Modeling of Nanotoxicity ― Molecular Interactions of Nanomaterials With Bionanomachines

This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology. This book also provides a critical assessment of advanced molecular modeling and other computational techniques to nanosafety, and highlights current and future biomedical applications of nanoparticles in relation to nanosafety.

Ruhong Zhou is currently a Distinguished Research Staff Scientist and Head of the Soft Matter Science Group at the IBM Thomas J. Watson Research Center; he is also an Adjunct Professor at the Chemistry Department of Columbia University. He serves as Editor-in-Chief of Current Physical Chemistry, Editor of (Nature) Scientific Reports, Guest Editor ofNanoscale, and is Editorial Board Member of six other international journals. He sits on the Board of Directors of the Telluride Science and Research Center (TSRC), and the Scientific Advisory Board of Center for Multiscale Theory and Simulation, University of Chicago. He was elected to AAAS Fellow and APS Fellow in 2011.