商品簡介
As we reach a better understanding of the need for early intervention and prevention to slow or halt Metabolic Syndrome, we also need to understand the basic science to develop better treatment. With the goal of stimulating new research and better therapeutics, contributors from epidemiology, physiology, molecular biology, molecular biochemistry and clinical practice offer cross-disciplinary analyses on this complex disease. Topics here include the role of the rise of obesity in insulin resistance, treatment options (weight loss, exercise, hormones and surgery), links with cardiovascular disease from an epidemiological perspective, influence of the sympatho-adrenal system, insulin action and endothelial function, vascular disease in pre-diabetic animal models, highly sensitive C-reactive protein, insulin signaling, insulin resistance and dyslipidemia, pancreatic islet therapy in obesity; influence from glucagon peptides, insulin receptor substrates, tyrosine kinase, muscle fat, alterations in atypical protein kinase C activation, the liver and glucose homeostasis; and the chronomics of the syndrome. Annotation c2008 Book News, Inc., Portland, OR (booknews.com)