the importance of archaeological context and knowledge of stratification on site. The development of excavation as a scientifically based practice is shown by the emphasis on planning of the site, in contrast to earlier guides to excavation. This volume provides insights into the development of the theory as well as the practice of archaeology.

STOP LETTING EVERYTHING AFFECT YOU is a transformative guide for anyone who overthinks every interaction, gets stuck in emotional chaos, and finds themselves trapped in cycles of self-sabotage. With raw honesty and practical wisdom, Daniel Chidiac reveals why small things ruin your entire day and offers proven strategies to finally break free.This book will teach you how to: Stop letting little things ruin your entire day.Stop self-sabotaging.Set healthy boundaries without feeling guilty.Recognize the difference between real guilt and manipulation.Break the cycle of overthinking before it spirals out of control.Stop taking everything so personally and free yourself from emotional reactivity.Identify toxic patterns in relationships and walk away without regret.Be more in control and feel better everyday.Shift your mindset from victimhood to self-empowerment.Learn the art of emotional detachment-how to be unbothered without becoming cold.Move forward unapologetically, without feeling the

A comprehensive guide to restoring images degraded by motion blur, bridging the traditional approaches and emerging computational photography-based techniques, and bringing together a wide range of methods emerging from basic theory as well as cutting-edge research. It encompasses both algorithms and architectures, providing detailed coverage of practical techniques by leading researchers. From an algorithms perspective, blind and non-blind approaches are discussed, including the use of single or multiple images; projective motion blur model; image priors and parametric models; high dynamic range imaging in the irradiance domain; and image recognition in blur. Performance limits for motion deblurring cameras are also presented. From a systems perspective, hybrid frameworks combining low-resolution-high-speed and high-resolution-low-speed cameras are described, along with the use of inertial sensors and coded exposure cameras. Also covered is an architecture exploiting compressive sensi

John Dewey's Democracy and Education is the touchstone for a great deal of modern educational theory. It covers a wide range of themes and issues relating to education, including teaching, learning, educational environments, subject matter, values, and the nature of work and play. This Handbook is designed to help experts and non-experts to navigate Dewey's text. The authors are specialists in the fields of philosophy and education; their chapters offer readers expert insight into areas of Dewey work that they know well and have returned to time and time again throughout their careers. The Handbook is divided into two parts. Part I features short companion chapters corresponding to each of Dewey's chapters in Democracy and Education. These serve to guide readers through the complex arguments developed in the book. Part II features general articles placing the book into historical, philosophical and practical contexts and highlighting its relevance today.

John Dewey's Democracy and Education is the touchstone for a great deal of modern educational theory. It covers a wide range of themes and issues relating to education, including teaching, learning, educational environments, subject matter, values, and the nature of work and play. This Handbook is designed to help experts and non-experts to navigate Dewey's text. The authors are specialists in the fields of philosophy and education; their chapters offer readers expert insight into areas of Dewey work that they know well and have returned to time and time again throughout their careers. The Handbook is divided into two parts. Part I features short companion chapters corresponding to each of Dewey's chapters in Democracy and Education. These serve to guide readers through the complex arguments developed in the book. Part II features general articles placing the book into historical, philosophical and practical contexts and highlighting its relevance today.

Written as a response to the increasing utilization of minimally invasive procedures in children, this state-of-the-art book provides a comprehensive review of pediatric cytopathology with histopathologic correlation, focusing particularly on those entities unique to the pediatric population and highlighting differences between children and adult patients. As most pathologic diagnoses require knowledge of clinical presentation and/or imaging features, these are integral parts of the work-up in each chapter. This comprehensive guide provides optimal use of the newest diagnostic techniques (including molecular, genetic and immunohistochemical studies) to help overcome diagnostic challenges. The book is illustrated with more than 1000 high-quality color images and a password in each copy of the book provides the reader with full electronic access to all text and images. This book will provide a practical resource for practicing pediatric pathologists and cytopathologists, and a valuable e

