Small Animal Imaging ─ Basics and Practical Guide

This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.

Since 2008 Professor Dr. Fabian Kiessling is leading the Institute for Experimental Molecular Imaging at the Helmholtz Center of Applied Engineering of the RWTH-University in Aachen. Aim of his research is the development of novel diagnostic probes and imaging tools for a disease specific diagnosis and therapy monitoring. In this context, the main focus is on the investigation of angiogenesis related processes. Fabian Kiessling studied Medicine and graduated at the University of Heidelberg. Until the end of 2002, he worked as resident in the Department of Radiology at the German Cancer Research Center (DKFZ) in Heidelberg. In 2003 he changed to the Department of Medical Physics in Radiology of the DKFZ as leader of the Molecular Imaging group. In parallel he did his clinical training at different Departments of the University of Heidelberg and received the board certification as clinical Radiologist in 2007. Fabian Kiessling habilitated in experimental radiology in 2006. He is author of more than 240 publications and book chapters, received several research awards, among those the ?Emil Salzer Price for Cancer Research” and the “Richtzenhain Price”. Shortly after his change to the RWTH-Aachen University he founded the invivoContrast GmbH together with Professor Matthias Brautigam, which is distributing diagnostic probes for the preclinical market.