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商品簡介
Taken from the high-impact journal Electrophoresis, these research articles on microfluidics and its application in a range of biological fields are of high interest and now available to a new readership. Alongside several review articles, this volume represents a current overview of the latest research.
作者簡介
Dr. N. Lion is a member of the Girault-Lab at the Ecole Polytechnique Federale de Lausanne, Institut des Sciences et Ingenerie Chimiques, Department for Physical and Analytical Electrochemistry.
Niels Lion studied industrial biotechnologies and instrumentation at the Ecole Centrale de Lille and at the Universite Paris XII, followed by a PhD at the Laboratory of Analytical and Physical Electrochemistry of the Ecole Polytechnique Federale de Lausanne (EPFL, Switzerland). His work consists in the hyphenation of microfluidic devices with electrospray mass spectrometry, and in a broader sense in miniaturised analytical sciences for proteomics. Dr Lion is the author of 20 papers and is regularly invited as reviewer for international journals. He is also a member of the Swiss Proteomics Society committee.
Dr. Joel S. Rossier is a founder and the chief scientific officer of the DiagnoSwiss SA company, founded in 1999. DiagnoSwiss SA is a biotechological company developing biosensor platforms based on proprietary microfluidic technologies for bioanalyses in submicroliter volume. Specialised in electrochemistry, microchip-based biosensors and protein analysis, DiagnoSwiss has published more than 35 peer-reviewed scientific articles in the recent years.
JoelS. Rossier studied physical chemistry at the Swiss Federal Institute of Technology in Zurich (ETHZ), followed by a Ph.D. thesis at the Laboratory of Analytical and Physical Electrochemistry (LEPA) of the EPFL. His work partly done in collaboration with Kansas University was focused on the development of chips for diagnostics and electrophoresis applications and was rewarded by the BioRad's Young Scientist Electrophoresis Research Award in 1998. Joel S. Rossier is Chief Scientific Officer and co-founder of DiagnoSwiss SA, a microfluidic technology provider company serving world leader companies in in-vitro-diagnostics and life science business. He is author of more than 40 peer review research articles and reviews, 15 patent applications and several book chapters. He is regularly invited as reviewer for international journals and is member of the editorial board of ELECTROPHORESIS and NANOMEDICINE. In order to keep a strong link with academic institutions, he co-founded the Swiss Proteomics Society and he has been appointed in 2005 as external lecturer at the EPFL for bioanalytical teaching.
Dr. H. Girault is Professor for physical chemistry since 1992. At the Ecole Polytechnique Federale de Lausanne, Institut des Sciences et Ingenerie Chimiques, he is leading the Department for Physical and Analytical Electrochemistry. His lab is specialized on the application of microfabrication techniques on electroanalysis and electrosyntheses as well as on the physical chemistry of liquid/liquid interphases and the charge transfer at these interphases.
Hubert H. Girault studied electrochemistry at the Ecole Nationale Superieure d'Electrochimie et d'Electrometallurgie de Grenoble (France), followed by a PhD in physical chemistry at the University of Southampton. Pr Girault was then appointed as lecturer in physical chemistry at the University of Edinburgh, where he co-founded "Ecosse Sensors", a company specialized in the fabrication of electrochemical sensors for heavy metal analysis. In 1992, Hubert Girault became Professor of Physical Chemistry at the Ecole Polytechnique Federale de Lausanne. He is the author of two textbooks, more than 230 scientific publications, and more than 10 patents. During his academic career he has supervised more than 25 PhD students. Hubert Girault is currently the director of the Institute for Chemical Sciences and Engineering at the EPFL. He has also served in the editorial board of several international publications, such as ELECTROPHORESIS, as well as in several scientific societies, such as the International Society of Electrochemistry, the Swiss Electrophoresis Society, and the French Society for Bioelectrochemistry. Hubert Girault is also a co-founder of DiagnoSwiss SA.
