Polycystic Kidney Disease
商品資訊
系列名：Methods in Signal Transduction Series
ISBN13：9781138603899
出版社：PBKTYFRL
作者：Jinghua Hu; Yong (St. John's University Yu Queens NY)
出版日：2019/11/14
裝訂／頁數：精裝／346頁
規格：24cm*16.2cm*2.6cm (高/寬/厚)
商品簡介
This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies.
Key Features
- Explores the role of cilia in polycystic kidney disease
- Focuses on myriad state-of-the-art methods and techniques
- Reviews specific mutations integral to this autosomal genetic disease
- Includes discussions of model systems
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