VITAMINS AND CANCER PREVENTION CONTEMPORARY ISSUES IN CLINICAL NUTRITION

With increasing evidence supporting an important role for vitamins in preventing and treating cancer, their use and therapeutic benefit have emerged as factors influencing the outcome of this deadly disease.
Investigating vitamins A, E, C, D, as well as other vitamins and vitamin-like molecules, Vitamins and Cancer Prevention reviews evidence involving the correlation between vitamins and cancer prevention and examines how vitamins can be used as deterrents to neoplastic transformation in cells, experimental animals, and humans. This timely volume includes clinical trials of vitamins as therapeutic and preventive agents, studies of the roles of selected vitamins in mediating cellular transformation events, and preliminary investigations of the potential effects of vitamin deficiency and therapy in cancer patients.

Presenting an extensive range of subject matter, this scholarly book covers:
* The possible effects of carotenoids in skin cancer prevention
* Vitamin A and Beta-carotene: long-term protective effects in oral leukoplakia
* Modulation of carcinogenesis by vitamin A and its analogs
* Localized folate deficiency and cancer
* Folate, vitamin B12, and methylation interactions in tumor formation
* Vitamins E and C in neoplastic development
* 1,25-Dihydroxyvitamin D3 and hematopoietic cells
* Coenzyme Q10 deficiency in cancer patients--potential for immunotherapy with coenzyme Q10


In addition, the book explores some of the more general trends in nutrition research that may have a future impact on reducing the risk of cancer.
As research in cancer biology turns to the modification of environmental and lifestyle factors that increase the risk of cancer, Vitamins and Cancer Prevention offers timely information to researchers and clinicians involved in the study of vitamins and their role in cancer management, including oncologists, nutrition scientists, biochemists, cell and molecular biologists, and dieticians.

Contributors.

Preface (S. Laidlaw, et al.).An Approach to Studying the Possible Effects of Carotenoids in Skin Cancer Prevention (E. Greenberg).

Vitamin A and Beta-Carotene: Longterm Protective Effects in Oral Leukoplakia (H. Stich, et al.).

Modulation of Carcinogenesis by Vitamin A and Its Analogs (Retinoids) (A. Verma).

Localized Folate Deficiency and Cancer (C. Krumdieck).

Folate, Vitamin B12 and Methylation Interactions in Tumor Formation (L. Poirier).

Vitamins E and C in Neoplastic Development (M. Carpenter).

1,25-Dihydroxyvitamin D3 and Hematopoietic Cells: Applications to Cancer Therapy (M. Kizaki & H. Koeffler).

Coenzyme Q10 Deficiency in Cancer Patients: Potential for Immunotherapy with Coenzyme Q10 (K. Folkers, et al.).

The Future of Nutrition Research in Cancer Prevention (P. Greenwald).

Index.