This volume is dedicated to a description of the instruments, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the ideas, intrumentation, and methods underlying all cryo-EM approaches which allow practictioners to easily move between them. Within each section, the articles are ordered according to the most common symmetry of the sample to which their methods are applied.
* Includes?time-tested core?methods and new innovations?applicable to any researcher * Methods included are useful to both established?researchers and newcomers to the field * Relevant background and reference information given for procedures can be used as a guide
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