Orexin and Sleep ─ Molecular, Functional and Clinical Aspects

This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.

Takeshi Sakurai, MD, PhD., is one of the discoverers of neuropeptide orexin, which plays a highly important role in sleep/wakefulness state regulation. He is a well-recognized sleep researcher both nationally and internationally, and has authored many publications in the field of sleep and orexin. S.R. Pandi-Perumal, M.Sc., has authored many publications in the field of sleep and biological rhythms. He has published a number of books on various aspects of sleep medicine with Springer: Neuroendocrine Correlates of Sleep/wakefulness (Springer USA, 2005); Sleep and Sleep Disorders: a Neuropsychopharmacological approach (Landes Bioscience/Eurekha.com and Springer SBM, USA, 2006); Clinical Pharmacology of Sleep (Birkhauser-Verlag, Switzerland, 2006); Neuroimmunology of Sleep (Springer-Verlag, USA, 2007); Primary Care Sleep Medicine (Humana Press/Springer-Verlag, USA, 2007); Serotonin: physiology, functions, and regulation (Birkhauser-Verlag, Switzerland, 2008); Sleep and Quality of life in medical illness (Humana/Springer, USA, 2008); Narcolepsy: a clinical guide (Springer, 2010) GABA and Sleep: Molecular, Functional and Clinical Aspects (Springer Basel, Switzerland, 2010) Jaime M Monti is Professor, Department of Pharmacology and Therapeutics, School of Medicine, Clinics Hospital, University of the Republic, Uruguay. He is a member of the International College of Neuropsychopharmacology, Sleep Research Society (USA), European Sleep Research Society, and the Argentinian Society of Sleep Medicine.