Preclinical MRI of the Kidney: Methods and Protocols

Preface...
Table of Contents...
Contributing Authors...

Part I Introduction

1. Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies
Andreas Pohlmann, Susan J. Back, Andrea Fekete, Iris Friedli, Stefanie Hectors, Neil Peter Jerome, Min-Chi Ku, Dario Livio Longo, Martin Meier, Jason M. Millward, Jo緌 S. Periquito, Erdmann Seeliger, Suraj D. Serai, Sonia Waiczies, Steven Sourbron, Christoffer Laustsen, and Thoralf Niendorf

Part II Animal Models, Preparation, Monitoring, and Physiological Interventions

2. Animal Models of Renal Pathophysiology and Disease
Adam Hosszu, Tamas Kaucsar, Erdmann Seeliger, and Andrea Fekete

3. Preparation and Monitoring of Small Animals in Renal MRI
Tamas Kaucsar, Adam Hosszu, Erdmann Seeliger, Henning M. Reimann, and Andrea Fekete

4. Reversible (Patho-)Physiologically Relevant Test Interventions: Rationale and Examples
Kathleen Cantow, Mechthild Ladwig-Wiegard, Bert Flemming, Andrea Fekete, Adam Hosszu, Erdmann Seeliger

5. Preparation of Ex Vivo Rodent Phantoms for Developing, Testing, and Training MR Imaging of the Kidney and Other Organs
Jason M. Millward, Jo緌 S. Periquito, Paula Ramos Delgado, Christian Prinz, Thoralf Niendorf, and Sonia Waiczies

Part III Basic Concepts of Measurement Techniques

6. Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts
Kathleen Cantow, Roger G. Evans, Dirk Grosenick, Thomas Gladytz, Thoralf Niendorf, Bert Flemming, and Erdmann Seeliger

7. Ultrasound and Photoacoustic Imaging of the Kidney: Basic Concepts and Protocols
Sandra Meyer, Dieter Fuchs, and Martin Meier

8. Hardware Considerations for Preclinical Magnetic Resonance of the Kidney
Paula Ramos Delgado, Ekkehard Ktermann, Andr?Kne, Jason M. Millward, Thoralf Niendorf, Andreas Pohlmann, and Martin Meier

9. MRI Mapping of Renal T1: Basic Concept
Stefanie Hectors, Sabrina Doblas, Philippe Garteiser, Gwena螔 Pag? Bernard E. Van Beers, John C. Waterton, and Octavia Bane

10. MRI Mapping of the Blood Oxygenation Sensitive Parameter T2* in the Kidney: Basic Concept
Lu-Ping Li, Bradley Hack, Erdmann Seeliger, and Pottumarthi V. Prasad

11. Renal Diffusion Weighted Imaging (DWI) for Apparent Diffusion Coefficient (ADC), Intra Voxel Incoherent Motion (IVIM), and Diffusion Tensor Imaging (DTI): Basic Concept
Neil Peter Jerome, Anna Caroli, and Alexandra Ljimani

12. Dynamic Contrast Enhancement (DCE)-MRI Derived Renal Perfusion and Filtration: Basic Concepts
Michael Pedersen, Pietro Irrera, Walter Dastr? Frank G. Z闤lner, Kevin M. Bennett, Scott C. Beeman, G. Larry Bretthorst, Joel R. Garbow, and Dario Livio Longo

13. Non-Invasive Renal Perfusion Measurement Using Arterial Spin Labelling (ASL) MRI: Basic Concept
Min-Chi Ku, Mar燰 A. Fern嫕dez-Seara, Frank Kober, and Thoralf Niendorf

14. Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI: Basic Concepts
Dario Livio Longo, Pietro Irrera, Lorena Consolino, Phillip Zhe Sun, and Michael T. McMahon

15. Sodium (23Na) MRI of the Kidney: Basic Concept
James T. Grist, Esben S vs Hansen, Frank G. Z闤lner, and Christoffer Laustsen

16. Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concepts
Cornelius von Morze, Galen D. Reed, Zhen J. Wang, Michael A. Ohliger, and Christoffer Laustsen

17. Functional Imaging Using Fluorine (19F) MR Methods: Basic Concepts
Sonia Waiczies, Christian Prinz, Ludger Starke, Jason M. Millward, Paula Ramos Delgado, Jens Rosenberg, Marc Nazar? Helmar Waiczies, Andreas Pohlmann, and Thoralf Niendorf

18. MR Elastography of the Abdomen: Basic Concepts
Suraj D. Serai and Meng Yin

Part IV Experimental Protocols

19. Monitoring Renal H