1. Bioinformatics strategies for molecular diagnostics
o Candidate gene selection and analysis of Rare diseases
o Candidate gene selection and analysis of Complex diseases
2. Bioinformatics tools for Molecular Diagnostics
o Single Gene Disorders - Case studies
o Polygenic Disorders - Case studies
o Genetic Tests - Tools, Results, Interpretation
3. Bioinformatics approaches for Genetic Risk Marker Studies
o Population Genetics
o Gene Polymorphisms
o Gene Expression Assays
o Genetic Statistics
4. Bioinformatics for Disease Prognostics
o Pharmacogenetics
o Efficacy
o Toxicity
o Adverse reactions
o Biomarker Selection and Monitoring
o Precision Medicine
5. Bioinformatics tools in Gene Therapy
o Enzyme Replacement- Bioinformatics role is limited
o Gene Replacement (Knock-in)
o Gene Silencing(RNAi)
o Gene Editing (CRISPR)
6. Bioinform
atics tools in Disease Therapeutics - Data analysis tools and applicationo Drug Discovery
o Protein-Drug Interactions
o Drug-Body metabolism studies
o Microbiome
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