In the 25 years since the 'Bodmer Report' kick-started the public understanding of science movement, there has been something of a revolution in science communication. However, despite the ever-growing demands of the public, policy-makers and the media, many scientists still find it difficult to successfully explain and publicise their activities or to understand and respond to people's hopes and concerns about their work. Bringing together experienced and successful science communicators from across the academic, commercial and media worlds, this practical guide fills this gap to provide a one-stop resource covering science communication in its many different forms. The chapters provide vital background knowledge and inspiring ideas for how to deal with different situations and interest groups. Entertaining personal accounts of projects ranging from podcasts, to science festivals, to student-run societies give working examples of how scientists can engage with their audiences and demo

In the 25 years since the 'Bodmer Report' kick-started the public understanding of science movement, there has been something of a revolution in science communication. However, despite the ever-growing demands of the public, policy-makers and the media, many scientists still find it difficult to successfully explain and publicise their activities or to understand and respond to people's hopes and concerns about their work. Bringing together experienced and successful science communicators from across the academic, commercial and media worlds, this practical guide fills this gap to provide a one-stop resource covering science communication in its many different forms. The chapters provide vital background knowledge and inspiring ideas for how to deal with different situations and interest groups. Entertaining personal accounts of projects ranging from podcasts, to science festivals, to student-run societies give working examples of how scientists can engage with their audiences and demo

A Reference Grammar of Spanish is a comprehensive handbook on the structure of the Spanish language. Keeping technical terminology to a minimum, it provides a detailed yet clear point of reference on all the intricacies of Spanish grammar, covering word order, parts of speech, verb use, syntax, gender, number, alphabet, and pronunciation. Accompanied by a wealth of carefully chosen examples, it looks at Spanish in Iberia, the USA, Mexico, and Argentina, and demonstrates the differences between these varieties. It is designed specifically with English-speaking learners in mind, and contains useful tools such as a glossary of terms, an index, and a detailed examination of different registers of the language. Clearly structured and systematically organised, this volume is set to become the standard guide to the grammar of contemporary Spanish, and will be an invaluable resource for teachers and students, as well as a practical supplement to textbooks and classroom study.

A Reference Grammar of Spanish is a comprehensive handbook on the structure of the Spanish language. Keeping technical terminology to a minimum, it provides a detailed yet clear point of reference on all the intricacies of Spanish grammar, covering word order, parts of speech, verb use, syntax, gender, number, alphabet, and pronunciation. Accompanied by a wealth of carefully chosen examples, it looks at Spanish in Iberia, the USA, Mexico, and Argentina, and demonstrates the differences between these varieties. It is designed specifically with English-speaking learners in mind, and contains useful tools such as a glossary of terms, an index, and a detailed examination of different registers of the language. Clearly structured and systematically organised, this volume is set to become the standard guide to the grammar of contemporary Spanish, and will be an invaluable resource for teachers and students, as well as a practical supplement to textbooks and classroom study.

What is the one thing that no one can do without? Water. Where water crosses boundaries – be they economic, legal, political or cultural – the stage is set for disputes between different users trying to safeguard access to a vital resource, while protecting the natural environment. Without strategies to anticipate, address, and mediate between competing users, intractable water conflicts are likely to become more frequent, more intense, and more disruptive around the world. In this book, Delli Priscoli and Wolf investigate the dynamics of water conflict and conflict resolution, from the local to the international. They explore the inexorable links between three facets of conflict management and transformation: Alternative Dispute Resolution (ADR), public participation, and institutional capacity. This practical guide will be invaluable to water management professionals, as well as to researchers and students in engineering, economics, geography, geology, and political science who are i

A History of Women's Writing in Italy offers a comprehensive historical account of writing by women in Italy. Covering writing from the Middle Ages to the present day, it moves away from narrow definitions of literature, and brings to the reader's attention other forms of expression such as letter writing, religious and devotional writing, scholarly and philosophical essays, travel writing, and journalism. Contributors point to the considerable practical, social and ideological difficulties faced by women in writing and presenting their work to a wider reading public, but also highlight the resourcefulness and determination of women through the centuries in making their voices heard. Extensive guides to further reading and a detailed guide to more than two hundred writers form an integral part of the volume. The international team of contributors have produced a striking work of scholarship and research, which will be invaluable for students and scholars alike.

