GI EPIDEMIOLOGY

This book covers both key methodological issues and the most important information in the field, disease by disease. It focuses on population-based information and studies looking at principles and approaches to diagnosis and treatment of diseases.

GI Epidemiology brings together world authorities in multiple disciplines for the very first time, to create one clear and comprehensive source. The bulk of the chapters are divided into two parts, covering methodological issues and the epidemiology of specific GI diseases. Each chapter begins with a list of key points, followed by a review written in a clear and simple style.

The methodologic chapters cover evidence-based medicine, meta-analysis, systematic reviews, genetic and molecular epidemiology, clinical trials, questionnaire design, and health economics. The disease-specific chapters note the current gaps in knowledge and suggest areas for further study.

GI Epidemiology serves as both a useful refresher and a reliable reference on the methods and techniques used in epidemiological studies for consultants and researchers in gastroenterology.

It is also an invaluable tool for fellows/trainees in gastroenterology, candidates for recertification in the combined disciplines of gastroenterology, pediatric gastroenterology and colorectal surgery, and anyone completing MPH training.

G. Richard Locke III, MD
GI Epidemiology Unit
Mayo Clinic College of Medicine
Rochester, Minnesota, USA

Yuri A. Saito, MD, MPH
GI Epidemiology Unit
Mayo Clinic College of Medicine
Rochester, Minnesota, USA

Foreword.

Preface.

Part 1: Gastrointestinal Diseases and Disorders: The Public Health.

Perspective.

1 The Importance of GI Epidemiology: G. Richard Locke III (Mayo Clinic College of Medicine) and Nicholas J. Talley (Mayo Clinic College of Medicine).

2 The Burden of Gastrointestinal and Liver Diseases: Nicholas J. Shaheen.

Part 2: Methodological Issues in GI Epidemiology.

3 Overview of Epidemiologic Methodology: L. Joseph Melton III and Steven J. Jacobsen.

4 Patient-Reported Outcomes: Ingela Wiklund.

5 GI Questionnaires: G. Richard Locke III (Mayo Clinic College of Medicine).

6 Clinical Trials: William J. Sandborn.

7 Decision Analysis: John M. Inadomi.

8 Health Economics: Dawn Provenzale and Joseph Lipscomb.

9 Systematic Reviews: Philip Schoenfeld.

10 Meta-analyses: Paul Moayyedi.

11 Large Databases for Epidemiologic Studies: Jessica A. Davila and Hashem B. El-Serag.

12 Nutritional Epidemiology: Linda E. Kelemen.

13 Infection Epidemiology and Acute Gastrointestinal Infections: Sarah J. O’Brien and Smita L.S. Halder.

14 Genetic Epidemiology: Yuri A. Saito (Miles and Shirley Fiterman Center for Digestive Diseases) and Gloria M. Petersen.

15 A Career in GI Epidemiology: Linda Rabeneck.

16 Funding Opportunities at the National Institutes of Health: James E. Everhart and Judith M. Podskalny.

Part 3: Epidemiology of Specific GI Diseases.

17 GERD, Barrett’s Esophagus and Esophageal Cancer: Yvonne Romero and G. Richard Locke III (Mayo Clinic College of Medicine).

18 Helicobacter pylori Infection, Peptic Ulcer Disease and Gastric Cancer: Olof Nyrén.

19 Dyspepsia: Nimish B. Vakil and Nicholas J. Talley (Mayo Clinic College of Medicine).

20 Upper Gastrointestinal Bleeding: James Lau and Joseph Sung.

21 Celiac Disease: Alberto Rubio-Tapia and Joseph A. Murray.

22 Measuring Utilization of Colonoscopy in Clinical Practice: David Lieberman.

23 Colorectal Carcinoma: Steven B. Ingle and Paul Limburg.

24 Irritable Bowel Syndrome: Yuri A. Saito (Miles and Shirley Fiterman Center for Digestive Diseases) and Nicholas J. Talley (Mayo Clinic College of Medicine) and G. Richard Locke III (Mayo Clinic College of Medicine).

25 Constipation: John F. Johanson.

26 Infectious Diarrhea: Crenguta Stepan and Christina M. Surawicz.

27 Inflammatory Bowel Disease: Edward V. Loftus Jr.

28 Fecal Incontinence: Adil E. Bharucha.

29 Gallstones: Torben Jørgensen.

30 Pancreatitis: Santhi Swaroop Vege and Dhiraj Yadav and Suresh T. Chari.

31 Pancreatic Cancer: Suresh T. Chari.

32 Alcoholic Liver Disease: Mary C. Dufour.

33 Cirrhosis and Hepatocellular Carcinoma: William Sanchez and Jayant A. Talwalkar.

34 Nonalcoholic Fatty Liver Disease: Paul Angulo.

35 Hepatitis B and C: W. Ray Kim.

Index