TRANSITION METALS FOR ORGANIC SYNTHESIS - BUILDING BLOCKS AND FINE CHEMICALS 2E 2V SET

Already in its second edition, here over 70 internationally renowned authors cover the vast range of possible applications for transition metals in industry as well as academia. This two-volume work presents the current state of research and applications in this economically and scientifically important area of organic synthesis as well as for the production of fine chemicals.
Over 1,000 illustrations and the balanced presentation allow readers fast access to the thorough compilation of applications, making this an indispensable work for everyone working with such metals whether professionally or engaged in academic research.

Matthias Beller, born in 1962, studied chemistry at the University of G?ttingen, Germany, where he completed his doctoral thesis in 1989 in the group of Prof. L.-F. Tietze. As recipient of a Liebig scholarship from the Association of the German Chemical Industry, he then spent a postdoctoral fellowship in the group of Prof. K. Barry Sharpless at the Massachusetts Institute of Technology in Cambridge, USA. From 1991 to 1995, Beller joined the Hoechst AG, where he most recently directed the "Homogeneous Catalysis" project. At the beginning of 1996 he moved to the Technical University of Munich as Professor for Inorganic Chemistry. 1998, he relocated to the University of Rostock to head the Leibniz Institute for Organic Catalysis (IfOK) and to occupy a chair in catalysis. Matthias Beller is a member of the board of Dechema's Catalysis Section, the German Catalysis Competence Network ("ConNeCat") as well as the Innovationsagentur Mecklenburg-Vorpommern. He is also a member of the Association for Technical Sciences of the Union of German Academies of Sciences and Humanities.

Carsten Bolm was born in Braunschweig in 1960. He studied chemistry at the TU Braunschweig (Germany) and at the University of Wisconsin, Madison (USA). In 1987 he obtained his doctorate with Professor Reetz in Marburg (Germany). After postdoctoral training with Professor Sharpless at MIT, Cambridge (USA), Carsten Bolm worked in Basel (Switzerland) with Professor Giese to obtain his habilitation. In 1993 he became Professor of Organic Chemistry at the University of Marburg (Germany), and since 1996 he has a chair of Organic Chemistry at the RWTH Aachen (Germany). His awards include the Heinz-Maier-Leibnitz prize, the ADUC-Jahrespreis for habilitands, the annual prize for Chemistry of the Akademie der Wissenschaften zu G?ttingen, the Otto-Klung prize, and the Otto-Bayer award. He held visiting professorships at the Universities in Madison (US), Paris (France), Florence (Italy), Milano (Italy) , and Namur (Belgium), and he was fellow of the Japan Society for the Promotion of Science (JSPS).

Preface.

1 General.

1.1 Basic Aspects of Organic Synthesis with Transition Metals (Barry M. Trost).

1.2 Concepts for the Use of Transition Metals in Industrial Fine Chemical Synthesis (Wilhelm Keim).

2 Transition Metal-Catalyzed Reactions.

2.1 Hydroformylation: Applications in the Synthesis of Pharmaceuticals and Fine Chemicals (Matthias Beller and Kamal Kumar).

2.2 New Synthetic Applications of Tandem Reactions under Hydroformylation Conditions (Peter Eilbracht and Axel M. Schmidt).

2.3 Multiple Carbon-Carbon Bond Formations under Hydroformylation Conditions (Peter Eilbracht and Axel M. Schmidt).

2.4 Hydrocarboxylation and Hydroesterification Reactions Catalyzed by Transition Metal Complexes (Bassam El Ali and Howard Alper).

2.5 The Amidocarbonylation of Aldehydes (Axel Jacobi von Wangelin, Helfried Neumann, Dirk Gördes, and Matthias Beller).

2.6 Transition Metal-catalyzed Alkene and Alkyne Hydrocyanations (Albert L. Casalnuovo and T.V. Rajan Babu).

2.7 Cyclopropanation (Andreas Pfaltz).

2.8 Cyclomerization of Alkynes (H. Bönnemann and W. Brijoux).

2.9 Isomerization of Olefin and the Related Reactions (Sei Otsuka and Kazuhide Tani).

2.10 Coupling of Aryl and Alkyl Halides with Organoboron Reagents (Suzuki Reaction) (Alexander Zapf).

2.11 Transition Metal-Catalyzed Arylation of Amines and Alcohols (Alexander Zapf, Matthias Beller, and Thomas H. Riermeier).

2.12 Catalytic Enantioselective Alkylation of Alkenes by Chiral Metallocenes (Amir H. Hoveyda).

2.13 Palladium-Catalyzed Olefinations of Aryl Halides (Heck Reaction) and Related Transformations (Matthias Beller, Alexander Zapf, and Thomas H. Riermeier).

2.14 Palladium-Catalyzed Allylic Substitutions (Andreas Heumann).

2.15 Alkene and Alkyne Metathesis in Organic Synthesis (Oliver R. Thiel).

2.16 Homometallic Lanthanoids in Synthesis: Lanthanide Triflate-catalyzed Synthetic Reactions (Sh&umarc; Kobayashi).

2.17 Lanthanide Complexes in Asymmetric Two-Center Catalysis (Masakatsu Shibasaki, Hiroaki Sasai, and Naoki Yoshikawa).

2.18 Bismuth Reagents and Catalysts in Organic Synthesis (Axel Jacobi von Wangelin).

3 Transition Metal-Mediated Reactions.

3.1 Fischer-Type Carbene Complexes (Karl Heinz Dötz and Ana Minatti).

3.2 Titanium–Carbene Mediated Reactions (Nicos A. Petasis).

3.3 The McMurry Reaction and Related Transformations (Alois Fürstner).

3.4 Chromium(II)-Mediated and -Catalyzed C-C Coupling Reactions (David M. Hodgson and Paul J. Comina).

3.5 Manganese(III)-Based Oxidative Free-Radical Cyclizations (Barry B. Snider).

3.6 Titanium-Mediated Reactions (Rudolf O. Duthaler, Frank Bienewald, and Andreas Hafner).

3.7 Zinc-Mediated Reactions (Axel Jacobi von Wangelin and Mathias U. Frederiksen).

3.8 The Conjugate Addition Reaction (A. Alexakis).

3.9 Carbometalation Reactions of Zinc Enolate Derivatives (Daniella Banon-Tenne and Ilan Marek).

3.10 Iron Acyl Complexes (Karola Rück-Braun).

3.11 Iron–Diene Complexes (Hans-Joachim Knölker).

3.12 Chromium-Arene Complexes (Hans-Günther Schmalz and Florian Dehmel).

3.13 Pauson-Khand Reactions (D. Strübing and M. Beller).

Subject Index.