DNA Methyltransferases ― Role and Function
商品資訊
系列名:Advances in Experimental Medicine and Biology
ISBN13:9783319436227
出版社:Springer Verlag
作者:Albert Jeltsch (EDT); Renata Z. Jurkowska (EDT)
出版日:2016/11/22
裝訂:精裝
規格:23.5cm*15.5cm (高/寬)
定價
:NT$ 12600 元優惠價
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90 折 11340 元
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作者簡介
商品簡介
DNA Methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans can lead to cancer and other severe diseases. The book describes the enzymes and their mechanisms in bacteria, humans and plants and also explains the biological role of DNA methylation, functioning as an essential epigenetic mark. In addition, the book discusses the role of DNA methylation in diseases, including the contribution of mutations in DNA methyltransferases to cancer; it explains targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as the biological role and enzymatic processes of DNA demethylation. Furthermore, the book summarizes recent methods for the analysis of DNA methylation in human DNA. The book represents a comprehensive state-of-the-art- work and is a must-have for advanced researchers in the field of DNA methylation and epigenetics.
作者簡介
Albert Jeltsch is Pofessor for Biochemistry at the University of Stuttgart, Germany.
Renata Jurkowska is Group Leader in Biochemistry and Molecular Epigenetics at the University of Stuttgart, Germany.
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