CONFORMATIONAL ANALYSIS OF CYCLOHEXENES, CYCLOHEXADIENES & RELATED HYDROAROMATIC COMPOUNDS

This collection of articles by leading researchers is the first to focus on the conformational analysis of six-membered rings containing one or more sites of unsaturation, primarily by NMR and force field calculations. Such compounds provide a wealth of information regarding stereochemistry and dynamic conformational behavior.
Among the examples cited in the book are metabolites from polynuclear aromatic compounds, dihydroaromatics that play a critical role in the liquefaction of coal, and heteroatoms containing dihydroaromatics, which are important in many medications. The book also contains a considerable amount of NMR data and an appendix explaining the ins and outs of empirical force field calculations to the uninitiated.

Preface

Chapter 1. Conformational Analysis of Cydohexenes

Frank A. L. Anet

Chapter 2. Conformational Analysis of Six-Membered Carbocyclic Rings with Exocyclic Double Bonds

Joseph B. Lambert

Chapter 3. Conformational Analysis of 1,3-Cyclohexadienes and Related Hydroaromatics

Peter W. Rabideau and Andrzej Sygula

Chapter 4. Conformational Analysis of 1,4-Cydohexadienes and Related Hydroaromatics

Peter W. Rabideau

Chapter 5. Use of Carbon-13 Nudear Magnetic Resonance in the Conformational Analysis of Hydroaromatic Compounds

Frederick G. Morin and David M. Grant

Chapter 6. Conformational Analysis of Partially Unsaturated Six-Membered Rings Containing Heteroatoms

Slayton A. Evans, Jr.

Chapter 7. Application of Empirical Force-Field Calculations to the Conformational Analysis of Cyclohexenes, Cyclohexadienes, and Hydroaromatics

Kenny B. Lipkowitz

Chapter 8. Conformational Analysis of Hydroaromatic Metabolites of Carcinogenic Hydrocarbons and the Relation of Conformation to Biological Activity

Ronald G. Harvey

Appendix. Empirical Force-Field Method

Kenny B. Lipkowitz

Index