This guide to bioremediation in cold regions is designed to aid environmental practitioners, industry, and regulators in the remediation of petroleum spills and contaminated sites in cold regions. Remediation design and technology used in temperate climates does not necessarily work in cold climates, and cleanup takes longer due to shorter treatment seasons, sub-freezing temperatures, ground freezing and thawing, and limited bioactivity. Environmental engineers and scientists from eight countries working in the polar regions combine their experiences and expertise with petroleum contamination to write this book. It contains in-depth discussions on regulations, freezing and frozen ground, identification and adaptations of cold-tolerant bacteria, contaminant transport in cold soils and permafrost, temperature effects on biodegradation, analytical methods, treatability studies, and nutritional requirements for bioremediation. Emphasis is given to practical and effective bioremediation met

This guide to bioremediation in cold regions is designed to aid environmental practitioners, industry, and regulators in the remediation of petroleum spills and contaminated sites in cold regions. Remediation design and technology used in temperate climates does not necessarily work in cold climates, and cleanup takes longer due to shorter treatment seasons, sub-freezing temperatures, ground freezing and thawing, and limited bioactivity. Environmental engineers and scientists from eight countries working in the polar regions combine their experiences and expertise with petroleum contamination to write this book. It contains in-depth discussions on regulations, freezing and frozen ground, identification and adaptations of cold-tolerant bacteria, contaminant transport in cold soils and permafrost, temperature effects on biodegradation, analytical methods, treatability studies, and nutritional requirements for bioremediation. Emphasis is given to practical and effective bioremediation met

The third edition of the Color Atlas of Emergency Trauma brings the reader to the bedside of patients with traumatic injuries, at one of the largest and busiest trauma centers in North America. It includes over 1200 images, designed as a comprehensive visual and reference guide to emergency trauma care. Organized by major body regions, this atlas explores the full spectrum of common and uncommon traumatic injuries, including those caused by firearms, stab wounds, blunt trauma, crush injury, and burns. It also covers special patient groups, such as pregnant, pediatric and geriatric populations. Each chapter is augmented with patient images at presentation, radiographic, intraoperative and autopsy images, and color illustrations and photographs showing key anatomy from the cadaver laboratory. With common pitfalls discussed and invaluable tips from a multidisciplinary group of experienced trauma care providers, this book is a useful and practical resource for all those involved in trauma

Management of the airway is an important and challenging aspect of many clinicians' work and is a source of complications and litigation. The new edition of this popular book remains a clear, practical and highly-illustrated guide to all necessary aspects of airway management. The book has been updated throughout, to cover all changes to best practice and clinical management and provides extensive coverage of the key skills and knowledge required to manage airways in a wide variety of patients and clinical settings. The best of the previous editions has been preserved, whilst new chapters on videolaryngoscopy, awake tracheal intubation, lung separation, airway ultrasonography, airway management in an epidemic and many more have been added. This is an essential text for anyone who manages the airway including trainees and specialists in anaesthesia, emergency medicine, intensive care medicine, prehospital medicine as well as nurses and other healthcare professionals.

Although depression is a major cause of illness and disability, the quality of care offered is often poor. Research evidence demonstrating how the quality of primary care can be improved is dispersed in different academic journals and written in technical jargon. Depression in Primary Care: Evidence and Practice summarizes this research in a clear and useable format. This collection of high quality reviews of research evidence takes the form of a series of clinical and economic evaluations. Each provides a clear summary of the best evidence from trials and an accessible 'how to do it' guide, written by international experts. Global approaches towards the organization and delivery of primary care for depression are presented, from the UK, North America, Europe and the developing world. An important source of practical guidance about how to implement quality improvement programs in clinical practice, this book will assist practitioners, researchers and policy makers alike.

