Electronic devices can now be used to analyse and modulate the electrical activity within the nervous system. This book explores how development of these devices is leading to new diagnostics and trea
Correct folding of proteins is critical for cell function, and accumulation of misfolded proteins is a feature of a number of neurodegenerative conditions. This book examines the mechanisms that ensur
Next-generation sequencing technology allows rapid sequencing of a patient's DNA. This book introduces the technology and describes how it may be used in personalized medicine to diagnose diseases su
Viruses that are transmitted via the fecal-oral route and may cause liver damage are known as enteric hepatitis viruses. These viruses, which include the hepatitis A and E viruses (HAV and HEV, respec
Prostate cancer is the second most common type of cancer and affects millions of individuals worldwide. This volume reviews our understanding of the disease, its progression, and new therapeutic appro
Neighboring cells are linked to each other by multimolecular complexes such as adherens junctions, desmosomes, and gap junctions. These complexes help maintain tissue integrity, act as barriers to per
The adaptive immune system ensures that our bodies remember pathogens so that we can rapidly mount an immune response if they are encountered again, without succumbing to infection. This volume examin
Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes
Prions are best known as the agents of mad cow and related diseases, and a growing number of proteins with prion-like properties have been implicated in diseases such as Parkinson's. But some recently
Cytokines are small proteins released by cells that regulate the behavior of other cells. They include interferons, interleukins, and tumor necrosis factor and are important regulators of the immune
Cell culture systems for specific neural cell types are essential for studies of their development and function.This laboratory manual provides step-by-step protocols for isolating specific cell popul
Cell culture systems for specific neural cell types are essential for studies of their development and function.This laboratory manual provides step-by-step protocols for isolating specific cell popul
Bone plays far more than just a structural role in our bodies. It actively communicates with our brains, kidneys, and other organs, releasing and responding to signaling molecules that regulate biolog
Ras proteins are critical molecular switches in signaling mechanisms that control cell behavior and are frequently mutated in cancer. This volume examines the functions of Ras, how its activation lead
Driverless cars are the future. That is what the tech giants, the auto industry and even the government want us to think. Almost daily there are media stories about how we will soon all be able to rip
Trade is being weaponized - and this is not good. As politicians on both sides of the Atlantic raise the stakes, trade is increasingly a tool of coercion to achieve strategic influence. This book look
Money is changing, and this book looks at where the technology of money might be taking us in the future. Technology has moved our concept of money from physical things, to unseen bits of information.
Why did Britain's cities, once the engines of the industrial revolution, decline so severely? What needs to be done if our cities are once again to be the drivers of our economy? This book answers the
Synthetic biology heralds the possibility of creating cellular machinery and genetic circuits that do not exist naturally and even entirely new organisms. This book examines what the technology can te
Cancer occurs because cells develop mutations that confer a growth advantage. Different subpopulations within the tumor can possess different mutations, and new mutations occur as the cancer progresse
The relationship between Israel and the church is one of the most debated issues in the history of theology. Some hold the view that there is almost seamless continuity between Israel and the church,
