商品簡介
Arey, a pharmaceutical researcher, brings together other scientists and researchers from industry and universities in the US and Belgium, who examine biased receptor signaling in physiology, pharmacology, and therapeutics. In eight chapters, they discuss its history and basic pharmacological principles, the role of the cell background in biased signaling, the application of signaling bias to new therapeutic drug therapy for seven transmembrane (G protein-coupled) receptors, biased signaling and conformational dynamics in nuclear hormone receptors, biasing receptor tyrosine kinase signaling pathways, conformational mechanisms of signaling bias of ion channels, protein conformational dynamics and signaling in evolution and pathophysiology, and the possibilities of biased signaling in the development of improved therapeutics. Annotation c2014 Ringgold, Inc., Portland, OR (protoview.com)