What are the models used in phylogenetic analysis and what exactly is involved in Bayesian evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you choose and apply these models, which parameterisations and priors make sense, and how can you diagnose Bayesian MCMC when things go wrong? These are just a few of the questions answered in this comprehensive overview of Bayesian approaches to phylogenetics. This practical guide: • Addresses the theoretical aspects of the field • Advises on how to prepare and perform phylogenetic analysis • Helps with interpreting analyses and visualisation of phylogenies • Describes the software architecture • Helps developing BEAST 2.2 extensions to allow these models to be extended further. With an accompanying website providing example files and tutorials (http://beast2.org/), this one-stop reference to applying the latest phylogenetic models in BEAST 2 will provide essential guidance for all users – from those using phylogeneti

The cytologic method of pathology is now one of the most widely used diagnostic modalities worldwide. This new and practical text in cytopathology is an organ-based guide for professionals in which malignant and benign tumors are the predominant focus, but the full spectrum of infectious and inflammatory disorders will also be presented in detail, and in both adult and pediatric populations. Coverage is not limited to findings from only the light microscope but also includes many examples of other genetic, molecular, and immunologic diagnostic modalities, giving pathologists diagnostic and clinical criteria needed when formulating a diagnosis and differential diagnosis. This book is illustrated with more than 2000 full color photomicrographs and accompanied by a CD-ROM of all images in a downloadable format. Differential Diagnosis in Cytopathology proves to be the most comprehensive text in a market in which no other has focused exclusively on essential diagnostic criteria.

With a design-centric approach, this textbook bridges the gap between fundamental analog electronic circuit textbooks and more advanced RF IC design texts. The major issues that must be taken into account when combining analog and digital circuit building blocks are covered, together with the key criteria and parameters that are used to describe system-level performance. Simple circuit models enable a robust understanding of high-frequency design fundamentals, and SPICE simulations are used to check results and fine-tune the design. With solved design examples to guide the reader through the decision process that accompanies each design task, this is an ideal textbook for senior undergraduate and graduate courses in RF CMOS circuits, RF circuit design, and high-frequency analog circuit design. Analog integrated circuit designers and RF circuit designers in industry who need help making design choices will also find this a practical and valuable reference.

As expenditure on health care has increasingly become an area of public debate and concern, public and private health care decision-makers have called for more rigorous use of cost-benefit and cost-effectiveness analysis to guide spending. Concerns have arisen, however, about the overall quality of such analyses. This book discusses and evaluates best-practice methods of conducting cost-benefit and cost-effectiveness studies of pharmaceuticals and other medical technologies. It encompasses a wide variety of topics, ranging from measuring cost and effectiveness to discounting to the use of dynamic modelling of cost-effectiveness. The book also includes conceptual and practical aspects of cost-effectiveness analysis by researchers who have conducted applied research in these areas. Rarely does the book provide a singular solution to a measurement problem; rather, the reader is directed to choices among alternative approaches and an analysis of the advantages and disadvantages of each.

In today’s rapidly evolving digital landscape, safeguarding critical data and systems has never been more vital—or more challenging. Systematic Security: A CISO’s Playbook by Timur Qader offers a groundbreaking guide to building a resilient and scalable security practice from the ground up. Blending real-world experience with practical insights, this book lays out a phased approach to security implementation.Timur begins with describing the current state of security and the landscape security professionals find themselves in that offer both opportunity and risk. He goes on to systematically address strategic design, operational efficiency, risk-based modeling, and a rapidly growing regulatory landscape. This essential resource provides step-by-step strategies for implementing a comprehensive security framework. Whether you''re launching a new security program or transforming an existing one, this book delivers actionable insights on governance, compliance, and advanced security operati

With this comprehensive guide you will learn how to apply Bayesian machine learning techniques systematically to solve various problems in speech and language processing. A range of statistical models is detailed, from hidden Markov models to Gaussian mixture models, n-gram models and latent topic models, along with applications including automatic speech recognition, speaker verification, and information retrieval. Approximate Bayesian inferences based on MAP, Evidence, Asymptotic, VB, and MCMC approximations are provided as well as full derivations of calculations, useful notations, formulas, and rules. The authors address the difficulties of straightforward applications and provide detailed examples and case studies to demonstrate how you can successfully use practical Bayesian inference methods to improve the performance of information systems. This is an invaluable resource for students, researchers, and industry practitioners working in machine learning, signal processing, and sp