The Human Frontal Lobes ─ Functions and Disorders

This authoritative work, now thoroughly revised, has given thousands of clinicians, students, and researchers a state-of-the-art understanding of the human frontal lobes--the large brain region that plays a critical role in behavior, cognition, health, and disease. Leading authorities from multiple disciplines address the anatomy and chemistry of the frontal cortex, neuropsychological assessments of capabilities unique to the frontal lobes, the nature of (and possible treatment avenues for) frontotemporal dementia and related conditions, and implications for understanding and treating neuropsychiatric disorders, such as schizophrenia, mania, and depression. Illustrations include eight pages in full color.

New to This Edition:
*Reflects a decade of important research advances in such areas as functional connectivity mapping of frontal and frontal-subcortical circuits.
*Incorporates significant new information on frontotemporal dementia and other neurological disorders.
*Expanded section on neuropsychiatric disorders, with new chapters on apathy, dissociative states, and antisocial behavior.
*Chapters on salience networks, normal brain aging, white matter diseases, and clinical trials.
*Increased attention to brain processes involved in moral reasoning, empathy, decision making, and other key human capabilities.

Bruce L. Miller, MD, is the A. W. and Mary Margaret Clausen Distinguished Professor of Neurology at the University of California, San Francisco (UCSF), and Director of the UCSF Memory and Aging Center. Dr. Miller is a behavioral neurologist focused on dementia, with special interests in brain-behavior relationships as well as the genetic and molecular underpinnings of disease. He currently conducts research on frontotemporal dementia, oversees a program on healthy aging, and helps lead two privately funded research consortia. He also works with the National Football League to help with educating and assessing players in regard to brain health. Dr. Miller is a recipient of the Potamkin Award from the American Academy of Neurology, the Raymond D. Adams Lectureship from the American Neurological Association, the J. Elliot Royer Award from the San Francisco Neurological Society, the UCSF Annual Faculty Research Lectureship in Clinical Science, and the Gene D. Cohen Research Award in Creativity and Aging from the National Center for Creative Aging, among many other honors. With more than 600 scientific publications, Dr. Miller has served since 1984 as Scientific Director of the John Douglas French Alzheimer’s Foundation.
 
Jeffrey L. Cummings, MD, ScD, is Director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada, and Cleveland, Ohio. He is the Camille and Larry Ruvo Chair for Brain Health at the Cleveland Clinic Neurological Institute and Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. A leading authority on Alzheimer's disease, Dr. Cummings is interested in clinical trials, developing new therapies for brain diseases, and the interface of neuroscience and society. He is a recipient of the Henderson Award from the American Geriatrics Society, the Research Award from the John Douglas French Alzheimer’s Foundation, the Ronald and Nancy Reagan Research Award from the Alzheimer’s Association, and the Distinguished Scientist Award from the American Association of Geriatric Psychiatry, among many other honors. Dr. Cummings has more than 700 scientific publications and is a past president of the Behavioral Neurology Society and the American Neuropsychiatric Association.