Niels Lion studied industrial biotechnologies and instrumentation at the Ecole Centrale de Lille and at the Universite Paris XII, followed by a PhD at the Laboratory of Analytical and Physical Electrochemistry of the Ecole Polytechnique Federale de Lausanne (EPFL, Switzerland). His work consists in the hyphenation of microfluidic devices with electrospray mass spectrometry, and in a broader sense in miniaturised analytical sciences for proteomics. Dr Lion is the author of 20 papers and is regularly invited as reviewer for international journals. He is also a member of the Swiss Proteomics Society committee.
Dr. Joel S. Rossier is a founder and the chief scientific officer of the DiagnoSwiss SA company, founded in 1999. DiagnoSwiss SA is a biotechological company developing biosensor platforms based on proprietary microfluidic technologies for bioanalyses in submicroliter volume. Specialised in electrochemistry, microchip-based biosensors and protein analysis, DiagnoSwiss has published more than 35 peer-reviewed scientific articles in the recent years.
JoelS. Rossier studied physical chemistry at the Swiss Federal Institute of Technology in Zurich (ETHZ), followed by a Ph.D. thesis at the Laboratory of Analytical and Physical Electrochemistry (LEPA) of the EPFL. His work partly done in collaboration with Kansas University was focused on the development of chips for diagnostics and electrophoresis applications and was rewarded by the BioRad's Young Scientist Electrophoresis Research Award in 1998. Joel S. Rossier is Chief Scientific Officer and co-founder of DiagnoSwiss SA, a microfluidic technology provider company serving world leader companies in in-vitro-diagnostics and life science business. He is author of more than 40 peer review research articles and reviews, 15 patent applications and several book chapters. He is regularly invited as reviewer for international journals and is member of the editorial board of ELECTROPHORESIS and NANOMEDICINE. In order to keep a strong link with academic institutions, he co-founded the Swiss Proteomics Society and he has been appointed in 2005 as external lecturer at the EPFL for bioanalytical teaching.
Dr. H. Girault is Professor for physical chemistry since 1992. At the Ecole Polytechnique Federale de Lausanne, Institut des Sciences et Ingenerie Chimiques, he is leading the Department for Physical and Analytical Electrochemistry. His lab is specialized on the application of microfabrication techniques on electroanalysis and electrosyntheses as well as on the physical chemistry of liquid/liquid interphases and the charge transfer at these interphases.
Hubert H. Girault studied electrochemistry at the Ecole Nationale Superieure d'Electrochimie et d'Electrometallurgie de Grenoble (France), followed by a PhD in physical chemistry at the University of Southampton. Pr Girault was then appointed as lecturer in physical chemistry at the University of Edinburgh, where he co-founded "Ecosse Sensors", a company specialized in the fabrication of electrochemical sensors for heavy metal analysis. In 1992, Hubert Girault became Professor of Physical Chemistry at the Ecole Polytechnique Federale de Lausanne. He is the author of two textbooks, more than 230 scientific publications, and more than 10 patents. During his academic career he has supervised more than 25 PhD students. Hubert Girault is currently the director of the Institute for Chemical Sciences and Engineering at the EPFL. He has also served in the editorial board of several international publications, such as ELECTROPHORESIS, as well as in several scientific societies, such as the International Society of Electrochemistry, the Swiss Electrophoresis Society, and the French Society for Bioelectrochemistry. Hubert Girault is also a co-founder of DiagnoSwiss SA.
目次
Chapter 1.On-line chemiluminescence detection for isoelectric focusing of heme proteins on microchips.
Chapter 2. A simple microfluidic system for efficient capillary electrophoretic separation and sensitive fluorimetric detection of DNA fragments using light-emitting diode and liquid-core waveguide techniques.
Chapter 3. Determination ob biochemical species on electrophoresis chips with an external contactless conductivity detector.
Chapter 4. In-channel indirect amperometric detection of nonelectroactive anions for electrophoresis on a poly(dimethylsiloxane) microchip.
Chapter 5. Coupling on-chip solid-phase extraction to electrospray mass spectrometry through an integrated electrospray tip.
Chapter 6. Electrospray interfacing of polymer microfluidics to MALDI-MS.
Chapter 7. Nanoliquid chromatography-mass spectrometry of oligosaccharides employing graphitized carbon chromatography on microchip with a high-accuracy mass analyzer.
