商品簡介
The Cytochrome P450 enzymes play a role in the toxicology of xenobiotics. This work reviews the current status of the field since 1996, explains the structure and function of these enzymes, and examines their many forms and substrates. Some areas discussed include the evolution of the P450 superfamily, the P450 catalytic cycle, and substrate selectivity and metabolism. The book is of interest to graduate students and postgraduates, and for professionals in the pharmaceutical industry, including those involved in regulation and chemical risk assessment. Lewis is a reader in molecular toxicology at the School of Biological Sciences, University of Surrey, UK. Annotation c. Book News, Inc., Portland, OR (booknews.com)
