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For nephrologists, neurologists, neurosurgeons, and cardiologists, Toyoda (cerebrovascular medicine, National Cerebral and Cardiovascular Center, Japan) brings together specialists in nephrology, neurology, cardiology, and other disciplines from Europe, Asia, and the US for 13 articles that examine the relationship between the brain, stroke, and kidney, particularly stroke and chronic kidney disease. They examine cerebrorenal interaction and stroke; underlying concepts, including the inhibition of the renin-angiotensin-aldosterone system and obesity and heart failure as a mediator of the cerebrorenal interaction; the risk of clinical and subclinical brain damage in chronic kidney disease patients, with discussion of carotid atherosclerosis in kidney disease, kidney disease and cognitive function, and the risk of stroke; primary prevention of stroke in kidney disease, including the role of 24-hour blood pressure management and preventing stroke and systemic embolism; and acute/chronic management for stroke patients with chronic kidney and end-stage disease, including stroke features and management in dialysis patients, thrombolysis and hyperacute reperfusion therapy, and antiplatelet therapy. Annotation c2013 Book News, Inc., Portland, OR (booknews.com)
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