MICROARRAY ANALYSIS

This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverageincludes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies.

MARK SCHENA, Ph.D., the "Father of Microarray Technology," trained with Dan Koshland at U.C. Berkeley, Keith Yamamoto at UCSF, and Ron Davis at Stanford University. He published the first paper on microarrays in Science in 1995, and has given more than 80 lectures in 15 countries since 1995. Dr. Schena was featured as one of the Stars of Genomics on the 2001 NOVA television documentary on the Human Genome Project, and is currently a visiting scholar at TeleChem/arrayit.com in Sunnyvale, California.

Preface.

Introduction to Microarray Analysis.

Introduction to Chemistry.

Basics of Biochemistry.

Genes and Genomes.

Microarray Surfaces.

Targets and Probes.

Microarray Manufacturing.

Microarray Detection.

Microarray Informatics.

Methodological Architecture.

Cleanroom Technology.

Gene Expression Profiling.

Genetic Screening and Diagnostics.

Novel Microarray Technologies.

Commercial Opportunities A to Z.

Future Trends: Chips in the Clinics.

Appendix A: Prefixes.

Appendix B: Unit Abbreviations.

Appendix C: Technical Abbreviations.

Appendix D: Conversions.

Appendix E: Nucleic Acid Molecular Weight Calculations.

Appendix F: Microarray Spot Area Calculations.

Appendix G: Microarray Fluor Density Calculations.

Appendix H: Microarray Target Density Calculations.

Appendix I: Microarray Web Sites.

References.

Glossary.

Answers.

Index.