HANDBOOK OF ION CHROMATOGRAPHY 3A 2V SET

The third edition of this highly successful and established handbook has been completely revised and considerably extended, making it unrivaled in the timeliness and comprehensiveness of the information presented. This new edition runs to two volumes, with added chapters or sections covering:
- New and important applications of ion chromatography in the life sciences, such as the analysis of proteins, nucleic acids, amino acids or carbohydrates.
- New instrumentation that meets the demand for miniaturization and reduced analysis times.
- Coupling of ion chromatography to mass-spectrometric or inductively coupled plasma detectors
- Validation of ion-chromatographic methods, which is important for quality assurance
The author has played a major role in the development of ion chromatography and alongside his industrial post -- has been appointed as visiting professor at the University of Innsbruck, one of the prominent centers of chromatography research in the world.

Joachim Weiss is working for the leading instrument manufacturer Dionex and is the scientific organizer of the 17th International Ion Chromatography Symposium 2004 in Trier, Germany.

Foreword.

Preface.

Volume 1.

1 Introduction.

1.1 Historical Perspective.

1.2 Types of Ion Chromatography.

1.3 The Ion Chromatographic System.

1.4 Advantages of Ion Chromatography.

1.5 Selection of Separation and Detection Systems.

2 Theory of Chromatography.

2.1 Chromatographic Terms.

2.2 Parameters for Assessing the Quality of a Separation.

2.3 Column Efficiency.

2.4 The Concept of Theoretical Plates (Van-Deemter Theory).

2.5 Van-Deemter Curves in Ion Chromatography.

3 Anion Exchange Chromatography (HPIC).

3.1 General Remarks.

3.2 The Ion-Exchange Process.

3.3 Thermodynamic Aspects.

3.4 Stationary Phases.

3.5 Eluants for Anion Exchange Chromatography.

3.6 Suppressor Systems in Anion Exchange Chromatography.

3.7 Anion Exchange Chromatography of Inorganic Anions.

3.8 Anion Exchange Chromatography of Organic Anions.

3.9 Gradient Elution Techniques in Anion Exchange Chromatography of Inorganic and Organic Anions.

3.10 Carbohydrates.

3.11 Amino Acids.

3.12 Proteins.

3.13 Nucleic Acids.

4 Cation Exchange Chromatography (HPIC).

4.1 Stationary Phases.

4.2 Eluants in Cation Exchange Chromatography.

4.3 Suppressor Systems in Cation Exchange Chromatography.

4.4 Cation Exchange Chromatography of Alkali Metals, Alkaline-Earth Metals, and Amines.

4.5 Transition Metal Analysis.

4.6 Analysis of Polyamines.

4.7 Gradient Techniques in Cation Exchange Chromatography of Inorganic and Organic Cations.

5 Ion-Exclusion chromatography (HPICE).

5.1 The Ion-Exclusion Process.

5.2 Stationary Phases.

5.3 Eluants in Ion-Exclusion Chromatography.

5.4 Suppressor Systems in Ion-Exclusion Chromatography.

5.5 Analysis of Inorganic Acids.

5.6 Analysis of Organic Acids.

5.7 HPICE/HPIC-Coupling.

5.8 Analysis of Alcohols and Aldehydes.

5.9 Amino Acid Analysis.

5.9.1 Separation of Amino Acids.

6 Ion-Pair Chromatography (MPIC).

6.1 Survey of Existing Retention Models.

6.2 Suppressor Systems in Ion-Pair Chromatography.

6.3 Experimental Parameters that Affect Retention.

6.4 Analysis of Surface-Inactive Ions.

6.5 Analysis of Surface-Active Ions.

6.6 Applications of the Ion-Suppression Technique.

6.7 Applications of Multi-Dimensional Ion Chromatography on Multimode Phases.

7 Detection Methods in Ion Chromatography.

7.1 Electrochemical Detection Methods.

7.2 Spectrometric Detection Methods.

7.3 Other Detection Methods.

7.4 Hyphenated Techniques.

Index.

Volume 2.

8 Quantitative Analysis.

8.1 General.

8.2 Analytical Chemical Information Parameters.

8.3 Determination of Peak Areas.

8.4 Statistical Quantities.

8.5 Calibration of an Analytical Method (Basic Calibration).

8.6 Detection Criteria, Limit of Detection, Limit of Determination.

8.7 The System of Quality Control Cards.

9 Applications.

9.1 Ion Chromatography in Environmental Analysis.

9.2 Ion Chromatography in Power Plant Chemistry.

9.3 Ion Chromatography in the Semiconductor Industry.

9.4 Ion Chromatography in the Electroplating Industry.

9.5 Ion Chromatography in the Detergent and Household Product Industry.

9.6 Ion Chromatography in the Food and Beverage Industry.

9.7 Ion Chromatography in the Pharmaceutical Industry.

9.8 Ion Chromatography in Clinical Chemistry.

9.9 Oligosaccharide Analysis of Membrane Coupled Glycoproteins.

9.10 Other Applications.

9.11 Sample Preparation and Matrix Problems.

Index.