Chapter 8. Chip electrospray mass spectrometry for carbohydrate analysis.
Chapter 9. Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis.
Chapter 10. Analysis of amino acids and proteins using a poly (methyl methacrylate) microfluidic system.
Chapter 11. Single cell manipulation, analytics, and label-free protein detection microfluidic devices for systems nanobiology.
Chapter 12. Fast immobilization of probe beads by dielectrophoresis-controlled adhesion in a versatile microfluidic platform for affinity assay.
Chapter 13. Droplet fusion by alternating current (AC) field electrocoalescence in microchannels.
Chapter 14. Microfluidic flow focusing: Drop size and scaling in pressure versus flow-rate-driven pumping.
Chapter 15. Aligning fast alternating current electroosmotic flow fields and characteristic frequencies with dielectrophoretic traps to achieve rapid bacteria detection.
Chapter 16. Dielectrophoresis induced clustering regimes of viable yeast cells.
Chapter 17. 3-D electrode designs for flow-through dielectrophoretic systems.
Chapter 18. Parallel mixing of photolithographically defined nanoliter volumes using elastomeric microvalve arrays.
Chapter 19. Method development and measurements of endogenous serine/threonine akt phosphorylation using capillary electrophoresis for systems biology.
Chapter 20. Comparison of a pump-around, a diffusion-driven, and a shear-driven system for the hybridization of mouse lung and testis total RNA on microarrays.
Chapter 21. Microfluidic devices for the analysis of apoptosis.
Chapter 22. Effect of iron restriction on outer membrane protein composition of pseudomonas strains studied by conventional and microchip electrophoresis.
Index.
Chapter 2. A simple microfluidic system for efficient capillary electrophoretic separation and sensitive fluorimetric detection of DNA fragments using light-emitting diode and liquid-core waveguide techniques.
Chapter 3. Determination ob biochemical species on electrophoresis chips with an external contactless conductivity detector.
Chapter 4. In-channel indirect amperometric detection of nonelectroactive anions for electrophoresis on a poly(dimethylsiloxane) microchip.
Chapter 5. Coupling on-chip solid-phase extraction to electrospray mass spectrometry through an integrated electrospray tip.
Chapter 6. Electrospray interfacing of polymer microfluidics to MALDI-MS.
Chapter 7. Nanoliquid chromatography-mass spectrometry of oligosaccharides employing graphitized carbon chromatography on microchip with a high-accuracy mass analyzer.
Chapter 8. Chip electrospray mass spectrometry for carbohydrate analysis.
Chapter 9. Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis.
Chapter 10. Analysis of amino acids and proteins using a poly (methyl methacrylate) microfluidic system.
Chapter 11. Single cell manipulation, analytics, and label-free protein detection microfluidic devices for systems nanobiology.
Chapter 12. Fast immobilization of probe beads by dielectrophoresis-controlled adhesion in a versatile microfluidic platform for affinity assay.
Chapter 13. Droplet fusion by alternating current (AC) field electrocoalescence in microchannels.
Chapter 14. Microfluidic flow focusing: Drop size and scaling in pressure versus flow-rate-driven pumping.
Chapter 15. Aligning fast alternating current electroosmotic flow fields and characteristic frequencies with dielectrophoretic traps to achieve rapid bacteria detection.
Chapter 16. Dielectrophoresis induced clustering regimes of viable yeast cells.
Chapter 17. 3-D electrode designs for flow-through dielectrophoretic systems.
Chapter 18. Parallel mixing of photolithographically defined nanoliter volumes using elastomeric microvalve arrays.
Chapter 19. Method development and measurements of endogenous serine/threonine akt phosphorylation using capillary electrophoresis for systems biology.
Chapter 20. Comparison of a pump-around, a diffusion-driven, and a shear-driven system for the hybridization of mouse lung and testis total RNA on microarrays.
Chapter 21. Microfluidic devices for the analysis of apoptosis.
Chapter 22. Effect of iron restriction on outer membrane protein composition of pseudomonas strains studied by conventional and microchip electrophoresis.
Index.
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