Negative Affective States and Cognitive Impairments in Nicotine Dependence

Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals.

In addition, the book also examines animal models that researchers can utilize to examine these dysfunctions’ biological bases, making it an invaluable resource for investigators seeking to develop targeted treatments for nicotine dependence that ameliorate symptoms of dependence, as well as those associated with premorbid differences in affective or cognitive function.

• Provides a unique view of nicotine dependence that emphasizes a users’ negative reinforcement rather than positive reinforcement
• Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use
• Includes both clinical and preclinical perspectives
• Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments