商品簡介
Sixty-three international researchers contribute to a two-volume set providing a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways, with particular attention given to apoptosis in human diseases such as different forms of cancer and neurodegenerative diseases. Coverage in Volume I includes the pathophysiological processes including the mechanisms by which normal cells are transformed to malignant cells, regulation of cell growth, differentiation and apoptosis by oncogenes and tumor suppressor genes, consequences of DNA damage and the ability of cells to repair damaged DNA in response to stress stimuli, molecular events in metastasis and angiogenesis, and the roles of transcription factors and cytokines in cell survival and apoptosis. For graduate students, postdoctoral and medical fellows, and scientists with a working knowledge of biology and pathology. Annotation c2007 Book News, Inc., Portland, OR (booknews.com)
